Journal
CHEMICAL SCIENCE
Volume 4, Issue 9, Pages 3538-3543Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3sc51222c
Keywords
-
Categories
Funding
- EPSRC
- WestCHEM
- University of Glasgow
- Pfizer
- AstraZeneca
- Engineering and Physical Sciences Research Council [1163520, 1229249, EP/I027165/1] Funding Source: researchfish
- EPSRC [EP/I027165/1] Funding Source: UKRI
Ask authors/readers for more resources
A palladium-catalyzed difunctionalization of unactivated alkenes with tethered nucleophiles is reported. The versatile reaction occurs with simple allylic halides and can be carried out under air. The methodology provides rapid access to a wide array of desirable heterocyclic targets, as illustrated by a concise synthesis of the widely prescribed antidepressant citalopram.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available