Mechanism of West Nile Virus Neuroinvasion: A Critical Appraisal

Drak2 Contributes to West Nile Virus Entry into the Brain and Lethal Encephalitis

(2014) S. Wang et al.   JOURNAL OF IMMUNOLOGY

Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

(2014) Mukesh Kumar et al.   Journal of Neuroinflammation

Experimental Infection of Rhesus Macaques and Common Marmosets with a European Strain of West Nile Virus

(2014) Babs E. Verstrepen et al.   PLoS Neglected Tropical Diseases

Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain

(2013) Fanny Langlet et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Novel Recombinant Hepatitis B Virus Vectors Efficiently Deliver Protein and RNA Encoding Genes into Primary Hepatocytes

(2013) R. Hong et al.   JOURNAL OF VIROLOGY

Death Receptor-Mediated Apoptotic Signaling Is Activated in the Brain following Infection with West Nile Virus in the Absence of a Peripheral Immune Response

(2013) P. Clarke et al.   JOURNAL OF VIROLOGY

West Nile virus infection and immunity

(2013) Mehul S. Suthar et al.   NATURE REVIEWS MICROBIOLOGY

West Nile virus introduction into the new world

(2013) I. Steiner et al.   NEUROLOGY

West Nile Virus Prevalence across Landscapes Is Mediated by Local Effects of Agriculture on Vector and Host Communities

(2013) David W. Crowder et al.   PLoS One

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenicity of Japanese Encephalitis Virus Envelope Protein by Hyphantria cunea Nuclear Polyhedrosis Virus Vector in Guinea Pig

(2012) Hyung-Hoan Lee et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

The contribution of rodent models to the pathological assessment of flaviviral infections of the central nervous system

(2012) David C. Clark et al.   ARCHIVES OF VIROLOGY

Neuro-invasion by a ‘Trojan Horse’ strategy and vasculopathy during intrauterine flavivirus infection

(2012) Helle Bielefeldt-Ohmann et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Blood–Spinal Cord Barrier Pericyte Reductions Contribute to Increased Capillary Permeability

(2012) Ethan A Winkler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Molecular evolution of lineage 2 West Nile virus

(2012) A. R. McMullen et al.   JOURNAL OF GENERAL VIROLOGY

West Nile virus-induced disruption of the blood-brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

(2012) K. Roe et al.   JOURNAL OF GENERAL VIROLOGY

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

(2012) Daniel R Getts et al.   Journal of Neuroinflammation

Respiratory Insufficiency Correlated Strongly with Mortality of Rodents Infected with West Nile Virus

(2012) John D. Morrey et al.   PLoS One

West Nile Virus Infection Causes Endocytosis of a Specific Subset of Tight Junction Membrane Proteins

(2012) Zaikun Xu et al.   PLoS One

Mutational analysis of the West Nile virus NS4B protein

(2012) Jason A. Wicker et al.   VIROLOGY

Barrier Mechanisms in the Developing Brain

(2012) Norman R. Saunders et al.   Frontiers in Pharmacology

The blood-spinal cord barrier: Morphology and Clinical Implications

(2011) Viktor Bartanusz et al.   ANNALS OF NEUROLOGY

Blood–arachnoid barrier disruption in experimental rat meningitis detected using gadolinium-enhancement ratio imaging

(2011) Hiroyuki Ichikawa et al.   BRAIN RESEARCH

Envelope and pre-membrane protein structural amino acid mutations mediate diminished avian growth and virulence of a Mexican West Nile virus isolate

(2011) S. A. Langevin et al.   JOURNAL OF GENERAL VIROLOGY

Autophagy is involved in the early step of Japanese encephalitis virus infection

(2011) Jin-Kun Li et al.   MICROBES AND INFECTION

Autonomic Nervous Dysfunction in Hamsters Infected with West Nile Virus

(2011) Hong Wang et al.   PLoS One

Neuroinvasive flavivirus infections

(2011) Gregorius J. Sips et al.   REVIEWS IN MEDICAL VIROLOGY

Immune responses to an attenuated West Nile virus NS4B-P38G mutant strain

(2011) Thomas Welte et al.   VACCINE

Multiple amino acid changes at the first glycosylation motif in NS1 protein of West Nile virus are necessary for complete attenuation for mouse neuroinvasiveness

(2011) Melissa C. Whiteman et al.   VACCINE

Virulence determinants between New York 99 and Kunjin strains of West Nile virus

(2011) Michelle Audsley et al.   VIROLOGY

The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication

(2011) Jean-Baptiste Brault et al.   VIROLOGY

West Nile Virus: Immunity and Pathogenesis

(2011) Stephanie M. Lim et al.   Viruses-Basel

West Nile Virus Neuroinvasive Disease

(2011) Roberta L. DeBiasi   Current Infectious Disease Reports

Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein

(2010) Rie Hasebe et al.   BMC MICROBIOLOGY

Pro-inflammatory cytokines derived from West Nile virus (WNV)-infected SK-N-SH cells mediate neuroinflammatory markers and neuronal death

(2010) Mukesh Kumar et al.   Journal of Neuroinflammation

The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

(2010) M. Laurent-Rolle et al.   JOURNAL OF VIROLOGY

Phylogeography of West Nile Virus: from the Cradle of Evolution in Africa to Eurasia, Australia, and the Americas

(2010) F. J. May et al.   JOURNAL OF VIROLOGY

Persistence of West Nile Virus in the Central Nervous System and Periphery of Mice

(2010) Kim K. Appler et al.   PLoS One

Simulation of the seasonal cycles of bird, equine and human West Nile virus cases

(2010) Vincent Laperriere et al.   PREVENTIVE VETERINARY MEDICINE

Viral pathogenesis in mice is similar for West Nile virus derived from mosquito and mammalian cells

(2010) Pei-Yin Lim et al.   VIROLOGY

Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2′,5′-oligoadenylate synthetase 1b

(2010) Eva Mertens et al.   VIROLOGY

The host immunologic response to West Nile encephalitis virus

(2009) Michael et al.   Frontiers in Bioscience-Landmark

Brain Lesions Induced by Experimental Intranasal Infection of Japanese Encephalitis Virus in Piglets

(2009) M. Yamada et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Nocodazole delays viral entry into the brain following footpad inoculation with West Nile virus in mice

(2009) EA Hunsperger et al.   JOURNAL OF NEUROVIROLOGY

West Nile virus preferentially transports along motor neuron axons after sciatic nerve injection of hamsters

(2009) Hong Wang et al.   JOURNAL OF NEUROVIROLOGY

NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness

(2009) E. B. Melian et al.   JOURNAL OF VIROLOGY

West Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier Function

(2009) G. R. Medigeshi et al.   JOURNAL OF VIROLOGY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Cellular Elements of the Blood-Brain Barrier

(2009) Jorge Correale et al.   NEUROCHEMICAL RESEARCH

Development and characterization of non-glycosylated E and NS1 mutant viruses as a potential candidate vaccine for West Nile virus

(2009) Melissa C. Whiteman et al.   VACCINE

Changing patterns of West Nile virus transmission: altered vector competence and host susceptibility

(2009) Aaron C. Brault   VETERINARY RESEARCH

West Nile virus infection modulates human brain microvascular endothelial cells tight junction proteins and cell adhesion molecules: Transmigration across the in vitro blood-brain barrier

(2009) Saguna Verma et al.   VIROLOGY

Reversal of West Nile virus-induced blood–brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor

(2009) Saguna Verma et al.   VIROLOGY

Increased blood brain barrier permeability is not a primary determinant for lethality of West Nile virus infection in rodents

(2008) J. D. Morrey et al.   JOURNAL OF GENERAL VIROLOGY

ICAM-1 Participates in the Entry of West Nile Virus into the Central Nervous System

(2008) J. Dai et al.   JOURNAL OF VIROLOGY

Tumor Necrosis Factor Alpha Protects against Lethal West Nile Virus Infection by Promoting Trafficking of Mononuclear Leukocytes into the Central Nervous System

(2008) B. Shrestha et al.   JOURNAL OF VIROLOGY

Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly

(2008) K.-F. Kong et al.   JOURNAL OF VIROLOGY

Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking

(2008) Hekla Sigmundsdottir et al.   NATURE IMMUNOLOGY

Barriers in the brain: a renaissance?

(2008) Norman R. Saunders et al.   TRENDS IN NEUROSCIENCES

A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor

(2008) Gang Zou et al.   VIROLOGY