Cellular Prion Protein: From Physiology to Pathology

Cellular Prion Protein Regulates Its Own α-Cleavage through ADAM8 in Skeletal Muscle

(2012) Jingjing Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrPC-deficiency

(2012) N. Daude et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PK-sensitive PrPSc Is Infectious and Shares Basic Structural Features with PK-resistant PrPSc

(2012) Gustavo Sajnani et al.   PLoS Pathogens

A Naturally Occurring C-terminal Fragment of the Prion Protein (PrP) Delays Disease and Acts as a Dominant-negative Inhibitor of PrPScFormation

(2011) Laura Westergard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nine Amino Acid Domain Is Essential for Mutant Prion Protein Toxicity

(2011) L. Westergard et al.   JOURNAL OF NEUROSCIENCE

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

(2011) Hermann C Altmeppen et al.   Molecular Neurodegeneration

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

(2011) Malin K. Sandberg et al.   NATURE

A Simple, Versatile and Sensitive Cell-Based Assay for Prions from Various Species

(2011) Zaira E. Arellano-Anaya et al.   PLoS One

Prion protein function and the disturbance of early embryonic development in zebrafish

(2011) Mohasina Syed et al.   Prion

Spontaneous generation of anchorless prions in transgenic mice

(2011) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

Rapid cell-surface prion protein conversion revealed using a novel cell system

(2011) R. Goold et al.   Nature Communications

Biochemical Signatures of Doppel Protein in Human Astrocytomas to Support Prediction in Tumor Malignancy

(2010) Paola Rognoni et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Possible involvement of calpain-like activity in normal processing of cellular prion protein

(2010) Naomi Hachiya et al.   NEUROSCIENCE LETTERS

Unexpected Tolerance of α-Cleavage of the Prion Protein to Sequence Variations

(2010) José B. Oliveira-Martins et al.   PLoS One

Interactions of Prion Protein With Intracellular Proteins: So Many Partners and no Consequences?

(2009) Krzysztof Nieznanski   CELLULAR AND MOLECULAR NEUROBIOLOGY

Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein

(2009) Brent Race et al.   EXPERIMENTAL NEUROLOGY

The prion or the related Shadoo protein is required for early mouse embryogenesis

(2009) Rachel Young et al.   FEBS LETTERS

Role of ADAMs in the Ectodomain Shedding and Conformational Conversion of the Prion Protein

(2009) David R. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP

(2009) W. Yang et al.   JOURNAL OF NEUROSCIENCE

Spontaneous Generation of Prion Infectivity in Fatal Familial Insomnia Knockin Mice

(2009) Walker S. Jackson et al.   NEURON

Functionally Relevant Domains of the Prion Protein Identified In Vivo

(2009) Frank Baumann et al.   PLoS One

Hypoxia induces expression of a GPI-anchorless splice variant of the prion protein

(2008) Yutaka Kikuchi et al.   FEBS Journal

Mutant Prion Protein Expression Causes Motor and Memory Deficits and Abnormal Sleep Patterns in a Transgenic Mouse Model

(2008) Sara Dossena et al.   NEURON

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS

Scrapie-Infected Mice and PrP Knockout Mice Share Abnormal Localization and Activity of Neuronal Nitric Oxide Synthase

(2003) Gilmor I. Keshet et al.   JOURNAL OF NEUROCHEMISTRY