Journal
CHEMICAL SCIENCE
Volume 2, Issue 12, Pages 2321-2325Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sc00409c
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- Novartis International AG
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A general and efficient condition for palladium-catalyzed Heck alkynylation in batch was developed using a novel precatalyst. In addition, the first general and efficient continuous-flow protocol for the coupling of alkynes with aryl bromides in the absence of copper was reported.
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