Fitness Impaired Drug Resistant HIV-1 Is Not Compromised in Cell-to-Cell Transmission or Establishment of and Reactivation from Latency

Resistance mutations against dolutegravir in HIV integrase impair the emergence of resistance against reverse transcriptase inhibitors

(2014) Maureen Oliveira et al.   AIDS

Integrase strand transfer inhibitors in the management of HIV-positive individuals

(2014) Thibault Mesplède et al.   ANNALS OF MEDICINE

The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness

(2014) Melissa Wares et al.   Retrovirology

HIV cure research: Advances and prospects

(2014) Caroline P. Passaes et al.   VIROLOGY

Transcriptional control of HIV latency: Cellular signaling pathways, epigenetics, happenstance and the hope for a cure

(2014) Uri Mbonye et al.   VIROLOGY

Highly Active Antiretroviral Therapies Are Effective against HIV-1 Cell-to-Cell Transmission

(2014) Luis M. Agosto et al.   PLoS Pathogens

From reactivation of latent HIV-1 to elimination of the latent reservoir: The presence of multiple barriers to viral eradication

(2013) Liang Shan et al.   BIOESSAYS

What if HIV were unable to develop resistance against a new therapeutic agent?

(2013) Mark A Wainberg et al.   BMC Medicine

The immunological synapse: the gateway to the HIV reservoir

(2013) Deanna A. Kulpa et al.   IMMUNOLOGICAL REVIEWS

A cohort study of treatment-experienced HIV-1-infected patients treated with raltegravir: factors associated with virological response and mutations selected at failure

(2013) Anne-Geneviève Marcelin et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Latent HIV-1 Can Be Reactivated by Cellular Superinfection in a Tat-Dependent Manner, Which Can Lead to the Emergence of Multidrug-Resistant Recombinant Viruses

(2013) D. A. Donahue et al.   JOURNAL OF VIROLOGY

Dolutegravir versus raltegravir in antiretroviral-experienced, integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING study

(2013) Pedro Cahn et al.   LANCET

Protease inhibitors effectively block cell-to-cell spread of HIV-1 between T cells

(2013) Boghuma Titanji et al.   Retrovirology

Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure

(2013) Thibault Mesplède et al.   Retrovirology

Multiple proviral integration events after virological synapse-mediated HIV-1 spread

(2013) Rebecca A. Russell et al.   VIROLOGY

Eradication of HIV and Cure of AIDS, Now and How?

(2013) Jielin Zhang et al.   Frontiers in Immunology

Emerging patterns and implications of HIV-1 integrase inhibitor resistance

(2012) Anna Maria Geretti et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Antiretroviral Agents Effectively Block HIV Replication after Cell-to-Cell Transfer

(2012) Marc Permanyer et al.   JOURNAL OF VIROLOGY

The Viral Protein Tat Can Inhibit the Establishment of HIV-1 Latency

(2012) D. A. Donahue et al.   JOURNAL OF VIROLOGY

HIV-infected T cells are migratory vehicles for viral dissemination

(2012) Thomas T. Murooka et al.   NATURE

Resistance to HIV integrase inhibitors

(2012) Thibault Mesplède et al.   Current Opinion in HIV and AIDS

The development of novel HIV integrase inhibitors and the problem of drug resistance

(2012) Mark A Wainberg et al.   Current Opinion in Virology

Cell-to-cell transmission of viruses

(2012) Peng Zhong et al.   Current Opinion in Virology

HIV Drug Resistance and the Advent of Integrase Inhibitors

(2012) Peter K. Quashie et al.   Current Infectious Disease Reports

Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

(2011) P. K. Quashie et al.   JOURNAL OF VIROLOGY

Multiploid Inheritance of HIV-1 during Cell-to-Cell Infection

(2011) A. Del Portillo et al.   JOURNAL OF VIROLOGY

Compensation by the E138K Mutation in HIV-1 Reverse Transcriptase for Deficits in Viral Replication Capacity and Enzyme Processivity Associated with the M184I/V Mutations

(2011) H.-T. Xu et al.   JOURNAL OF VIROLOGY

Interaction of Reverse Transcriptase (RT) Mutations Conferring Resistance to Lamivudine and Etravirine: Effects on Fitness and RT Activity of Human Immunodeficiency Virus Type 1

(2011) Z. Hu et al.   JOURNAL OF VIROLOGY

Tetherin restricts direct cell-to-cell infection of HIV-1

(2011) Björn D Kuhl et al.   Retrovirology

Resistance to HIV-1 integrase inhibitors: A structural perspective

(2010) Jean-François Mouscadet et al.   DRUG RESISTANCE UPDATES

Simultaneous Cell-to-Cell Transmission of Human Immunodeficiency Virus to Multiple Targets through Polysynapses

(2009) D. Rudnicka et al.   JOURNAL OF VIROLOGY

The Challenge of Finding a Cure for HIV Infection

(2009) D. D. Richman et al.   SCIENCE

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY

HIV rebounds from latently infected cells, rather than from continuing low-level replication

(2008) B. Joos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA