The epigenome of synovial fibroblasts: an underestimated therapeutic target in rheumatoid arthritis

Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis

(2012) Adelheid Korb-Pap et al.   ANNALS OF THE RHEUMATIC DISEASES

DNA methylome signature in rheumatoid arthritis

(2012) Kazuhisa Nakano et al.   ANNALS OF THE RHEUMATIC DISEASES

Tumor Necrosis Factor α-Induced MicroRNA-18a Activates Rheumatoid Arthritis Synovial Fibroblasts Through a Feedback Loop in NF-κB Signaling

(2012) Michelle Trenkmann et al.   ARTHRITIS AND RHEUMATISM

Epigenetic contributions in the development of rheumatoid arthritis

(2012) Kerstin Klein et al.   ARTHRITIS RESEARCH & THERAPY

Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis

(2011) M. Trenkmann et al.   ANNALS OF THE RHEUMATIC DISEASES

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

(2011) Aleksander M Grabiec et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

(2011) Emmanuel Karouzakis et al.   ARTHRITIS AND RHEUMATISM

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts

(2011) E Karouzakis et al.   GENES AND IMMUNITY

MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis

(2011) M. Kurowska-Stolarska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation

(2010) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

Rheumatoid arthritis progression mediated by activated synovial fibroblasts

(2010) Elena Neumann et al.   TRENDS IN MOLECULAR MEDICINE

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

(2009) Emmanuel Karouzakis et al.   ARTHRITIS AND RHEUMATISM

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE