Viral Subversion of the Nuclear Pore Complex

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2

(2013) Daniel H. Lin et al.   JOURNAL OF MOLECULAR BIOLOGY

Importin α3/Qip1 Is Involved in Multiplication of Mutant Influenza Virus with Alanine Mutation at Amino Acid 9 Independently of Nuclear Transport Function

(2013) Yutaka Sasaki et al.   PLoS One

LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus

(2013) D. Finkelshtein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6

(2013) Thomas Fricke et al.   Retrovirology

High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71

(2013) Jeffrey D. Levengood et al.   RNA Biology

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

(2013) Francesca Di Nunzio et al.   VIROLOGY

Uncoating of non-enveloped viruses

(2013) Maarit Suomalainen et al.   Current Opinion in Virology

The molecular basis of HIV entry

(2012) Per Johan Klasse   CELLULAR MICROBIOLOGY

Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity

(2012) Olivier Béaslas et al.   EXPERIMENTAL CELL RESEARCH

Recent advances in understanding viral evasion of type I interferon

(2012) Kathryne E. Taylor et al.   IMMUNOLOGY

Contribution of Host Nucleoporin 62 in HIV-1 Integrase Chromatin Association and Viral DNA Integration

(2012) Zhujun Ao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Herpes Simplex Virus ICP27 Protein Directly Interacts with the Nuclear Pore Complex through Nup62, Inhibiting Host Nucleocytoplasmic Transport Pathways

(2012) Poonam Malik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epstein-Barr Virus Protein Kinase BGLF4 Targets the Nucleus through Interaction with Nucleoporins

(2012) C.-W. Chang et al.   JOURNAL OF VIROLOGY

Entry of Hepatitis B Virus into Immortalized Human Primary Hepatocytes by Clathrin-Dependent Endocytosis

(2012) H.-C. Huang et al.   JOURNAL OF VIROLOGY

A Nuclear Localization Signal in Herpesvirus Protein VP1-2 Is Essential for Infection via Capsid Routing to the Nuclear Pore

(2012) F. Abaitua et al.   JOURNAL OF VIROLOGY

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: Protein synthesis, cell proliferation, and T-cell activation

(2012) Arti T. Navare et al.   VIROLOGY

Complexes of Vesicular Stomatitis Virus Matrix Protein with Host Rae1 and Nup98 Involved in Inhibition of Host Transcription

(2012) Karishma R. Rajani et al.   PLoS Pathogens

Characterization of Staufen1 Ribonucleoproteins by Mass Spectrometry and Biochemical Analyses Reveal the Presence of Diverse Host Proteins Associated with Human Immunodeficiency Virus Type 1

(2012) Miroslav P. Milev et al.   Frontiers in Microbiology

Virus strategies for passing the nuclear envelope barrier

(2012) Oren Kobiler et al.   Nucleus

The Structure of the Nuclear Pore Complex

(2011) André Hoelz et al.   Annual Review of Biochemistry

Kinesin-1-Mediated Capsid Disassembly and Disruption of the Nuclear Pore Complex Promote Virus Infection

(2011) Sten Strunze et al.   Cell Host & Microbe

Examining the requirements for nucleoporins by HIV-1

(2011) Anne Monette et al.   Future Microbiology

The Multifaceted Poliovirus 2A Protease: Regulation of Gene Expression by Picornavirus Proteases

(2011) Alfredo Castelló et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

HIV-1 remodels the nuclear pore complex

(2011) Anne Monette et al.   JOURNAL OF CELL BIOLOGY

Identification of Critical Motifs within HIV-1 Integrase Required for Importin α3 Interaction and Viral cDNA Nuclear Import

(2011) Kallesh Danappa Jayappa et al.   JOURNAL OF MOLECULAR BIOLOGY

Nuclear delivery mechanism of herpes simplex virus type 1 genome

(2011) Ivan Liashkovich et al.   JOURNAL OF MOLECULAR RECOGNITION

The Requirement for Nucleoporin NUP153 during Human Immunodeficiency Virus Type 1 Infection Is Determined by the Viral Capsid

(2011) K. A. Matreyek et al.   JOURNAL OF VIROLOGY

CRM1-Dependent Transport Supports Cytoplasmic Accumulation of Adenoviral Early Transcripts

(2011) M. Schmid et al.   JOURNAL OF VIROLOGY

Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression

(2011) Nicole Lund et al.   NUCLEIC ACIDS RESEARCH

Adenovirus Recruits Dynein by an Evolutionary Novel Mechanism Involving Direct Binding to pH-Primed Hexon

(2011) Julian Scherer et al.   Viruses-Basel

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

(2011) Karen E. Ocwieja et al.   PLoS Pathogens

Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting

(2011) Geoffrey P. Chase et al.   PLoS Pathogens

How viruses access the nucleus

(2010) Sarah Cohen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Cellular Networks Involved in the Influenza Virus Life Cycle

(2010) Tokiko Watanabe et al.   Cell Host & Microbe

Human cellular protein nucleoporin hNup98 interacts with influenza A virus NS2/nuclear export protein and overexpression of its GLFG repeat domain can inhibit virus propagation

(2010) J. Chen et al.   JOURNAL OF GENERAL VIROLOGY

Export of Adenoviral Late mRNA from the Nucleus Requires the Nxf1/Tap Export Receptor

(2010) G. Yatherajam et al.   JOURNAL OF VIROLOGY

Stepwise Loss of Fluorescent Core Protein V from Human Adenovirus during Entry into Cells

(2010) D. Puntener et al.   JOURNAL OF VIROLOGY

Nucleoporin Phosphorylation Triggered by the Encephalomyocarditis Virus Leader Protein Is Mediated by Mitogen-Activated Protein Kinases

(2010) F. W. Porter et al.   JOURNAL OF VIROLOGY

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

The nuclear pore complex: bridging nuclear transport and gene regulation

(2010) Caterina Strambio-De-Castillia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Perturbation of Host Nuclear Membrane Component RanBP2 Impairs the Nuclear Import of Human Immunodeficiency Virus -1 Preintegration Complex (DNA)

(2010) Ruonan Zhang et al.   PLoS One

Escape of herpesviruses from the nucleus

(2010) Chung-Pei Lee et al.   REVIEWS IN MEDICAL VIROLOGY

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket

(2010) André Schmitz et al.   PLoS Pathogens

Plus- and Minus-End Directed Microtubule Motors Bind Simultaneously to Herpes Simplex Virus Capsids Using Different Inner Tegument Structures

(2010) Kerstin Radtke et al.   PLoS Pathogens

Characterisation of the passive permeability barrier of nuclear pore complexes

(2009) Dagmar Mohr et al.   EMBO JOURNAL

Human Immunodeficiency Virus Type 1 (HIV-1) Induces the Cytoplasmic Retention of Heterogeneous Nuclear Ribonucleoprotein A1 by Disrupting Nuclear Import

(2009) Anne Monette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cellular RNA Export Receptor TAP/NXF1 Is Required for ICP27-Mediated Export of Herpes Simplex Virus 1 RNA, but the TREX Complex Adaptor Protein Aly/REF Appears To Be Dispensable

(2009) L. A. Johnson et al.   JOURNAL OF VIROLOGY

Dynamic Host Energetics and Cytoskeletal Proteomes in Human Immunodeficiency Virus Type 1-Infected Human Primary CD4 Cells: Analysis by Multiplexed Label-Free Mass Spectrometry

(2009) E. Y. Chan et al.   JOURNAL OF VIROLOGY

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1

(2009) C. L. Woodward et al.   JOURNAL OF VIROLOGY

hnRNP A1 Interacts with the 5' Untranslated Regions of Enterovirus 71 and Sindbis Virus RNA and Is Required for Viral Replication

(2009) J.-Y. Lin et al.   JOURNAL OF VIROLOGY

Mengovirus-Induced Rearrangement of the Nuclear Pore Complex: Hijacking Cellular Phosphorylation Machinery

(2009) M. V. Bardina et al.   JOURNAL OF VIROLOGY

Herpesvirus Capsid Association with the Nuclear Pore Complex and Viral DNA Release Involve the Nucleoporin CAN/Nup214 and the Capsid Protein pUL25

(2009) D. Pasdeloup et al.   JOURNAL OF VIROLOGY

Human host factors required for influenza virus replication

(2009) Renate König et al.   NATURE

Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells

(2009) Michaël Imbeault et al.   Retrovirology

Nuclear Entry of Hepatitis B Virus Capsids Involves Disintegration to Protein Dimers followed by Nuclear Reassociation to Capsids

(2009) Birgit Rabe et al.   PLoS Pathogens

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

Entry of herpesviruses into mammalian cells

(2008) E. E. Heldwein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of mRNA export and dimerization of interferon regulatory factor 3 by Theiler's virus leader protein

(2008) C. Ricour et al.   JOURNAL OF GENERAL VIROLOGY

The UL25 Gene Product of Herpes Simplex Virus Type 1 Is Involved in Uncoating of the Viral Genome

(2008) V. G. Preston et al.   JOURNAL OF VIROLOGY

Leader-Induced Phosphorylation of Nucleoporins Correlates with Nuclear Trafficking Inhibition by Cardioviruses

(2008) F. W. Porter et al.   JOURNAL OF VIROLOGY

Proteolytic Cleavage of VP1-2 Is Required for Release of Herpes Simplex Virus 1 DNA into the Nucleus

(2008) V. Jovasevic et al.   JOURNAL OF VIROLOGY

Exploring the Nuclear Envelope of Herpes Simplex Virus 1-Infected Cells by High-Resolution Microscopy

(2008) P. Wild et al.   JOURNAL OF VIROLOGY

hnRNPs Relocalize to the Cytoplasm following Infection with Vesicular Stomatitis Virus

(2008) E. L. Pettit Kneller et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment

(2008) A. M. Copeland et al.   JOURNAL OF VIROLOGY

Drosophila RNAi screen identifies host genes important for influenza virus replication

(2008) Linhui Hao et al.   NATURE

Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus

(2008) Gülsah Gabriel et al.   PLoS Pathogens

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE