CD81-Receptor Associations — Impact for Hepatitis C Virus Entry and Antiviral Therapies

HRas Signal Transduction Promotes Hepatitis C Virus Cell Entry by Triggering Assembly of the Host Tetraspanin Receptor Complex

(2013) Laetitia Zona et al.   Cell Host & Microbe

Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha

(2013) Joachim Lupberger et al.   HEPATOLOGY

Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry

(2013) Florian Douam et al.   HEPATOLOGY

Discovery of Cellular Proteins Required for the Early Steps of HCV Infection Using Integrative Genomics

(2013) Ji Hoon Park et al.   PLoS One

A Novel Monoclonal Anti-CD81 Antibody Produced by Genetic Immunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission

(2013) Isabel Fofana et al.   PLoS One

In silicodirected mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface

(2012) Christopher Davis et al.   CELLULAR MICROBIOLOGY

Hepatoma polarization limits CD81 and hepatitis C virus dynamics

(2012) H. J. Harris et al.   CELLULAR MICROBIOLOGY

Mutations That Alter Use of Hepatitis C Virus Cell Entry Factors Mediate Escape From Neutralizing Antibodies

(2012) Isabel Fofana et al.   GASTROENTEROLOGY

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

A human claudin-1-derived peptide inhibits hepatitis C virus entry

(2012) Youhui Si et al.   HEPATOLOGY

Transient Activation of the PI3K-AKT Pathway by Hepatitis C Virus to Enhance Viral Entry

(2012) Zhe Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host-targeting agents for prevention and treatment of chronic hepatitis C – Perspectives and challenges

(2012) Mirjam B. Zeisel et al.   JOURNAL OF HEPATOLOGY

Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis

(2012) Michelle J. Farquhar et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Induces Epidermal Growth Factor Receptor Activation via CD81 Binding for Viral Internalization and Entry

(2012) J. Diao et al.   JOURNAL OF VIROLOGY

Interacting Regions of CD81 and Two of Its Partners, EWI-2 and EWI-2wint, and Their Effect on Hepatitis C Virus Infection

(2011) Claire Montpellier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

(2011) Joachim Lupberger et al.   NATURE MEDICINE

Efficient production of antibodies against a mammalian integral membrane protein by phage display

(2011) Isidro Hötzel et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Integrin Inhibitors as a Therapeutic Agent for Ovarian Cancer

(2011) Kenjiro Sawada et al.   Journal of Oncology

Monoclonal Anti-Claudin 1 Antibodies Prevent Hepatitis C Virus Infection of Primary Human Hepatocytes

(2010) Isabel Fofana et al.   GASTROENTEROLOGY

Kinase inhibitors in the treatment of chronic hepatitis C virus

(2010) E. Bardou-Jacquet et al.   GUT

Claudin Association with CD81 Defines Hepatitis C Virus Entry

(2010) Helen J. Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

(2010) Menno C. van Zelm et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel Function of CD81 in Controlling Hepatitis C Virus Replication

(2010) Y.-Y. Zhang et al.   JOURNAL OF VIROLOGY

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

(2010) C. L. Brimacombe et al.   JOURNAL OF VIROLOGY

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

The hepatitis C virus and its hepatic environment: a toxic but finely tuned partnership

(2009) Marie Perrault et al.   BIOCHEMICAL JOURNAL

Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles

(2009) Wagane J. A. Benga et al.   HEPATOLOGY

Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-Claudin-1 associations

(2009) Sophie E. Krieger et al.   HEPATOLOGY

Tetraspanin CD81 Is Required for Listeria monocytogenes Invasion

(2009) T. N. Tham et al.   INFECTION AND IMMUNITY

Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization

(2009) A. K. Schwarz et al.   JOURNAL OF VIROLOGY

Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

(2009) C. J. Mee et al.   JOURNAL OF VIROLOGY

Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo

(2008) Philip Meuleman et al.   HEPATOLOGY

Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly

(2008) Vlastimil Jirasko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation of the Tight Junction-like Distribution of Claudin-1 to the Cellular Tropism of Hepatitis C Virus

(2008) Wei Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry

(2008) H. J. Harris et al.   JOURNAL OF VIROLOGY

The Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious Virus

(2008) D. M. Jones et al.   JOURNAL OF VIROLOGY

NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

(2008) Y. Ma et al.   JOURNAL OF VIROLOGY

Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity

(2008) M. J. Farquhar et al.   JOURNAL OF VIROLOGY

CD81 Is a Central Regulator of Cellular Events Required for Hepatitis C Virus Infection of Human Hepatocytes

(2008) M. Brazzoli et al.   JOURNAL OF VIROLOGY

Hepatocyte Permissiveness to Plasmodium Infection Is Conveyed by a Short and Structurally Conserved Region of the CD81 Large Extracellular Domain

(2008) Samir Yalaoui et al.   PLoS Pathogens

Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry

(2007) Cécile Voisset et al.   CELLULAR MICROBIOLOGY