Review
Plant Sciences
Theysshana Visuvanathan, Leslie Thian Lung Than, Johnson Stanslas, Shu Yih Chew, Shalini Vellasamy
Summary: Fenugreek is a medicinal plant with therapeutic characteristics that has been utilized since ancient times. It contains various secondary metabolites which have been shown to have therapeutic effects through animal and clinical studies. Fenugreek has the potential to be used as a credible medicinal plant for deriving new drugs.
Article
Food Science & Technology
Faiza Shams, Ayesha Azeem, Ammara Shams, Abdul Tawab, Sidra Rehman, Somayya Tariq, Noreen Latief, Bushra Ijaz
Summary: The study demonstrates that Trigonella foenum-graecum flavonoid-rich leaf extract has anti-fibrotic potential in CCl4-induced hepatic fibrosis in mice by improving hepatocyte architecture, reducing collagen deposition, downregulating fibrotic markers, and regulating NF-KB and TGF-β/Smad signaling pathways.
Article
Food Science & Technology
Neetu Singh, Surender Singh Yadav, Sanjiv Kumar, Balasubramaniam Narashiman
Summary: Trigonella foenum-graecum is widely used for culinary and clinical purposes. It has pharmacological effects attributed to its diverse phytoconstituents. Nanoparticle synthesis can enhance its pharmacological efficacy. Clinical studies have validated its therapeutic potential in diabetes and reproductive health.
Article
Biochemistry & Molecular Biology
Hina Fatima, Muhammad Shahid, Chris Pruitt, Meredith A. Pung, Paul J. Mills, Muhammad Riaz, Rizwan Ashraf
Summary: This study evaluated the antioxidant and anti-inflammatory potential of hydroethanolic extract of T. foenum-graecum seeds. The extract exhibited significant antioxidant activity and was non-toxic to human and murine cells. It also showed a concentration-dependent reduction in inflammatory markers and improved antioxidant levels against oxidative stress. The hydroethanolic extract of T. foenum-graecum is a potential source of phenolic compounds with antioxidant and anti-inflammatory properties.
Article
Plant Sciences
Wiem Mnafgui, Valeria Rizzo, Giuseppe Muratore, Hicham Hajlaoui, Amine Elleuch
Summary: This study evaluated the effects of lead on the morphological and phytochemical responses of fenugreek. It found that fenugreek can be used for lead phytoremediation and remains safe for consumption after lead treatments.
Article
Biochemistry & Molecular Biology
Avinash Kumar, Vinay Kumar Singh, Arvind M. Kayastha
Summary: This study determined the three-dimensional structure of fenugreek α-amylase using homology modeling and analyzed its molecular basis and mode of action through molecular dynamics simulations and molecular docking. The study identified functional groupings and binding interactions between the enzyme and its substrate maltose. The research provides valuable insights into the atomic-level molecular underpinnings of α-amylase interaction with maltose.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Environmental Sciences
Javed Ahmad, Md Amjad Beg, Arlene A. Ali, Asma A. Al-Huqail, M. Irfan Qureshi
Summary: Arsenic contamination has detrimental effects on the physiology, growth, and yield of Trigonella foenum-graecum by increasing oxidative stress and decreasing photosynthetic parameters. The plant responds to arsenic toxicity by enhancing antioxidant potential and accumulating specific metabolites.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Engineering, Chemical
Manal A. Awad, Promy Virk, Awatif A. Hendi, Khalid Mustafa Ortashi, Najla Almasoud, Taghrid S. Alomar
Summary: As the human population grows, the demand for clean water is increasing. This study synthesized AgNPs using an aqueous extract of Trigonella foenum-graecum seeds. The AgNPs showed potential wastewater remediation efficacy, antimicrobial activity, and photodegradative activity. Therefore, biogenically synthesized AgNPs offer a prospective potential for use in wastewater remediation strategies.
Review
Plant Sciences
Pushpa Ruwali, Niharika Pandey, Khusboo Jindal, Rahul Vikram Singh
Summary: Fenugreek, a herb with medicinal and nutraceutical values, contains various bioactive compounds and possesses antibiotic, antioxidant, anti-carcinogenic properties, as well as the ability to control hyperglycemia in diabetic patients.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Chemistry, Applied
Thierry Hellebois, Claire Gaiani, Jennyfer Fortuin, Alexander Shaplov, Christos Soukoulis
Summary: Cryotropic gelation is a common method to design novel hydrogels with multifaceted functionalities. This study focused on the formation of physically crosslinked hydrogels using highly galactosyl-substituted galactomannans like fenugreek and alfalfa gum via cryogenic processing. Results showed that alfalfa gum-based cryogels had higher elasticity and stiffness compared to fenugreek counterparts, and blending with locust bean gum enhanced the mechanical properties without altering microstructural aspects significantly.
CARBOHYDRATE POLYMERS
(2021)
Article
Environmental Sciences
Javed Ahmad, Rubina Yasmeen, Mohammad Irfan, Asma A. Al-Huqail, Mohammad Irfan Qureshi
Summary: Traces of arsenic in vegetables and crops cultivated in arsenic-polluted soils are a global concern due to its carcinogenic properties and harmful effects on the food chain. This study focused on the accumulation and defense mechanisms of fenugreek plants exposed to arsenic stress. The findings showed increased oxidative stress and DNA damage at higher arsenic concentrations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Plant Sciences
Eun-Young Kim, Hoyeon Park, Eom Ji Kim, Seung Hoon Lee, Jun Won Choi, Jonghyun Kim, Hyuk-Sang Jung, Youngjoo Sohn
Summary: This study demonstrates the efficacy of Trigonella foenum-graecum Linne (TFG) in alleviating PM-induced inflammatory response in bronchial epithelial cells and an animal model of asthma exacerbation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Reda E. Abdelhameed, Arafat Abdel Hamed Abdel Latef, Rania S. Shehata
Summary: Foliar application of salicylic acid improves salt tolerance of fenugreek plants by increasing chlorophyll content index and reducing malondialdehyde content, while promoting accumulation of proline, total phenolics, and flavonoids. Additionally, it enhances total free amino acids and shikimic acid, and activates antioxidant enzymes such as ascorbate peroxidase, peroxidase, polyphenol oxidase, and catalase.
Article
Agricultural Engineering
Hamzeh Amiri, Mohammad Hossein Banakar, Gholam Hassan Ranjbar, Mohammad Reza Sarafraz Ardakani, Mahtab Omidvari
Summary: The objective of this study was to investigate the effect of plant growth regulators on fenugreek under saline conditions. The results showed that appropriate concentrations of spermidine and methyl jasmonate could significantly mitigate the adverse effects of salinity stress and improve the growth of fenugreek.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Engineering, Electrical & Electronic
Manal A. Awad, Awatif A. Hendi, Khalid Mustafa Ortashi, Batool Alzahrani, Dina Soliman, Amnah Alanazi, Wadha Alenazi, Rasha Mohammed Taha, Rasha Ramadan, Maha El-Tohamy, Najla AlMasoud, Taghrid S. Alomar
Summary: Biogenic synthesis of nanoparticles using fenugreek is an environmentally friendly and safe method with potential biomedical applications. The synthesized silver nanoparticles showed stable properties and exhibited efficient photocatalytic and antibacterial activities, making them promising for various practical uses. The characterization of nanoparticles using UV-vis spectroscopy and electron microscopes confirmed their properties, showing great potential for further research and development in nanoscience.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Article
Immunology
Gil Benedek, Jun Zhang, Sheetal Bodhankar, Ha Nguyen, Gail Kent, Kelley Jordan, Dustin Manning, Arthur A. Vandenbark, Halina Offner
JOURNAL OF NEUROIMMUNOLOGY
(2016)
Article
Environmental Sciences
Anwesha A. Mukherjee, Amit D. Kandhare, Subhash L. Bodhankar
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2017)
Article
Immunology
Urmila U. Tambewagh, Amit D. Kandhare, Varsha S. Honmore, Parag P. Kadam, Vijay M. Khedkar, Subhash L. Bodhankar, Supada R. Rojatkar
INTERNATIONAL IMMUNOPHARMACOLOGY
(2017)
Review
Pharmacology & Pharmacy
Mohammad Adil, Rashid Ali Khan, Abul Kalam, Shiva Kumar Venkata, Amit Dattatraya Kandhare, Pinaki Ghosh, Manju Sharma
PHARMACOLOGICAL REPORTS
(2017)
Article
Biotechnology & Applied Microbiology
Shrey Bodhankar, Minakshi Grover, Sunaina Hemanth, Gopal Reddy, Shaik Rasul, Sushil Kumar Yadav, Suseelendra Desai, Manjunath Mallappa, Maheswari Mandapaka, Ch. Srinivasarao
Article
Biotechnology & Applied Microbiology
Shrey Bodhankar, Minakshi Grover, Sunaina Hemanth, Gopal Reddy, Shaik Rasul, Sushil Kumar Yadav, Suseelendra Desai, Manjunath Mallappa, Maheswari Mandapaka, Ch. Srinivasarao
Article
Urology & Nephrology
Anwesha A. Mukherjee, Amit D. Kandhare, Subhash L. Bodhankar
Article
Food Science & Technology
Jian Cui, Gang Wang, Amit D. Kandhare, Anwesha A. Mukherjee-Kandhare, Subhash L. Bodhankar
FOOD AND CHEMICAL TOXICOLOGY
(2018)
Article
Anatomy & Morphology
Amit D. Kandhare, Urmila M. Aswar, Vishwaraman Mohan, Prasad A. Thakurdesai
ANATOMY & CELL BIOLOGY
(2017)
Article
Medicine, Research & Experimental
Anwesha A. Mukherjee, Amit D. Kandhare, Supada R. Rojatkar, Subhash L. Bodhankar
BIOMEDICINE & PHARMACOTHERAPY
(2017)
Article
Medicine, Research & Experimental
Mohammad Adil, Mohd Nizam Mansoori, Divya Singh, Amit Dattatraya Kandhare, Manju Sharma
BIOMEDICINE & PHARMACOTHERAPY
(2017)
Review
Biochemistry & Molecular Biology
Amit D. Kandhare, Anwesha Mukherjee, Subhash L. Bodhankar
CHEMICO-BIOLOGICAL INTERACTIONS
(2017)
Article
Pharmacology & Pharmacy
Amit D. Kandhare, Subhash Laxmanrao Bodhankar, Vishwaraman Mohan, Prasad A. Thakurdesai
JOURNAL OF PHARMACY AND BIOALLIED SCIENCES
(2017)
Article
Biology
Amit D. Kandhare, Anwesha A. Mukherjee, Subhash L. Bodhankar
Article
Biology
Wenbin Li, Amit D. Kandhare, Anwesha A. Mukherjee, Subhash L. Bodhankar
