Ruthenium-catalyzed direct arylation of C–H bonds in aromatic amides containing a bidentate directing group: significant electronic effects on arylation

Sequential C sp 3H Arylation and Olefination: Total Synthesis of the Proposed Structure of Pipercyclobutanamide A

(2012) Will R. Gutekunst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonnatural Amino Acid Synthesis by Using Carbon-Hydrogen Bond Functionalization Methodology

(2012) Ly Dieu Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Based Catalytic System for the Direct C3-Arylation of Furan-2-carboxamides and Thiophene-2-carboxamides

(2012) Karima Si Larbi et al.   ChemCatChem

Sulfoximines: A Reusable Directing Group for Chemo- and Regioselective ortho CH Oxidation of Arenes

(2012) M. Ramu Yadav et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Ortho-Arylation of Benzamides via Direct sp2 C–H Bond Activation

(2012) Dan-Dan Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Reductive Elimination from Arylpalladium Cyanide Complexes

(2012) Jessica L. Klinkenberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions

(2012) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Tosylcarboxamide as a Transformable Directing Group for Pd-Catalyzed C–H Ortho-Arylation

(2012) Florent Péron et al.   ORGANIC LETTERS

Improved Protocol for Indoline Synthesis via Palladium-Catalyzed Intramolecular C(sp2)–H Amination

(2012) Gang He et al.   ORGANIC LETTERS

Pd-Catalyzed Arylation/Oxidation of Benzylic C–H Bond

(2012) Yongju Xie et al.   ORGANIC LETTERS

Palladium-Catalyzed Alkenylation and Alkynylation of ortho-C(sp2)–H Bonds of Benzylamine Picolinamides

(2012) Yingsheng Zhao et al.   ORGANIC LETTERS

Pd(II)-Catalyzed Primary-C(sp3)–H Acyloxylation at Room Temperature

(2012) Raja K. Rit et al.   ORGANIC LETTERS

Ruthenium-Catalyzed C–H Bond Arylations of Arenes Bearing Removable Directing Groups via Six-Membered Ruthenacycles

(2012) Lutz Ackermann et al.   ORGANIC LETTERS

Well-Defined Ruthenium(II) Carboxylate as Catalyst for Direct C–H/C–O Bond Arylations with Phenols in Water

(2012) Lutz Ackermann et al.   ORGANIC LETTERS

Catalytic C–H bond arylation of aryl imines and oxazolines in water with ruthenium(II)-acetate catalyst

(2012) Bin Li et al.   TETRAHEDRON

Direct Arylation of 6-Phenylpurine and 6-Arylpurine Nucleosides by Ruthenium-Catalyzed CH Bond Activation

(2011) Mahesh K. Lakshman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Practical Strategy for the Structural Diversification of Aliphatic Scaffolds through the Palladium-Catalyzed Picolinamide-Directed Remote Functionalization of Unactivated C(sp3)H Bonds

(2011) Gang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Formation of CC and CN Bonds through Palladium-Catalyzed Dual CH Activation: Synthesis of Phenanthridinones

(2011) Guan-Wu Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Cross-coupling Reactions of Organoboranes: An Easy Method for C–C Bonding

(2011) Akira Suzuki et al.   CHEMISTRY LETTERS

C-H Bond Functionalization of Arylpyrimidines Catalyzed by an in situ Generated Ruthenium(II) Carboxylate System and the Construction of Tris(heteroaryl)-Substituted Benzenes

(2011) Bogdan Štefane et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Angiotensin II Receptor Blockers by Means of a Catalytic System for C–H Activation

(2011) Masahiko Seki et al.   JOURNAL OF ORGANIC CHEMISTRY

Preparative Scale Synthesis of the Biaryl Core of Anacetrapib via a Ruthenium-Catalyzed Direct Arylation Reaction: Unexpected Effect of Solvent Impurity on the Arylation Reaction†

(2011) Stéphane G. Ouellet et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Regioselective Carbonylation of Unactivated C(sp3)–H Bonds by Ruthenium Carbonyl

(2011) Nao Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Direct Ethynylation of C(sp3)–H Bonds in Aliphatic Carboxylic Acid Derivatives

(2011) Yusuke Ano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterocycle Synthesis via Direct C–H/N–H Coupling

(2011) Enrico T. Nadres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium Catalyzed Intramolecular Amination of C(sp3)–H and C(sp2)–H Bonds at γ and δ Positions

(2011) Gang He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis and Structural Revision of the Piperarborenines via Sequential Cyclobutane C–H Arylation

(2011) Will R. Gutekunst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Autocatalysis for C–H Bond Activation by Ruthenium(II) Complexes in Catalytic Arylation of Functional Arenes

(2011) Emmanuel Ferrer Flegeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Chelation-Assisted Transformations Involving Ortho C–H Bond Activation: Regioselective Oxidative Cycloaddition of Aromatic Amides to Alkynes

(2011) Hirotaka Shiota et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Direct ortho-Alkynylation of Aromatic Carboxylic Acid Derivatives

(2011) Yusuke Ano et al.   ORGANIC LETTERS

Palladium-Catalyzed Alkylation ofortho-C(sp2)–H Bonds of Benzylamide Substrates with Alkyl Halides

(2011) Yingsheng Zhao et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Direct C–H Bond Arylations of Heteroarenes

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Ruthenium Complexes of κ(P)- and κ(P)-η6-Coordinated KITPHOS Monophosphines: Efficient Catalysts for the Direct Ortho Arylation of 2-Phenylpyridine andN-Phenylpyrazole with Aryl Chlorides

(2011) Simon Doherty et al.   ORGANOMETALLICS

Sequential Catalysis for the Production of Sterically Hindered Amines: Ru(II)-Catalyzed C–H Bond Activation and Hydrosilylation of Imines

(2011) Bin Li et al.   ACS Catalysis

(η6-Arene)ruthenium(N-heterocyclic carbene) Complexes for the Chelation-Assisted Arylation and Deuteration of Arylpyridines: Catalytic Studies and Mechanistic Insights

(2010) Amparo Prades et al.   ADVANCED SYNTHESIS & CATALYSIS

CH Bond Functionalization in Water Catalyzed by Carboxylato Ruthenium(II) Systems

(2010) Percia B. Arockiam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd0/PR3-Catalyzed Arylation of Nicotinic and Isonicotinic Acid Derivatives

(2010) Masayuki Wasa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Facile Benzo-Ring Construction via Palladium-Catalyzed Functionalization of Unactivated sp3C−H Bonds under Mild Reaction Conditions

(2010) Yiqing Feng et al.   ORGANIC LETTERS

Mechanistic Insight into Direct Arylations with Ruthenium(II) Carboxylate Catalysts

(2010) Lutz Ackermann et al.   ORGANIC LETTERS

A Highly Efficient Ruthenium(II) Catalyst with (1,2-Diarylvinyl)phosphine Ligands for Direct OrthoArylation of 2-Arylpyridine with Aryl Chlorides

(2010) Bingran Yu et al.   ORGANOMETALLICS

Ruthenium-Catalyzed C-H Bond Functionalizations of 1,2,3-Triazol-4-yl-Substituted Arenes: Dehydrogenative Couplings Versus Direct Arylations

(2010) Lutz Ackermann et al.   SYNTHESIS-STUTTGART

Pd-catalyzed ortho-arylation of phenylacetamides, benzamides, and anilides with simple arenes using sodium persulfate

(2010) Charles S. Yeung et al.   Chemical Science

O2insertion into a palladium(ii)-hydride bond: Observation of mechanistic crossover between HX-reductive-elimination and hydrogen-atom-abstraction pathways

(2010) Michael M. Konnick et al.   Chemical Science

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Total Synthesis of Celogentin C by Stereoselective CH Activation

(2009) Yiqing Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling

(2009) Gary A. Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

Recent advances in aryl–aryl bond formation by direct arylation

(2009) Gerard P. McGlacken et al.   CHEMICAL SOCIETY REVIEWS

RuCl3⋅x H2O-Catalyzed Direct Arylation of Arenes with Aryl Chlorides in the Presence of Triphenylphosphine

(2009) Ning Luo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium-Catalyzed Direct Arylations ofN-Aryl 1,2,3-Triazoles with Aryl Chlorides as Electrophiles

(2009) Lutz Ackermann et al.   ChemSusChem

Examination of the Mechanism of Rh2(II)-Catalyzed Carbazole Formation Using Intramolecular Competition Experiments

(2009) Benjamin J. Stokes et al.   JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Carbonylation at Ortho C−H Bonds in Aromatic Amides Leading to Phthalimides: C−H Bond Activation Utilizing a Bidentate System

(2009) Satoshi Inoue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Aryl C−H Bonds Activation/Acetoxylation Utilizing a Bidentate System

(2009) Fa-Rong Gou et al.   ORGANIC LETTERS

Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates

(2009) Fabio Bellina et al.   TETRAHEDRON

Ortho-selective Arylation of Arylazoles with Aryl Bromides Catalyzed by Ruthenium Complexes

(2008) Shuichi Oi et al.   CHEMISTRY LETTERS

Carbon−Hydrogen Bond Functionalization Approach for the Synthesis of Fluorenones andortho-Arylated Benzonitriles

(2008) Dmitry Shabashov et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Arylation of Arene C−H Bonds by Cooperative Action of NHCarbene−Ruthenium(II) Catalyst and Carbonate via Proton Abstraction Mechanism

(2008) Ismail Özdemir et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assisted Ruthenium-Catalyzed C−H Bond Activation: Carboxylic Acids as Cocatalysts for Generally Applicable Direct Arylations in Apolar Solvents

(2008) Lutz Ackermann et al.   ORGANIC LETTERS

Dehydrogenation of Inert Alkyl Groups via Remote C−H Activation: Converting a Propyl Group into a π-Allylic Complex

(2008) Ramesh Giri et al.   ORGANOMETALLICS

Nitrogen-directed ortho-arylation and -heteroarylation of aromatic rings catalyzed by ruthenium complexes

(2008) Shuichi Oi et al.   TETRAHEDRON