Article
Multidisciplinary Sciences
Daniel Kreft, Gabriele Doblhammer, Rudolf F. Guthoff, Stefanie Frech
Summary: The study identified age, gender, multiple morbidities, and diabetes as major risk factors for severe binocular vision impairment and blindness (SVI/B) in individuals aged 50 and older. Additionally, secondary glaucoma, retinal vascular occlusion, and angle-closure glaucoma were high-risk eye diseases associated with SVI/B. While population density did not have an impact, individuals residing in wealthier regions were found to be at a higher risk for SVI/B compared to those in less wealthy regions.
Article
Green & Sustainable Science & Technology
Chenlu Li, Xiaoxu Wu, Xiaofeng Wang, Jie Yin, Alina Zheng, Xiaofan Yang
Summary: This study investigated the long-term relationship between ecological environment and socioeconomic drivers with DF transmission in Guangzhou, China. Population density, night-time light, travel, and land use were identified as key factors affecting DF transmission. A DF model based on a generalized additive model performed the best, capturing nonlinear relationships and extreme outbreaks of DF. Suggestions for prevention policies were made based on ecological environment and socioeconomic factors.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Immunology
Jean Y. Ko, Melissa L. Danielson, Machell Town, Gordana Derado, Kurt J. Greenlund, Pam Daily Kirley, Nisha B. Alden, Kimberly Yousey-Hindes, Evan J. Anderson, Patricia A. Ryan, Sue Kim, Ruth Lynfield, Salina M. Torres, Grant R. Barney, Nancy M. Bennett, Melissa Sutton, H. Keipp Talbot, Mary Hill, Aron J. Hall, Alicia M. Fry, Shikha Garg, Lindsay Kim
Summary: The study identified factors independently associated with COVID-19-associated hospitalizations, including having three or more underlying medical conditions, severe obesity, chronic kidney disease, diabetes, obesity, hypertension, and asthma. These findings provide valuable information for targeted preventive and therapeutic interventions.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Environmental Sciences
Nerida Nadia H. Valero, Paula Prist, Maria Uriarte
Summary: Leishmaniasis, a vector-borne disease caused by Leishmania spp., is influenced by various factors such as vegetation cover, climate, and socioeconomic factors. Studies have shown that high vegetation cover, economic inequality, precipitation, and other factors are associated with the probability of leishmaniasis occurrence, highlighting the need for effective public health policies and interventions based on these risk factors.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Virology
Jessica Navero-Castillejos, Rosa Benitez, Nuria Torner, Jose Munoz, Daniel Camprubi-Ferrer, Aida Peiro-Mestres, Elena Sulleiro, Aroa Silgado, Veronica Gonzalo, Teresa Falgueras, Izaskun Alejo-Cancho, Montserrat Roldan, Virginia Plasencia, Rosa Albarracin, Josefa Perez, Alexander Navarro, Ana Calderon, Rosa Rubio, Mireia Navarro, Miguel Mico, Jaume Llaberia, Maria Navarro, Josep Barrachina, Anna Vilamala, Carmina Marti, Maria Angeles Pulido, Maria Paz Sanchez-Seco, Ana Vazquez, Ana Martinez, Mireia Jane, Miguel Julian Martinez
Summary: This study conducted molecular characterization of 104 dengue cases detected in Catalonia, northeastern Spain, from 2013 to 2018, including imported infections and the first autochthonous case in the region. All four dengue serotypes were detected in travelers, reflecting global circulation in endemic areas. The primary travel-related case of the 2018 autochthonous transmission was not identified, but molecular analysis revealed the origin of the dengue virus strain.
Article
Public, Environmental & Occupational Health
Jehangir Khan, Muhammad Adil, Gang Wang, Tsheten Tsheten, Dongjing Zhang, Wenjie Pan, Munir Ahmad Khan, Inayat Ur Rehman, Xiaoying Zheng, Zhongdao Wu, Yu Wu
Summary: The study revealed that multiple poor socioeconomic factors are influencing dengue transmission in KP province, with higher knowledge, attitude, and practice levels potentially leading to lower frequency of dengue in non-hotspot districts.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Maria K. Sobczyk, Jie Zheng, George Davey Smith, Tom R. Gaunt
Summary: We conclude that careful triangulation of MR with RCT evidence should involve consideration of similarity of phenotypes across study designs, intervention intensity and duration, study population demography and health status, comparator group, intervention goal and quality of evidence.
Article
Public, Environmental & Occupational Health
David Conway, Jan Hovanec, Wolfgang Ahrens, Alastair Ross, Ivana Holcatova, Pagona Lagiou, Diego Serraino, Cristina Canova, Lorenzo Richiardi, Claire Healy, Kristina Kjaerheim, Gary J. Macfarlane, Peter Thomson, Antonio Agudo, Ariana Znaor, Paul Brennan, Daniele Luce, Gwenn Menvielle, Isabelle Stucker, Simone Benhamou, Heribert Ramroth, Paolo Boffetta, Marta Vilensky, Leticia Fernandez, Maria Paula Curado, Ana Menezes, Alexander Daudt, Rosalina Koifman, Victor Wunsch-Filho, Amy Lee Yuan-Chin, Mia Hashibe, Thomas Behrens, Alex D. McMahon
Summary: Low occupational socioeconomic prestige, position, and manual work are associated with head and neck cancer risk, which is only partially explained by smoking, alcohol, and occupational exposures. Perceptual occupational psychosocial status (SIOPS) appears to be the strongest socioeconomic factor relative to socioeconomic position and manual/non-manual work in relation to head and neck cancer risk.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2021)
Article
Multidisciplinary Sciences
Rhaquel de Morais Alves Barbosa Oliveira, Francisca Kalline de Almeida Barreto, Geovana Praca Pinto, Isabella Timbo Queiroz, Fernanda Montenegro de Carvalho Araujo, Kilma Wanderley Lopes, Regina Lucia Sousa do Vale, Daniele Rocha Queiroz Lemos, John Washington Cavalcante, Andre Machado Siqueira, Livia Carla Vinhal Frutuoso, Elisabeth Carmen Duarte, Antonio Silva Lima Neto, Andre Ricardo Ribas Freitas, Luciano Pamplona de Goes Cavalcanti
Summary: This study evaluated factors associated with deaths from chikungunya (CHIK) in Fortaleza, Brazil. The results showed that chronic kidney disease and previous heart disease, presence of fever, abdominal pain, apathy, dyspnea, and arthritis were significantly associated with death. Laboratory findings such as leukocytosis, leukopenia, thrombocytopenia, neutropenia, and lymphopenia were also linked to higher risk of death.
Article
Clinical Neurology
Marijne Vandebergh, Nicolas Degryse, Benedicte Dubois, An Goris
Summary: Multiple sclerosis (MS) is a complex disease involving genetic variants and environmental factors, including obesity, vitamin D deficiency, Epstein-Barr virus infection, and smoking. Leveraging genetics through the Mendelian randomization paradigm helps inform prevention strategies for MS by studying the impact of environmental factors on susceptibility. This approach draws parallels with observational studies and randomized controlled trials, highlighting the challenges and opportunities for future research in this area.
JOURNAL OF NEUROLOGY
(2022)
Article
Medicine, General & Internal
David C. Lee, Stephanie L. Orstad, Rania Kanchi, Samrachana Adhikari, Pasquale E. Rummo, Andrea R. Titus, Jose O. Aleman, Brian Elbel, Lorna E. Thorpe, Mark D. Schwartz
Summary: This study aimed to evaluate the impact of demographic, social, and geographic factors on glycemic control in diabetes patients. The results showed that female patients and those with lower baseline glycemic levels were more likely to achieve within-range glycemic control during follow-up. Surprisingly, older patients and those with more comorbidities were also more likely to achieve within-range glycemic control. However, the associations between geographic factors and glycemic control varied across different community types.
Article
Virology
Larissa Domingues Castilho de Arruda, Marta Giovanetti, Vagner Fonseca, Marina Castilhos Souza Umaki Zardin, Gislene Garcia de Castro Lichs, Silvia Asato, Ana Olivia Pascoto Esposito, Miriam Tokeshi Mueller, Joilson Xavier, Hegger Fritsch, Mauricio Lima, Carla de Oliveira, Elaine Vieira Santos, Livia de Mello Almeida Maziero, Danila Fernanda Rodrigues Frias, Danielle Ahad das Neves, Liliane Ferreira da Silva, Ellen Caroline Rodrigues Barretos, Paulo Eduardo Tsuha Oshiro, Bianca Modafari Goday, Jessica Klener Lemos dos Santos, Simone Kashima, Carlos F. C. de Albuquerque, Rodrigo Fabiano do Carmo Said, Alexander Rosewell, Luiz Henrique Ferraz Demarchi, Julio Croda, Luiz Carlos Junior Alcantara, CrhistinneCavalheiro Maymone Goncalves
Summary: Since its discovery in early 1916, dengue fever has caused extensive urban outbreaks in Brazil, posing a serious threat to public health. A genomic surveillance training program was conducted in collaboration with local health authorities, resulting in the generation of 177 DENV genome sequences collected during a period of high dengue fever cases. The study identified the co-circulation of different dengue serotypes and diverse viral lineages, indicating multiple introduction events of viral strains in the region. The findings highlight the complex and changing dynamics of DENV transmission and emphasize the value of ongoing surveillance activities in informing public health actions.
Article
Public, Environmental & Occupational Health
Eric R. A. Vos, Gerco den Hartog, Rutger M. Schepp, Patricia Kaaijk, Jeffrey van Vliet, Kina Helm, Gaby Smits, Alienke Wijmenga-Monsuur, Janneke D. M. Verberk, Michiel van Boven, Rob S. van Binnendijk, Hester E. de Melker, Liesbeth Mollema, Fiona R. M. van der Klis
Summary: During the first epidemic wave, the overall seroprevalence of SARS-CoV-2 in the Netherlands was estimated to be 2.8%, with the highest rates among 18-39 year-olds and the lowest among children aged 2-17. Those taking immunosuppressants and individuals from the Orthodox-Reformed Protestant community had higher odds of being seropositive. Anosmia/ageusia was the most discriminative symptom between seropositive and seronegative individuals.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2021)
Article
Medicine, General & Internal
Chun-Han Lo, Long H. Nguyen, David A. Drew, Erica T. Warner, Amit D. Joshi, Mark S. Graham, Adjoa Anyane-Yeboa, Fatma M. Shebl, Christina M. Astley, Jane C. Figueiredo, Chuan-Guo Guo, Wenjie Ma, Raaj S. Mehta, Sohee Kwon, Mingyang Song, Richard Davies, Joan Capdevila, Carole H. Sudre, Jonathan Wolf, Yvette C. Cozier, Lynn Rosenberg, Lynne R. Wilkens, Christopher A. Haiman, Loic Le Marchand, Julie R. Palmer, Tim D. Spector, Sebastien Ourselin, Claire J. Steves, Andrew T. Chan
Summary: This study found that compared with non-Hispanic White participants, the risk for a positive COVID-19 test was increased for non-Hispanic Black and Hispanic participants in the US, and for Black, South Asian, and Middle Eastern participants in the UK. This elevated risk was associated with living in more deprived communities according to the NDI/IMD indices.
Article
Environmental Sciences
Maximiliano Giraud-Billoud, Paula Cuervo, Jorgelina C. Altamirano, Marcela Pizarro, Julieta N. Aranibar, Adolfo Catapano, Hector Cuello, Gisela Masachessi, Israel A. Vega
Summary: Wastewater-based epidemiology (WBE) is an emerging tool that provides temporal and spatial information on a population's health status. By combining WBE with epidemiological surveillance, researchers were able to track the dynamics of COVID-19 infections, showing a positive correlation between viral load in wastewater and diagnosed cases. WBE proves to be a useful epidemiological indicator for anticipating COVID-19 case increases and monitoring the pandemic's progress and different waves of infections.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Multidisciplinary Sciences
Carlos Eduardo Raymundo, Marcella Cini Oliveira, Tatiana de Araujo Eleuterio, Suzana Rosa Andre, Marcele Goncalves da Silva, Eny Regina da Silva Queiroz, Roberto de Andrade Medronho
Summary: Social inequality in Brazilian municipalities increased the risk of COVID-19, while better social development was negatively associated with disease risk. Improved access to health services enhanced disease diagnosis and notification, and was linked to higher case numbers in municipalities.
Article
Multidisciplinary Sciences
Marlos Melo Martins, Antonio Jose Ledo Alves da Cunha, Jaqueline Rodrigues Robaina, Carlos Eduardo Raymundo, Arnaldo Prata Barbosa, Roberto de Andrade Medronho
Summary: The study analyzed 21 cohort studies and found that among fetuses/neonates of pregnant women with Zika virus infection during pregnancy, central nervous system abnormalities had the highest prevalence rate.
Article
Water Resources
Carmen I. R. Froes-Asmus, Armando Meyer, Antonio Jose Ledo A. da Cunha, Nataly Damasceno, Luiz Eduardo Gomes, Ronir Raggio Luiz, Ana Cristina Simoes Rosa, Silvana do Couto Jacob, Arnaldo Prata Barbosa, Thatiana V. R. de B. Fernandes, Roberto Medronho, Volney de Magalhaes Camara
Summary: The PIPA project is the first birth cohort study in Brazil focusing on the investigation of environmental pollutant exposure effects on child health. The pilot study conducted in Rio de Janeiro found that pregnant women from poor communities in the city, and their children, are exposed to several harmful pollutants.
EXPOSURE AND HEALTH
(2021)
Correction
Infectious Diseases
Marcella Cini Oliveira, Tatiana de Araujo Eleuterio, Allan Bruno de Andrade Correa, Lucas Dalsenter Romano da Silva, Renata Coelho Rodrigues, Bruna Andrade de Oliveira, Marlos Melo Martins, Carlos Eduardo Raymundo, Roberto de Andrade Medronho
BMC INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Marcella Cini Oliveira, Tatiana de Araujo Eleuterio, Allan Bruno de Andrade Correa, Lucas Dalsenter Romano da Silva, Renata Coelho Rodrigues, Bruna Andrade de Oliveira, Marlos Melo Martins, Carlos Eduardo Raymundo, Roberto de Andrade Medronho
Summary: This study found that older individuals of black race/skin color with heart disease or diabetes who had dyspnea or fever were more likely to die from COVID-19.
BMC INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Carlos Eduardo Raymundo, Roberto de Andrade Medronho
Summary: The study analyzed the spatial distribution of ZIKV in Rio de Janeiro, Brazil, in 2015 and 2016, and its associations with socio-environmental factors. Results showed that low income may be a risk factor for Zika occurrence in the localities, while household conditions related to adequate water supply and public sewage disposal were associated with lower ZIKV cumulative incidence.
Article
Engineering, Mechanical
Gustavo B. Libotte, Lucas dos Anjos, Regina C. C. Almeida, Sandra M. C. Malta, Renato S. Silva
Summary: Reliable data is crucial for accurately predicting epidemic dynamics, but political, economic, and social factors can lead to inconsistencies in reported data. In the case of COVID-19, underreporting of cases due to testing capacity reduction is a major source of uncertainty. To improve predictive ability, we propose strategies such as data regularization and varying compartmental model parameters over time.
NONLINEAR DYNAMICS
(2022)
Article
Public, Environmental & Occupational Health
Cristina Makarenko, Alexandre San Pedro, Natalia Santana Paiva, Jefferson Pereira Caldas Dos Santos, Roberto de Andrade Medronho, Gerusa Gibson
Summary: This study analyzes the epidemiological characteristics and spatial diffusion pattern of the largest measles epidemic in the post-elimination period in the state of Sao Paulo, Brazil. The findings indicate that males and white individuals aged 18-29 were most affected. Children and young adults were at higher risk. The unvaccinated and less educated individuals had a higher likelihood of hospitalization. The diffusion pattern followed the urban hierarchy of the main cities' regions of influence. The study suggests the need for immunization campaigns targeting young adults and investigation of clusters of vulnerable populations.
REVISTA DE SAUDE PUBLICA
(2022)
Article
Multidisciplinary Sciences
Eny Regina da Silva Queiroz, Roberto de Andrade Medronho
Summary: There was no agreement between the hotspots of the dengue fever historical series (2000-2014) and those of the emerging Zika fever and chikungunya fever (2015-2019). However, there was agreement between hotspots of the three arboviral diseases between 2015 and 2019.
Article
Multidisciplinary Sciences
Tatiana de Araujo Eleuterio, Marcella Cini Oliveira, Mariana dos Santos Velasco, Rachel de Almeida Menezes, Regina Bontorim Gomes, Marlos Melo Martins, Carlos Eduardo Raymundo, Roberto de Andrade Medronho
Summary: This study described the profile of adult patients in the state of Rio de Janeiro and analyzed the predictors of death from severe acute respiratory syndrome (SARS) due to COVID-19. The results showed that factors such as male sex, old age, low oxygen saturation, respiratory distress, chronic kidney and neurological diseases, immunosuppression, and use of ventilatory support were associated with death.
Article
Multidisciplinary Sciences
Carlos Eduardo Raymundo, Marcella Cini Oliveira, Tatiana de Araujo Eleuterio, Ednei Cesare de Arruda Santos Junior, Marcele Goncalves da Silva, Suzana Rosa Andre, Ana Ines Sousa, Roberto de Andrade Medronho
Summary: This study evaluated the spatial-temporal dynamics of COVID-19 incidence, mortality, and case fatality rates in Brazilian municipalities and their associations with social determinants. The findings showed that COVID-19 incidence and mortality decreased in municipalities that most benefited from cash transfer programs and had better social development. Municipalities with a higher proportion of non-whites had a higher risk of becoming ill and dying from the disease.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Luciane Almeida Amado, Wagner Luis da Costa Nunes Pimentel Coelho, Arthur Daniel Rocha Alves, Vanessa Cristine de Souza Carneiro, Otacilio da Cruz Moreira, Vanessa Salete de Paula, Andreza Salvio Lemos, Larissa Araujo Duarte, Elisa Gouvea Gutman, Fabricia Lima Fontes-Dantas, Joao Paulo da Costa Goncalves, Carlos Henrique Ferreira Ramos, Carlos Henrique Ferreira Ramos Filho, Marta Guimaraes Cavalcanti, Marisa Pimentel Amaro, Rafael Lopes Kader, Roberto de Andrade Medronho, Dmitry Jose de Santana Sarmento, Soniza Vieira Alves-Leon
Summary: Since the declaration of COVID-19 as a pandemic, Brazil has been severely affected. The second wave of COVID-19, caused by a new SARS-CoV-2 variant, has led to an increase in severe cases and a higher need for invasive respiratory support. Laboratory biomarkers related to various bodily functions were significantly associated with severe COVID-19.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Cristina Makarenko, Alexandre San Pedro, Natalia Santana Paiva, Reinaldo Souza-Santos, Roberto de Andrade Medronho, Gerusa Gibson
Summary: This study analyzed the occurrence of measles clusters and associated factors in the largest epidemic in the State of S??o Paulo, Brazil in 2019. The study found that sociosanitary and care factors, as well as spatial effects, have an impact on measles outbreaks. The findings emphasize the importance of strengthening measles surveillance actions, especially in socially vulnerable areas.
CADERNOS DE SAUDE PUBLICA
(2022)
Article
Multidisciplinary Sciences
Gustavo Barbosa Libotte, Lucas dos Anjos, Regina Celia Cerqueira de Almeida, Sandra Mara Cardoso Malta, Roberto de Andrade Medronho
Summary: In Brazil, vaccination has been delayed due to political and ideological factors, leading to mistrust and scepticism over vaccines. A study found that if vaccination had started 30 days earlier and vaccination rates had been increased, approximately 31,657 deaths could have been avoided. However, the slow pace of vaccination and low demand for the second dose could result in a resurgence of cases in early 2022, making it challenging to maintain a high vaccination rate and adherence to the second dose.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
Article
Public, Environmental & Occupational Health
Eny Regina da Silva Queiroz, Roberto de Andrade Medronho
Summary: The study examined the spatial distribution of dengue, Zika and chikungunya cases in Rio de Janeiro, Brazil, and found distinct patterns for each disease. It revealed negative spatial correlations between the incidence rates of these diseases and social development index and mean income, while identifying a positive relationship between urban areas and chikungunya incidence rates.
EPIDEMIOLOGY AND INFECTION
(2021)
