Article
Health Care Sciences & Services
Ji-Ah Song, Jae Woo Oh
Summary: This systematic review found that aquatic exercise-based interventions are effective for reducing pain and joint dysfunction, and improving quality of life among patients with osteoarthritis.
Review
Multidisciplinary Sciences
T. A. M. Oud, E. Lazzari, H. J. H. Gijsbers, M. Gobbo, F. Nollet, M. A. Brehm
Summary: The current literature on the effectiveness of 3D-printed orthoses for traumatic and chronic hand conditions consists of primarily small and poor quality studies. Well-designed controlled trials are needed, including patient-related outcomes, production time, and cost analyses.
Review
Rheumatology
Michelle Hall, Fiona Dobson, Ans Van Ginckel, Rachel K. Nelligan, Natalie J. Collins, Michelle D. Smith, Megan H. Ross, Esther Smits, Kim L. Bennell
Summary: This study aimed to compare the effectiveness of different types of exercise on psychological well-being in people with knee OA, and found that strengthening exercise was most beneficial for overall mental health, while strengthening exercise or mixed exercise were more beneficial for depressive symptoms than stretching exercise. No specific exercise recommendations could be made for anxiety.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2021)
Review
Rehabilitation
Chen Guang Qiu, Chun Sing Chui, Simon Kwoon Ho Chow, Wing-Hoi Cheung, Ronald Man Yeung Wong
Summary: This study assessed the effects and safety of whole-body vibration on pain, stiffness, physical function, and muscle strength in patients with knee osteoarthritis. The systematic review and meta-analysis showed that whole-body vibration with strengthening exercises had significant positive effects on pain, knee extensor muscle strength, and physical function in individuals with knee osteoarthritis. Both low-frequency and high-frequency whole-body vibration were associated with significant changes in pain, physical function, and knee extensor strength. No adverse events were reported.
JOURNAL OF REHABILITATION MEDICINE
(2022)
Review
Rehabilitation
Ana M. Idanez-Robles, Esteban Obrero-Gaitan, Rafael Lomas-Vega, Maria C. Osuna-Perez, Irene Cortes-Perez, Noelia Zagalaz-Anula
Summary: The analysis indicates that exercise therapy is effective in reducing pain and improving maximum mouth opening in patients with temporomandibular disorders.
CLINICAL REHABILITATION
(2023)
Review
Health Care Sciences & Services
Monica Sousa, Rafael Oliveira, Joao Paulo Brito, Alexandre Duarte Martins, Joao Moutao, Susana Alves
Summary: Fibromyalgia, a rheumatic disease characterized by chronic muscular pain, is treated through pharmacological interventions. This study aimed to analyze exercise programs for fibromyalgia patients and their effects. A systematic literature search identified 13 articles meeting the criteria, revealing beneficial effects of various exercise interventions in reducing symptoms and improving physical fitness and functional capacity. Combined training programs, lasting 60-90 minutes, with a low to moderate intensity, conducted three times a week, were found to be the most effective.
Review
Computer Science, Information Systems
Tianrong Chen, Calvin Kalun Or, Jiayin Chen
Summary: A systematic review and meta-analysis of randomized controlled trials found that technology-supported exercise programs can significantly improve knee pain and quality of life for individuals with knee osteoarthritis and chronic knee pain. However, the improvement in physical function was not significant. Certain technology types and program features showed potential benefits for patients.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Review
Geriatrics & Gerontology
Courtney D. Reynolds, Kaitlyn Brazier, Evelyn A. A. Burgess, Jonathan A. Golla, Jayson Le, Brenna A. Parks, Sachi O'Hoski, Marla K. Beauchamp
Summary: The study found that unstructured mobility programs in general medicine units may improve physical activity and physical function in older hospitalized patients, although the quality of evidence was low. More randomized controlled trials are needed to evaluate the effectiveness of mobility interventions, especially in terms of length of stay and quality of life.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Review
Physiology
Nuannuan Deng, Kim Geok Soh, Borhannudin Abdullah, Dandan Huang, He Sun, Wensheng Xiao
Summary: This systematic review and meta-analysis aimed to determine the effects of physical training on performance outcomes in female tennis players. The review found that existing training programs yield some favorable outcomes for female tennis players. However, further research with high methodological quality is warranted on the tailoring of specific training programs for female tennis players, and there should be more consistent measuring and reporting of data to facilitate meaningful data pooling for future meta-analyses.
FRONTIERS IN PHYSIOLOGY
(2023)
Review
Pharmacology & Pharmacy
Kohei Yamaura, Anna Laura Nelson, Haruki Nishimura, Joan C. Rutledge, Sudheer K. Ravuri, Chelsea Bahney, Marc J. Philippon, Johnny Huard
Summary: Fisetin, a natural flavonoid, shows promising pharmaceutical potential for treating or delaying the progression of osteoporosis and osteoarthritis. Studies have demonstrated the beneficial effects of fisetin on osteoporosis and osteoarthritis in preclinical and animal studies.
PHARMACOLOGICAL RESEARCH
(2022)
Review
Surgery
Thomas E. Tieman, Liron S. Duraku, Mark J. W. van der Oest, Caroline A. Hundepool, Ruud W. Selles, J. Michiel Zuidam
Summary: Joint denervation is a treatment option for chronic pain patients, with limited evidence and no significant difference in outcomes between techniques.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Review
Green & Sustainable Science & Technology
Claudio Farias-Valenzuela, Paloma Ferrero-Hernandez, Gerson Ferrari, Cristian Cofre-Bolados, Sebastian Espoz-Lazo, Sebastian Alvarez-Arangua, Adilson Marques, Pedro Valdivia-Moral
Summary: People with intellectual disabilities (ID) often face issues related to overweight, obesity, heart and metabolic diseases, and low motor development. Multicomponent physical exercise programs (MPEPs) have been found to have positive effects on physical fitness in people with ID, particularly in the areas of morphology, motor skills, muscle strength, metabolism, and cardiorespiratory health. More research is needed to understand and standardize the effects of MPEPs on other dimensions of physical fitness and utilize them as an alternative to reduce sedentary behavior in people with ID.
Review
Geriatrics & Gerontology
Hsiang-Jung Ni, Teh-Fu Hsu, Liang-Kung Chen, Hsiu-Ling Chou, Heng-Hsin Tung, Lok-Hi Chow, Yu-Chi Chen
Summary: Exercise intervention has significant benefits for older adults with muscle wasting diseases, improving body composition, muscle strength, and physical function. More well-designed large-sample-sized studies are needed to confirm the benefits of exercise intervention in this population.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2022)
Review
Oncology
Chad W. Wagoner, Jordan T. Lee, Claudio L. Battaglini
Summary: The study aimed to explore the prevalence of cancer-related fatigue (CRF) within community-based exercise programs and the overall impact of participation in these programs on CRF. The results showed that less than half of the identified programs reported CRF outcomes, with a small yet significant impact on improving CRF after exercise participation. More research is needed in this area.
SUPPORTIVE CARE IN CANCER
(2021)
Review
Engineering, Biomedical
Patricia Gabielli Vassao, Julia Parisi, Thaise Fernanda Campos Penha, Ana Beatriz Balao, Ana Claudia Muniz Renno, Mariana Arias Avila
Summary: This review found that there is controversy on the effects of PBMT associated with exercises for pain and functional capacity improvement for people with KOA, mainly due to the heterogeneity between studies in related to PBMT parameters and exercise protocols.
LASERS IN MEDICAL SCIENCE
(2021)
Article
Rheumatology
Thomas Davergne, Rikke H. Moe, Bruno Fautrel, Laure Gossec
RHEUMATOLOGY INTERNATIONAL
(2020)
Article
Rheumatology
Karen Holten, Nina Paulshus Sundlisater, Siri Lillegraven, Joseph Sexton, Lena Bugge Nordberg, Ellen Moholt, Hilde Berner Hammer, Till Uhlig, Tore K. Kvien, Espen A. Haavardsholm, Anna-Birgitte Aga
Summary: Fatigue is a common symptom in early RA patients, with a rapid and sustained reduction during treatment. Low objective disease activity and high patient global assessment at baseline were predictors of clinically relevant fatigue at 24 months.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Rheumatology
Ingrid Egeland Christensen, Siri Lillegraven, Pawel Mielnik, Gunnstein Bakland, Liz Loli, Joe Sexton, Till Uhlig, Tore K. Kvien, Sella A. Provan
Summary: The study estimated the incidence of serious infections (SIs) in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) treated with TNFi, and compared the risk of SIs between the two groups. The results showed that patients with PsA had a lower risk of SIs compared to those with RA during TNFi treatment.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Rheumatology
Pernille Steen Pettersen, Tuhina Neogi, Karin Magnusson, Alexander Mathiessen, Hilde Berner Hammer, Till Uhlig, Tore K. Kvien, Ida K. Haugen
Summary: The pathologies and symptom duration of hand osteoarthritis (OA) are related to central sensitization, with erosive hand OA potentially causing greater central sensitization. Structural and inflammatory severity are not associated with central sensitization, while symptom duration does not contribute to central sensitization.
Article
Rheumatology
Nina Paulshus Sundlisaeter, Ulf Sundin, Anna-Birgitte Aga, Joseph Sexton, Hilde Berner Hammer, Till Uhlig, Tore K. Kvien, Espen A. Haavardsholm, Siri Lillegraven
Summary: This study investigated the limiting factors of achieving ACR/EULAR Boolean remission in rheumatoid arthritis (RA) patients. Patient global assessment and tender joints were found to be the most common factors limiting remission. Although imaging inflammation levels were not elevated in patients failing to meet the criteria, the odds of using biologic disease modifying anti-rheumatic drugs (DMARDs) were higher.
Article
Rheumatology
James M. Gwinnutt, Maud Wieczorek, Andra Balanescu, Heike A. Bischoff-Ferrari, Annelies Boonen, Giulio Cavalli, Savia de Souza, Annette de Thurah, Thomas E. Dorner, Rikke Helene Moe, Polina Putrik, Javier Rodriguez-Carrio, Lucia Silva-Fernandez, Tanja Stamm, Karen Walker-Bone, Joep Welling, Mirjana Zlatkovic-Svenda, Francis Guillemin, Suzanne M. M. Verstappen
Summary: A taskforce in Europe has reviewed the literature and developed recommendations on lifestyle behaviors for rheumatic and musculoskeletal diseases. They have identified five overarching principles and 18 specific recommendations based on available evidence. The recommendations cover various lifestyle factors such as exercise, diet, weight, alcohol, smoking, and work participation.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Review
Rheumatology
James M. Gwinnutt, Maud Wieczorek, Giulio Cavalli, Andra Balanescu, Heike A. Bischoff-Ferrari, Annelies Boonen, Savia de Souza, Annette de Thurah, Thomas E. Dorner, Rikke Helene Moe, Polina Putrik, Javier Rodriguez-Carrio, Lucia Silva-Fernandez, Tanja Stamm, Karen Walker-Bone, Joep Welling, Mirjana Zlatkovic-Svenda, Francis Guillemin, Suzanne M. M. Verstappen
Summary: This paper reviews the effects of physical exercise and body weight on disease-specific outcomes in people with RMDs. Exercise interventions can result in improvements in pain and function, while increased body weight is associated with worse outcomes.
Article
Rheumatology
Hilde Berner Hammer, Silvia Rollefstad, Anne Grete Semb, Gro Jensen, Lars Fridtjof Karoliussen, L. Terslev, Espen A. Haavardsholm, Tore K. Kvien, Till Uhlig
Summary: The study found that crystal deposition in gout patients is associated with increased inflammation levels and carotid artery pathology, suggesting that crystal deposition may lead to subclinical inflammation with subsequent vascular implications. However, further longitudinal studies are needed to confirm these causal relationships.
Article
Rheumatology
T. Uhlig, L. F. Karoliussen, J. Sexton, T. K. Kvien, E. A. Haavardsholm, F. Perez-Ruiz, H. B. Hammer
Summary: This study investigates the relationship between fluctuation and change in serum urate (SU) levels and the occurrence of gout flares. The results show that fluctuations and changes in SU levels are related to gout flares, while changes between visits and reaching higher SU levels are not.
CLINICAL RHEUMATOLOGY
(2022)
Article
Rheumatology
Leanne Chen, Gregory D. Gamble, Anne Horne, Jill Drake, Anthony J. Doyle, Till Uhlig, Lisa K. Stamp, Nicola Dalbeth
Summary: This study finds that the composition of the gouty tophus changes during urate-lowering therapy, with a decrease in the urate volume and a relatively slower decrease in the soft tissue volume, which may persist.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Rheumatology
Till Uhlig, Lars F. Karoliussen, Joe Sexton, Sella Aarrestad Provan, Tore K. Kvien, Espen A. Haavardsholm, Hilde Berner Hammer
Summary: This study explored the longitudinal changes and predictors of work productivity in patients with gout. The results showed that work productivity and activity impairment improved during the first few months of treatment and remained stable at 1 and 2 years. Comorbidities and concerns about medication were associated with worse work impairment and activity impairment.
Article
Rheumatology
T. Uhlig, L. F. Karoliussen, J. Sexton, T. K. Kvien, E. A. Haavardsholm, W. J. Taylor, H. B. Hammer
Summary: This longitudinal study aimed to determine changes in beliefs about medicines during intervention with urate-lowering therapy (ULT). The study found that patients taking ULT gradually increased their beliefs in the necessity of medication and reduced concerns, but this improvement was unrelated to treatment outcomes.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
(2023)
Article
Medicine, General & Internal
Mari Nilsen Skinnes, Rikke Helene Moe, Thomas Johansen, Peter Solvoll Lyby, Kjersti Dahl, Idun Eid, Tor Christian Fagertun, Andreas Habberstad, Tonje Jossie Johnsen, Ingvild Kjeken, Mari Klokkerud, Anita Dyb Linge, Anne Dorte Lyken, Anders Orpana, Tarja Rajalahti, Ross Wilkie, Till Uhlig
Summary: The study found that a multidisciplinary rehabilitation program led to a significant increase in work ability. High self-perceived health was associated with higher work ability at 12 months, while being married or cohabiting, having more comorbidities, and experiencing medium baseline pain intensity were associated with lower work ability. There were no significant differences in work ability between participants receiving occupational and standard rehabilitation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Rheumatology
Geir Smedslund, Annie Martina Kotar, Till Uhlig
Summary: This study aimed to summarize the effects and usage of non-pharmacological and pharmacological treatments for sarcoidosis with musculoskeletal manifestations. The study identified 11 relevant studies, but none had a control group. Results showed a high proportion of patients received corticosteroids, NSAIDs, and other pharmacological treatments, while the use of non-pharmacological treatments was minimal. The study highlights the need for further research, particularly randomized clinical trials, to evaluate the treatment effects for sarcoidosis patients with musculoskeletal manifestations.
RHEUMATOLOGY INTERNATIONAL
(2022)
Article
Rheumatology
Till Uhlig, Lars F. Karoliussen, Joe Sexton, Tore K. Kvien, Espen A. Haavardsholm, Fernando Perez-Ruiz, Hilde Berner Hammer
Summary: The study found that gout flares were frequent in patients undergoing a treat-to-target urate-lowering therapy strategy, especially in the first year and months 3-6, but were much less frequent in the second year. Baseline crystal depositions were important predictors of flares over 2 years, supporting early initiation of urate-lowering therapy in the disease course.
ARTHRITIS RESEARCH & THERAPY
(2022)