Synthetically modified Fc domains as building blocks for immunotherapy applications

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Release of Photoactivatable Drugs from Plasmonic Nanoparticles for Targeted Cancer Therapy

(2011) Yun-Ling Luo et al.   ACS Nano

Selective Formation of Covalent Protein Heterodimers with an Unnatural Amino Acid

(2011) Benjamin M. Hutchins et al.   CHEMISTRY & BIOLOGY

Introduction to current and future protein therapeutics: A protein engineering perspective

(2011) Paul J. Carter   EXPERIMENTAL CELL RESEARCH

Site-Specific Coupling and Sterically Controlled Formation of Multimeric Antibody Fab Fragments with Unnatural Amino Acids

(2011) Benjamin M. Hutchins et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid Chemoselective Bioconjugation through Oxidative Coupling of Anilines and Aminophenols

(2011) Christopher R. Behrens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

(2011) H. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual-Surface Modified Virus Capsids for Targeted Delivery of Photodynamic Agents to Cancer Cells

(2010) Nicholas Stephanopoulos et al.   ACS Nano

Discovery and Development of Therapeutic Aptamers

(2010) P.R. Bouchard et al.   Annual Review of Pharmacology and Toxicology

Identification of Highly Reactive Sequences For PLP-Mediated Bioconjugation Using a Combinatorial Peptide Library

(2010) Leah S. Witus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia

(2010) Prabodhika R. Mallikaratchy et al.   NUCLEIC ACIDS RESEARCH

Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach

(2009) Xiaohong Fang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Receptor-Fc fusion therapeutics, traps, and MIMETIBODY™ technology

(2009) Chichi Huang   CURRENT OPINION IN BIOTECHNOLOGY

Targeting a Homogeneously Glycosylated Antibody Fc To Bind Cancer Cells Using a Synthetic Receptor Ligand

(2009) Junpeng Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Viral Capsid DNA Aptamer Conjugates as Multivalent Cell-Targeting Vehicles

(2009) Gary J. Tong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag

(2009) P. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrolytic Stability of Hydrazones and Oximes

(2008) Jeet Kalia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

(2008) Dihua Shangguan et al.   JOURNAL OF PROTEOME RESEARCH

Optimization of a Biomimetic Transamination Reaction

(2008) Rebecca A. Scheck et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

(2008) Jagath R Junutula et al.   NATURE BIOTECHNOLOGY

An engineered selenocysteine defines a unique class of antibody derivatives

(2008) T. Hofer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA