Modulation of Apoptotic Pathways by Human Papillomaviruses (HPV): Mechanisms and Implications for Therapy

Small molecule inhibitors of the HPV16-E6 interaction with caspase 8

(2012) Chung-Hsiang Yuan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cervical Cancers Require the Continuous Expression of the Human Papillomavirus Type 16 E7 Oncoprotein Even in the Presence of the Viral E6 Oncoprotein

(2012) Sean F. Jabbar et al.   CANCER RESEARCH

Genital human papillomavirus infections: current and prospective therapies

(2012) M. A. Stanley   JOURNAL OF GENERAL VIROLOGY

Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplantation

(2012) YeWei Zhang et al.   Science China-Life Sciences

Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21WAF1/CIP1

(2011) D Sohn et al.   CELL DEATH AND DIFFERENTIATION

p53 Degradation Activity, Expression, and Subcellular Localization of E6 Proteins from 29 Human Papillomavirus Genotypes

(2011) T. Mesplede et al.   JOURNAL OF VIROLOGY

Papillomavirus E5: the smallest oncoprotein with many functions

(2011) Aldo Venuti et al.   Molecular Cancer

Epstein-Barr Virus Nuclear Antigen 3C Stabilizes Gemin3 to Block p53-mediated Apoptosis

(2011) Qiliang Cai et al.   PLoS Pathogens

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

(2010) Chunling Yi et al.   BIOCHEMICAL PHARMACOLOGY

Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment

(2010) Mi-Kyung Kim et al.   BIOCHEMICAL PHARMACOLOGY

E6-Associated Protein Is Required for Human Papillomavirus Type 16 E6 to Cause Cervical Cancer in Mice

(2010) Anny Shai et al.   CANCER RESEARCH

E1^E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epithelium

(2010) P. B. McIntosh et al.   JOURNAL OF CELL SCIENCE

The Human Papillomavirus Type 16 E5 Oncoprotein Inhibits Epidermal Growth Factor Trafficking Independently of Endosome Acidification

(2010) Frank A. Suprynowicz et al.   JOURNAL OF VIROLOGY

Caspase-mediated protein kinase C-δ cleavage is necessary for apoptosis of vascular smooth muscle cells

(2009) Kaori Kato et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Human papillomavirus type 16 E5 protein inhibits hydrogen peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells

(2009) J.-M. Oh et al.   CARCINOGENESIS

Mapatumumab, a Fully Human Agonistic Monoclonal Antibody That Targets TRAIL-R1, in Combination with Gemcitabine and Cisplatin: a Phase I Study

(2009) C. H. Mom et al.   CLINICAL CANCER RESEARCH

The Full-Length Isoform of Human Papillomavirus 16 E6 and Its Splice Variant E6* Bind to Different Sites on the Procaspase 8 Death Effector Domain

(2009) S. S. Tungteakkhun et al.   JOURNAL OF VIROLOGY

The Human Papillomavirus (HPV) E6* Proteins from High-Risk, Mucosal HPVs Can Direct Degradation of Cellular Proteins in the Absence of Full-Length E6 Protein

(2009) D. Pim et al.   JOURNAL OF VIROLOGY

Case 10-2009

(2009) Mark A. Goldstein et al.   NEW ENGLAND JOURNAL OF MEDICINE

A novel interaction between the human papillomavirus type 16 E2 and E1^E4 proteins leads to stabilization of E2

(2009) Clare Davy et al.   VIROLOGY

Direct activation of caspase 8 by the proapoptotic E2 protein of HPV18 independent of adaptor proteins

(2008) F Thierry et al.   CELL DEATH AND DIFFERENTIATION

Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL)

(2008) Avi Ashkenazi et al.   JOURNAL OF CLINICAL ONCOLOGY

HIV-Specific Differences in Outcome of Squamous Cell Carcinoma of the Anal Canal: A Multicentric Cohort Study of HIV-Positive Patients Receiving Highly Active Antiretroviral Therapy

(2008) Christoph Oehler-Jänne et al.   JOURNAL OF CLINICAL ONCOLOGY

The Interaction between Human Papillomavirus Type 16 and FADD Is Mediated by a Novel E6 Binding Domain

(2008) S. S. Tungteakkhun et al.   JOURNAL OF VIROLOGY

Complexes of Human Papillomavirus Type 16 E6 Proteins Form Pseudo-Death-Inducing Signaling Complex Structures during Tumor Necrosis Factor-Mediated Apoptosis

(2008) M. Filippova et al.   JOURNAL OF VIROLOGY