Make Yourself at Home: Viral Hijacking of the PI3K/Akt Signaling Pathway

Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling

(2014) S. Kaur et al.   JOURNAL OF IMMUNOLOGY

Quantitative Phosphoproteomics Reveals Extensive Cellular Reprogramming during HIV-1 Entry

(2013) Jason A. Wojcechowskyj et al.   Cell Host & Microbe

Pick one, but be quick: 5' splice sites and the problems of too many choices

(2013) X. Roca et al.   GENES & DEVELOPMENT

hnRNP U Enhances Caspase-9 Splicing and Is Modulated by AKT-dependent Phosphorylation of hnRNP L

(2013) Ngoc T. Vu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accumulation of Splice Variants and Transcripts in Response to PI3K Inhibition in T Cells

(2013) Alice Riedel et al.   PLoS One

The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia

(2012) L. Zuurbier et al.   HAEMATOLOGICA

Transient Activation of the PI3K-AKT Pathway by Hepatitis C Virus to Enhance Viral Entry

(2012) Zhe Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin  1 Mediates Vaccinia Virus Entry through Activation of PI3K/Akt Signaling

(2012) R. Izmailyan et al.   JOURNAL OF VIROLOGY

Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

(2012) Z. Surviladze et al.   JOURNAL OF VIROLOGY

Strain-Specific Contribution of NS1-Activated Phosphoinositide 3-Kinase Signaling to Influenza A Virus Replication and Virulence

(2012) J. Ayllon et al.   JOURNAL OF VIROLOGY

The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus

(2012) Zhihong Zhou et al.   MOLECULAR CELL

Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms

(2012) S. Erkelenz et al.   RNA

Influenza A viruses and PI3K

(2012) Juan Ayllon et al.   Virulence

African Swine Fever Virus Uses Macropinocytosis to Enter Host Cells

(2012) Elena G. Sánchez et al.   PLoS Pathogens

The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses

(2011) S.-z. Feng et al.   JOURNAL OF GENERAL VIROLOGY

The Ras–PI3K Signaling Pathway Is Involved in Clathrin-Independent Endocytosis and the Internalization of Influenza Viruses

(2011) Yoichiro Fujioka et al.   PLoS One

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

(2011) Mohammad F. Saeed et al.   PLoS Pathogens

Virus Entry by Endocytosis

(2010) Jason Mercer et al.   Annual Review of Biochemistry

Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a

(2010) J. C. Shultz et al.   CANCER RESEARCH

Akt and mRNA translation by interferons

(2010) Surinder Kaur et al.   CELL CYCLE

Influenza A virus-induced early activation of ERK and PI3K mediates V-ATPase-dependent intracellular pH change required for fusion

(2010) Henju Marjuki et al.   CELLULAR MICROBIOLOGY

Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry

(2010) V. Tiwari et al.   JOURNAL OF GENERAL VIROLOGY

Rotavirus Nonstructural Protein 1 Suppresses Virus-Induced Cellular Apoptosis To Facilitate Viral Growth by Activating the Cell Survival Pathways during Early Stages of Infection

(2010) P. Bagchi et al.   JOURNAL OF VIROLOGY

The Human Papillomavirus Type 16 E6 Oncoprotein Activates mTORC1 Signaling and Increases Protein Synthesis

(2010) J. M. Spangle et al.   JOURNAL OF VIROLOGY

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of viral entry: sneaking in the front door

(2010) Jennifer A. Thorley et al.   PROTOPLASMA

Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold

(2010) K. K. Singh et al.   RNA

Activation of PI 3-kinase/Akt/NF-κB and Stat3 signaling by avian reovirus S1133 in the early stages of infection results in an inflammatory response and delayed apoptosis

(2010) Ping-Yuan Lin et al.   VIROLOGY

The Role of Lipids in Retrovirus Replication

(2010) Abdul A. Waheed et al.   Viruses-Basel

The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells

(2010) Thorsten Eierhoff et al.   PLoS Pathogens

A role for heparan sulfate in viral surfing

(2009) Myung-Jin Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interaction of Akt-phosphorylated SRPK2 with 14-3-3 Mediates Cell Cycle and Cell Death in Neurons

(2009) Sung-Wuk Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency

(2009) L. Peng et al.   JOURNAL OF GENERAL VIROLOGY

Phosphatidylinositol 3-Kinase Regulates Macrophage Responses to Double-Stranded RNA and Encephalomyocarditis Virus

(2009) Wieke Freudenburg et al.   Journal of Innate Immunity

PI3K Signaling Regulates Rapamycin-Insensitive Translation Initiation Complex Formation in Vaccinia Virus-Infected Cells

(2009) I. Zaborowska et al.   JOURNAL OF VIROLOGY

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

(2009) J. A. P. Soares et al.   JOURNAL OF VIROLOGY

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K)

(2009) David Jackson et al.   VIROLOGY

The life of a cell: apoptosis regulation by the PI3K/PKB pathway

(2008) Vincent Duronio   BIOCHEMICAL JOURNAL

Akt2 Regulation of Cdc2-Like Kinases (Clk/Sty), Serine/Arginine-Rich (SR) Protein Phosphorylation, and Insulin-Induced Alternative Splicing of PKCβII Messenger Ribonucleic Acid

(2008) Kun Jiang et al.   ENDOCRINOLOGY

In VivoAnalysis of Protein Kinase B (PKB)/Akt Regulation in DNA-PKcs-null Mice Reveals a Role for PKB/Akt in DNA Damage Response and Tumorigenesis

(2008) Banu Surucu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

PKBα/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival

(2008) Lana Bozulic et al.   MOLECULAR CELL

Role of the Akt pathway in mRNA translation of interferon-stimulated genes

(2008) S. Kaur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages

(2008) Dinushka Dowling et al.   Retrovirology

Viral Control of Mitochondrial Apoptosis

(2008) Lorenzo Galluzzi et al.   PLoS Pathogens

Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells In Vitro

(2007) Elisabetta Calzavara et al.   JOURNAL OF CELLULAR BIOCHEMISTRY