Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes

(2012) Y. T. Bryceson et al.   BLOOD

Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D

(2011) M. Meeths et al.   BLOOD

How I treat hemophagocytic lymphohistiocytosis

(2011) M. B. Jordan et al.   BLOOD

Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH

(2011) K. Zhang et al.   BLOOD

CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia

(2011) Joris M. van Montfrans et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An International Consensus Survey of Diagnostic Criteria for Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis

(2011) S. DAVI et al.   JOURNAL OF RHEUMATOLOGY

Malignancy-associated hemophagocytic lymphohistiocytosis in adults: a retrospective population-based analysis from a single center

(2011) Maciej Machaczka et al.   LEUKEMIA & LYMPHOMA

Syntaxin 11 Binds Vti1b and Regulates Late Endosome to Lysosome Fusion in Macrophages

(2011) Carolin Offenhäuser et al.   TRAFFIC

Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series

(2010) Peter A. Nigrovic et al.   ARTHRITIS AND RHEUMATISM

Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation

(2010) R. A. Marsh et al.   BLOOD

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

(2010) J. P. Schmid et al.   BLOOD

Molecular basis of familial hemophagocytic lymphohistiocytosis

(2010) V. Cetica et al.   HAEMATOLOGICA

Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases

(2010) J. Rohr et al.   HAEMATOLOGICA

IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach

(2010) P. Stepensky et al.   HAEMATOLOGICA

Using flow cytometry to screen patients for X-linked lymphoproliferative disease due to SAP deficiency and XIAP deficiency

(2010) Rebecca A. Marsh et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Treatment of Epstein-Barr Virus-related Hemophagocytic Lymphohistiocytosis (EBV-HLH); Update 2010

(2010) Shinsaku Imashuku   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis

(2010) Matthew P. Strout et al.   Nature Reviews Clinical Oncology

Viral infections associated with haemophagocytic syndrome

(2010) Nadine Rouphael Maakaroun et al.   REVIEWS IN MEDICAL VIROLOGY

Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11

(2009) Udo zur Stadt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Systemic JIA: new developments in the understanding of the pathophysiology and therapy

(2009) Sebastiaan J. Vastert et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Hemophagocytic syndrome after hematopoietic stem cell transplantation: a prospective observational study

(2009) Abderrahman Abdelkefi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

(2009) Kirsten Huck et al.   JOURNAL OF CLINICAL INVESTIGATION

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

(2009) Marjorie Côte et al.   JOURNAL OF CLINICAL INVESTIGATION

Hemophagocytic Lymphohistiocytosis: When the Immune System Runs Amok

(2009) G. Janka   KLINISCHE PADIATRIE

Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis

(2008) AnnaCarin Horne et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hemophagocytic lymphohistiocytosis as severe adverse event of antineoplastic treatment in children

(2008) H. Lackner et al.   HAEMATOLOGICA

Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3

(2008) A. Santoro et al.   HAEMATOLOGICA

Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis

(2007) Carl E. Allen et al.   PEDIATRIC BLOOD & CANCER