Article
Biology
Yi-Chia Shan, Wei Fang, Jih-Huah Wu
Summary: A feasible and integrated system was proposed to measure and affect the autonomic nervous system (ANS) status. The test results show that stimulating the Neiguan (PC6) acupoint can inhibit the sympathetic nervous system (SNS), while stimulating the Shenmen (HT7) acupoint can activate the SNS.
Article
Orthopedics
T. D. Yeater, J. Zubcevic, K. D. Allen
Summary: The study aimed to evaluate autonomic nervous system shifts in rat knee joint injury and osteoarthritis (OA) models. The results showed that injured animals had a slower heart rate during low activity and mechanical stimuli caused an immediate decrease in heart rate and blood pressure in all groups. Furthermore, the damaged groups exhibited a larger drop in heart rate following pharmacological stimulation. These findings provide preliminary evidence of potential functional shifts in the autonomic nervous system in models of joint injury and OA.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Engineering, Biomedical
Thais Marques da Silva, Carlos Alberto Aguiar Silva, Helio Cesar Salgado, Rubens Fazan Jr, Luiz Eduardo Virgilio Silva
Summary: The study investigated the influence of the autonomic nervous system on heart rate fragmentation (HRF) in rats. Results showed that sympathetic and parasympathetic influences similarly decrease HRF, with parasympathetic control markedly affecting the type of inflection points. Further studies are needed to explore the role of the autonomic nervous system in diseases marked by autonomic imbalance.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Article
Psychology, Experimental
Berge Osnes, Simen R. Berrefjord, Pauline G. Poless, Christine Sigrist, Julian Koenig, Lin Sorensen
Summary: Most people tend to overstate positive aspects of their experiences, while some people have attenuated attention for negative information. This dispositional tendency is especially important for emotion regulation and can influence the intensity of later stages of emotional experiences. The current study investigated whether a positivity or negativity bias in processing ambiguous facial expressions would predict high or lower heart rate variability (HRV) in a healthy sample.
Review
Medicine, General & Internal
J. P. Ginsberg, Karthik Raghunathan, Gabriel Bassi, Luis Ulloa
Summary: This article reviews clinical-experimental considerations and an approach to understanding the autonomic basis of improved surgical outcomes using Perioperative Music Medicine (PMM). The relationship between Music Medicine (MM) and autonomic nervous system (ANS) function is discussed, as well as the potential effects of MM on ANS, pain, and emotional regulation and dysregulation. The proposed plan aims to operationalize the study of mechanisms mediating the effects of MM in orthopedic surgery perioperative settings.
FRONTIERS IN MEDICINE
(2022)
Article
Psychology, Applied
Wei-Ju Chen, Hanna B. Johnson, Alese M. Nelson, Raymond Fleming
Summary: Studies have shown that generalized physiological arousal can enhance emotional experience for different emotions, and specific patterns of physiological reactivity may be associated with different emotions. This study examined the effects of generalized arousal on emotional experience and the physiological responses to positive and negative emotions. The results found that standing during the videos increased emotional experience, and physiological reactivity differed between positive and negative emotions.
Article
Psychology, Biological
Dalbyeol Bae, Jacob J. L. Matthews, J. Jean Chen, Linda Mah
Summary: In this study, the impact of manipulating exhalation to inhalation ratio (E:I) on heart rate variability (HRV) was examined. The findings suggest that a longer exhalation relative to inhalation, without altering breathing rate, acutely increased HRV metrics, pointing towards an enhancement of cardiac vagal tone.
Article
Psychology, Biological
Alessia Baccarani, Sophie Donnadieu, Sonia Pellissier, Renaud Brochard
Summary: Several studies have found that both music and odor have relaxing effects on the autonomic nervous system (ANS) when presented separately. A new study examined the effects of music and odor presented together on physiological recovery after cognitive stress. The study found that while music and odor separately had relaxing effects on ANS, their combination did not show any beneficial effect on ANS indexes after stress.
Review
Neurosciences
Alexane Tournier, Michael Beacom, Jenny A. Westgate, Laura Bennet, Charles Garabedian, Austin Ugwumadu, Alistair J. Gunn, Christopher A. Lear
Summary: The interpretation of FHR patterns is crucial for monitoring fetal well-being during labor, and changes in FHR variability (FHRV) have been considered an indication of fetal compromise. However, there is a lack of systematic evidence to support this observation. This review examines the potential pathways controlling FHRV during labor-like hypoxia and suggests that the parasympathetic system becomes the sole regulator of FHRV once FHR decelerations occur.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Psychology, Biological
Melodee Mograss, Emmanuel Frimpong, Franck Vilcourt, Florian Chouchou, Tehila Zvionow, Thien Thanh Dang-Vu
Summary: Recent evidence suggests that the autonomic nervous system plays a role in memory consolidation during sleep. This study found that fluctuations in cardiac autonomic activity following exercise may influence memory processes. Acute exercise attenuates parasympathetic activity and alters the relationship between memory and cardiac autonomic activity.
Article
Neurosciences
Branislav Milovanovic, Vlado Djajic, Dragana Bajic, Aleksandra Djokovic, Tatjana Krajnovic, Sladjana Jovanovic, Antonija Verhaz, Pedja Kovacevic, Miodrag Ostojic
Summary: This study found that autonomic dysfunction, including sympathetic, parasympathetic, or both, may occur in COVID-19 patients in the early phase of infection, with significantly higher proportions in the severe and mild groups compared to healthy controls. Therefore, cardiovascular autonomic neuropathy should be taken into consideration in the assessment of COVID-19 patients.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Nutrition & Dietetics
Louise Fritsche, Julia Hartkopf, Julia Hummel, Dorina S. Loeffler, Hajime Yamazaki, Hans-Ulrich Haering, Andreas Peter, Andreas L. Birkenfeld, Robert Wagner, Andreas Fritsche, Hubert Preissl, Martin Heni
Summary: Maternal metabolism and gestational weight gain are associated with offspring autonomic nervous system function. Children of mothers with low gestational weight gain have lower parasympathetic tone. The presence of gestational diabetes may affect this association.
Article
Environmental Sciences
Minna Tang, Yu He, Xiaochun Zhang, Huichu Li, Chang Huang, Cuiping Wang, Ya Gao, Yinliang Li, Haidong Kan, Jialu Hu, Renjie Chen
Summary: The study found that temperature variability is negatively associated with heart rate variability, especially on the same day. The exposure-response relationships were almost linear for most parameters. The increase in temperature variability is significantly associated with the decrease in heart rate variability, with females being more affected.
ENVIRONMENTAL RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Angelica Carandina, Giulia Lazzeri, Davide Villa, Alessio Di Fonzo, Sara Bonato, Nicola Montano, Eleonora Tobaldini
Summary: Ischemic stroke is a major global cause of death and disability, with recent research focusing on the bidirectional relationship between autonomic nervous system dysfunction and acute ischemic stroke to identify prognostic factors and potential therapeutic approaches such as vagus nerve stimulation. Preclinical studies have shown promising results in terms of neuroprotection and therapeutic possibilities, indicating the potential of neuromodulation as a first-line therapeutic approach in the early management of stroke.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Engineering, Biomedical
Javier Milagro, Lorena Soto-Retes, Jordi Giner, Carolina Varon, Pablo Laguna, Raquel Bailon, Vicente Plaza, Eduardo Gil
Summary: This study evaluated the potential of noninvasive autonomic activity assessment as a tool for stratifying asthmatic patients. The results showed similar classification performance using HRV features compared to clinical features, supporting the usefulness of HRV assessment for asthma control stratification and objective self-monitoring.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Article
Clinical Neurology
Cinthia Terroba-Chambi, Veronica Bruno, Daniel E. Vigo, Marcelo Merello
Summary: This study aimed to evaluate the relationship between HRV and falls in HD patients. The observed HRV pattern is consistent with a higher sympathetic prevalence associated with a higher RoF. Reduced parasympathetic HRV values predict recurrent falling in this patient population at 6-month follow-up.
CLINICAL AUTONOMIC RESEARCH
(2021)
Article
Anesthesiology
Veit Mylius, Santiago Perez Lloret, Rubens G. Cury, Manoel J. Teixeira, Victor R. Barbosa, Egberto R. Barbosa, Larissa Moreira, Clarice Listik, Ana M. Fernandes, Diogo de Lacerda Veiga, Julio Barbour, Nathalie Hollenstein, Matthias Oechsner, Julia Walch, Florian Brugger, Stefan Hagele-Link, Serafin Beer, Alexandra Rizos, Kallol Ray Chaudhuri, Didier Bouhassira, Jean-Pascal Lefaucheur, Lars Timmermann, Roman Gonzenbach, Georg Kagi, Jens Carsten Moeller, Daniel Ciampi de Andrade
Summary: This study developed a framework to differentiate Parkinson disease (PD)-related pain from unrelated pain, classifying PD-related pain into different types based on mechanistic pain descriptors. The PD-Pain Classification System (PD-PCS) was found to be a valid and reliable tool for distinguishing PD-related pain from unrelated pain.
Article
Engineering, Biomedical
Jose Gallardo, Giannina Bellone, Santiago Plano, Daniel Vigo, Marcelo Risk
Summary: This study aimed to use HRV signals to determine the presence of single-night sleep deprivation in healthy subjects, with results indicating that the SD21 index derived from the Poincare plot was the only HRV index that showed differences between deprived and non-deprived subjects.
JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING
(2021)
Article
Psychology, Applied
Camila Tortello, Agustin Folgueira, Michel Nicolas, Juan Manuel Cuiuli, German Cairoli, Valeria Crippa, Marta Barbarito, Carolina Abulafia, Diego Andres Golombek, Daniel Eduardo Vigo, Santiago Andres Plano
Summary: Working in extreme environments like Antarctica requires a wide range of cognitive, psychological, and social competences. This study found that social support and mature coping strategies are important for recovery from stress among crew members at the Belgrano II Argentine Antarctic Station, highlighting the significance of interpersonal relationships in psychological adjustment to isolation and extreme environments.
Article
Obstetrics & Gynecology
Edgardo G. Szyld, Adriana Aguilar, Santiago Perez Lloret, Amorina Pardo, Jorge Fabres, Adriana Castro, Douglas Dannaway, Purnahamsi V. Desai, Carola Capelli, Clara H. Song, Diego Enriquez, Demian Szyld
Summary: Video self-instruction is effective in teaching novice providers positive pressure ventilation skills and theoretical knowledge, but may not be comprehensive enough for mastery of basic neonatal resuscitation in a simulation environment.
JOURNAL OF PERINATOLOGY
(2021)
Article
Clinical Neurology
V Mylius, S. Perez Lloret, C. S. Brook, M. T. Krueger, S. Haegele-Link, R. Gonzenbach, J. Kassubek, S. Bohlhalter, J. P. Lefaucheur, L. Timmermann, G. Kaegi, F. Brugger, D. Ciampi de Andrade, J. C. Moeller
Summary: This study developed a new Parkinson's disease pain classification system (PD-PCS) and translated the corresponding questionnaire into German. The initial validation showed that the questionnaire had high validity and moderate reliability, facilitating the diagnosis and treatment of PD-associated pain.
Letter
Anesthesiology
Veit Mylius, Santiago Perez Lloret, Daniel Ciampi de Andrade
Article
Immunology
Abdallah Alami, Daniel Krewski, Donald Mattison, Kumanan Wilson, Christopher A. Gravel, Paul J. Villeneuve, Patrick J. Farrell, James A. G. Crispo, Santiago Perez-Lloret
Summary: There have been reports of rare complications, such as myocarditis and pericarditis, following mRNA COVID-19 vaccinations among young adults. A higher-than-expected reporting rate of these complications has been observed, particularly after the second dose, in males compared to females, and with decreasing risk with age. Confirmatory epidemiological studies should be conducted due to the limitations of passive surveillance data.
Review
Clinical Neurology
Debora Loureiro, Rodrigo Bilbao, Sofia Bordet, Lina Grasso, Matilde Otero-Losada, Francisco Capani, Osvaldo J. J. Ponzo, Santiago Perez-Lloret
Summary: Orthostatic hypotension is significantly associated with minimal cognitive impairment and dementia in patients with Parkinson's disease, especially in women and those without hypertension.
NEUROLOGICAL SCIENCES
(2023)
Correction
Clinical Neurology
Debora Loureiro, Rodrigo Bilbao, Sofia Bordet, Lina Grasso, Matilde Otero-Losada, Francisco Capani, Osvaldo J. Ponzo, Santiago Perez-Lloret
NEUROLOGICAL SCIENCES
(2023)
Article
Clinical Neurology
Clarice Listik, Eduardo Listik, Flavia de Paiva Santos Rolim, Denise Maria Meneses Cury Portela, Santiago Perez Lloret, Natalia Rebeca de Alves Araujo, Pedro Rubens Araujo Carvalho, Graziele Costa Santos, Joao Carlos Papaterra Limongi, Francisco Cardoso, Veit Mylius, Florian Brugger, Ana Mercia Fernandes, Egberto Reis Barbosa, Manoel Jacobsen Teixeira, Henrique Ballalai Ferraz, Sarah Teixeira Camargos, Rubens Gisbert Cury, Daniel de Ciampi de Andrade
Summary: The aim of this study was to develop a classification and scoring system for chronic pain (CP) in dystonia. The results showed that the developed Dystonia-Pain Classification System (Dystonia-PCS) is a reliable tool for categorizing and quantifying CP impact in dystonia and can help improve clinical trial design and pain management in patients with this disorder.
MOVEMENT DISORDERS
(2023)
Article
Multidisciplinary Sciences
Daniel Perez-Chada, Sergio Arias Bioch, Daniel Schonfeld, David Gozal, Santiago Perez-Lloret
Summary: This study investigated the relationship between screen time use, sleep characteristics, daytime somnolence, and academic performance in school-aged adolescents. The survey was conducted on 1,257 adolescents aged 12 to 18 from 52 schools in urban or suburban areas of Argentina. The results showed that screen use had a negative impact on nighttime sleep, daytime somnolence, and academic performance among adolescents. The findings emphasize the need for educational public campaigns to promote healthy sleep and reduce screen exposure in this population.
Article
Neurosciences
Guenson Chevalier, Lucas Udovin, Matilde Otero-Losada, Sofia Bordet, Francisco Capani, Sheng Luo, Christopher G. Goetz, Santiago Perez-Lloret
Summary: This study explores the genetic basis of Neurogenic Orthostatic Hypotension (NOH) in Parkinson's disease (PD) and investigates its effects on gene expression and metabolic/signaling pathways. The results show that certain genetic polymorphisms affect gene expression associated with the autonomic nervous system and influence metabolic/signaling pathways related to NOH. These findings provide new insights into the pathophysiology of NOH in PD and may suggest potential targets for future therapies.
Article
Medicine, General & Internal
Abdallah Alami, Paul J. J. Villeneuve, Patrick J. J. Farrell, Donald Mattison, Nawal Farhat, Nisrine Haddad, Kumanan Wilson, Christopher A. A. Gravel, James A. G. Crispo, Santiago Perez-Lloret, Daniel Krewski
Summary: This study analyzed reports from the Vaccine Adverse Events Reporting System (VAERS) and found safety signals for myocarditis and pericarditis following mRNA COVID-19 vaccination, especially in younger individuals. The study focused on children as young as 6 months old. The results showed a higher reporting rate of myocarditis and pericarditis after the primary vaccine series, particularly in males and mainly after the second dose. However, the reporting cases decreased with booster doses, and no significant signals were detected after the fourth or fifth doses. In children and young adults, there were notable age and sex differences in the reporting of myocarditis and pericarditis cases. Males in the 12-17 and 18-24-year-old age groups had the highest number of cases, with significant signals for both males and females after the second dose. Additionally, an increased reporting of cardiovascular symptoms such as chest pain and dyspnea was identified, which increased with age and were reported more frequently than myocarditis and pericarditis.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Neurosciences
Santiago Perez-Lloret, Guenson Chevalier, Sofia Bordet, Hanny Barbar, Francisco Capani, Lucas Udovin, Matilde Otero-Losada
Summary: Patients with Parkinson's Disease (PD) are more likely to experience REM sleep behavior disorder (RBD) compared to healthy controls. The presence of certain genetic mutations increases the risk of developing RBD in PD patients, but genetic mutations alone are not sufficient for the development of RBD.
