Journal
VIRUSES-BASEL
Volume 5, Issue 11, Pages 2690-2703Publisher
MDPI
DOI: 10.3390/v5112690
Keywords
hepatitis B virus; microRNA; hepatocellular carcinoma
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Funding
- Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation of Japan
- Project for Development of Innovative Research on Cancer Therapeutics (P-Direct)
- Scientific Research on Priority Areas Cancer from the Japanese Ministry of Education, Culture, Sports, Science, and Technology
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The hepatitis B virus (HBV) is a small enveloped DNA virus that belongs to the Hepadnaviridae family. HBV can cause acute and persistent infection which can lead to hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play a crucial role in the main cellular events. The dysregulation of their expression has been linked to the development of the cancer as well as to viral interference. This chapter will describe the involvement of miRNAs in the case of HBV infection and their implication in the development of the HBV-related diseases.
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