KSHV miRNAs Decrease Expression of Lytic Genes in Latently Infected PEL and Endothelial Cells by Targeting Host Transcription Factors

A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells

(2014) Yajie Yang et al.   BMC GENOMICS

Kaposi's Sarcoma-Associated Herpesvirus K3 and K5 Ubiquitin E3 Ligases Have Stage-Specific Immune Evasion Roles during Lytic Replication

(2014) K. Brulois et al.   JOURNAL OF VIROLOGY

Helminth infection reactivates latent  -herpesvirus via cytokine competition at a viral promoter

(2014) T. A. Reese et al.   SCIENCE

Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Single-Nucleotide Polymorphisms Identified in Clinical Samples Can Affect MicroRNA Processing, Level of Expression, and Silencing Activity

(2013) S.-J. Han et al.   JOURNAL OF VIROLOGY

γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis

(2013) Ying Zhu et al.   Current Opinion in Virology

KSHV MicroRNAs Mediate Cellular Transformation and Tumorigenesis by Redundantly Targeting Cell Growth and Survival Pathways

(2013) Rosalie Moody et al.   PLoS Pathogens

Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line

(2012) Michael Stürzl et al.   INTERNATIONAL JOURNAL OF CANCER

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

(2012) Kevin F. Brulois et al.   JOURNAL OF VIROLOGY

Ago HITS-CLIP Expands Understanding of Kaposi's Sarcoma-associated Herpesvirus miRNA Function in Primary Effusion Lymphomas

(2012) Irina Haecker et al.   PLoS Pathogens

A core laboratory for the generation of quality-controlled g-herpesvirus bacmids: generation of KSHV microRNA mutants

(2012) Brian Krueger et al.   Infectious Agents and Cancer

Viral MicroRNA Targetome of KSHV-Infected Primary Effusion Lymphoma Cell Lines

(2011) Eva Gottwein et al.   Cell Host & Microbe

Kinetic Analysis Reveals the Fate of a MicroRNA following Target Regulation in Mammalian Cells

(2011) Alessia Baccarini et al.   CURRENT BIOLOGY

Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction

(2011) Jinjong Myoung et al.   JOURNAL OF VIROLOGICAL METHODS

A Kaposi's Sarcoma-Associated Herpesvirus-Encoded Ortholog of MicroRNA miR-155 Induces Human Splenic B-Cell Expansion in NOD/LtSz-scid IL2R null Mice

(2011) I. W. Boss et al.   JOURNAL OF VIROLOGY

Infection of Lymphoblastoid Cell Lines by Kaposi's Sarcoma-Associated Herpesvirus: Critical Role of Cell-Associated Virus

(2011) J. Myoung et al.   JOURNAL OF VIROLOGY

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTA

(2011) Xianzhi Lin et al.   PLoS One

Viruses, microRNAs, and Host Interactions

(2010) Rebecca L. Skalsky et al.   Annual Review of Microbiology

Viral Latency and Its Regulation: Lessons from the γ-Herpesviruses

(2010) Samuel H. Speck et al.   Cell Host & Microbe

Array-Based Transcript Profiling and Limiting-Dilution Reverse Transcription-PCR Analysis Identify Additional Latent Genes in Kaposi's Sarcoma-Associated Herpesvirus

(2010) S. Chandriani et al.   JOURNAL OF VIROLOGY

Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency by Virus-Encoded MicroRNAs That Target Rta and the Cellular Rbl2-DNMT Pathway

(2010) F. Lu et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus ORF57 Interacts with Cellular RNA Export Cofactors RBM15 and OTT3 To Promote Expression of Viral ORF59

(2010) V. Majerciak et al.   JOURNAL OF VIROLOGY

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA

(2010) Xiufen Lei et al.   NATURE CELL BIOLOGY

Regulation of KSHV Lytic Switch Protein Expression by a Virus-Encoded MicroRNA: An Evolutionary Adaptation that Fine-Tunes Lytic Reactivation

(2009) Priya Bellare et al.   Cell Host & Microbe

Wide-Scale Use of Notch Signaling Factor CSL/RBP-J  in RTA-Mediated Activation of Kaposi's Sarcoma-Associated Herpesvirus Lytic Genes

(2009) L. M. Persson et al.   JOURNAL OF VIROLOGY

Pre-Micro RNA Signatures Delineate Stages of Endothelial Cell Transformation in Kaposi Sarcoma

(2009) Andrea J. O'Hara et al.   PLoS Pathogens

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Dysregulation of the C/EBPα Differentiation Pathway in Human Cancer

(2008) Steffen Koschmieder et al.   JOURNAL OF CLINICAL ONCOLOGY

Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs

(2008) Joseph M Ziegelbauer et al.   NATURE GENETICS

Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: Implications for latency

(2008) E. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA