4.8 Article

Gold meets enamine catalysis in the enantioselective α-allylic alkylation of aldehydes with alcohols

Journal

CHEMICAL SCIENCE
Volume 3, Issue 9, Pages 2859-2863

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2sc20478a

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Synergetic gold(I)- and organo-catalysis proved to be efficient towards the intramolecular stereoselective alpha-allylic alkylation of aldehydes with simple primary and secondary alcohols. High diastereo- and enantioselectivity were recorded.

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