Journal
JACC-CARDIOVASCULAR IMAGING
Volume 3, Issue 8, Pages 854-859Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jcmg.2010.06.007
Keywords
echocardiograph; exercise test; heart failure; left ventricular assist device
Funding
- Fonds de la recherche en sante du Quebec
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Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients. (J Am Coll Cardiol Img 2010; 3:854-9) (C) 2010 by the American College of Cardiology Foundation
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