Modulation of Apoptotic Signaling by the Hepatitis B Virus X Protein

Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein

(2012) Leo L. Studach et al.   HEPATOLOGY

Entry of Hepatitis B Virus into Immortalized Human Primary Hepatocytes by Clathrin-Dependent Endocytosis

(2012) H.-C. Huang et al.   JOURNAL OF VIROLOGY

Proteins ZNF198 and SUZ12 are down-regulated in hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replication

(2011) Wen-Horng Wang et al.   HEPATOLOGY

The X Protein of Hepatitis B Virus Inhibits Apoptosis in Hepatoma Cells through Enhancing the Methionine Adenosyltransferase 2A Gene Expression and ReducingS-Adenosylmethionine Production

(2011) Quanyan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell death and hepatocarcinogenesis: Dysregulation of apoptosis signaling pathways

(2011) Jorn Markus Schattenberg et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

(2011) Julie Lucifora et al.   JOURNAL OF HEPATOLOGY

HBx Sensitizes Cells to Oxidative Stress-induced Apoptosis by Accelerating the Loss of Mcl-1 Protein via Caspase-3 Cascade

(2011) Liang Hu et al.   Molecular Cancer

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair

(2011) F. Jiang et al.   PHARMACOLOGICAL REVIEWS

Transgenic Expression of Entire Hepatitis B Virus in Mice Induces Hepatocarcinogenesis Independent of Chronic Liver Injury

(2011) Bing Na et al.   PLoS One

Hepatitis B and C virus hepatocarcinogenesis: Lessons learned and future challenges

(2010) Michael J. Bouchard et al.   CANCER LETTERS

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice

(2010) M. Tsuge et al.   JOURNAL OF GENERAL VIROLOGY

The Hepatitis B Virus X Protein Modulates Hepatocyte Proliferation Pathways To Stimulate Viral Replication

(2010) T. L. Gearhart et al.   JOURNAL OF VIROLOGY

Apoptosis of Hepatitis B Virus-Infected Hepatocytes Prevents Release of Infectious Virus

(2010) S. Arzberger et al.   JOURNAL OF VIROLOGY

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures

(2010) A. Ploss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication of the hepatitis B virus requires a calcium-dependent HBx-induced G1 phase arrest of hepatocytes

(2010) Tricia L. Gearhart et al.   VIROLOGY

The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes

(2010) Tricia L. Gearhart et al.   VIRUS RESEARCH

HBx-induced reactive oxygen species activates hepatocellular carcinogenesisviadysregulation of PTEN/Akt pathway

(2010) Hye-Lin Ha   WORLD JOURNAL OF GASTROENTEROLOGY

Inflammation and Liver Cancer

(2009) C. Berasain et al.   Annals of the New York Academy of Sciences

HBx targeting to mitochondria and ROS generation are necessary but insufficient for HBV-induced cyclooxygenase-2 expression

(2009) Wonchung Lim et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Hepatitis B-related hepatocellular carcinoma: epidemiological characteristics and disease burden

(2009) V. T. T. Nguyen et al.   JOURNAL OF VIRAL HEPATITIS

Hepatitis B Virus X Protein Modulates Apoptosis in Primary Rat Hepatocytes by Regulating both NF- B and the Mitochondrial Permeability Transition Pore

(2009) A. J. Clippinger et al.   JOURNAL OF VIROLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection

(2008) Y. J. Yoon et al.   CARCINOGENESIS

Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1

(2008) Silvia Martin-Lluesma et al.   HEPATOLOGY

Hepatitis B virus X protein induces apoptosis by enhancing translocation of Bax to mitochondria

(2008) Hye Jin Kim et al.   IUBMB LIFE

Hepatitis B Virus X Protein via the p38MAPK Pathway Induces E2F1 Release and ATR Kinase Activation Mediating p53 Apoptosis

(2008) Wen-Horng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis B virus–cell interactions and pathogenesis

(2008) David H. Nguyen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hepatitis B Virus HBx Protein Localizes to Mitochondria in Primary Rat Hepatocytes and Modulates Mitochondrial Membrane Potential

(2008) A. J. Clippinger et al.   JOURNAL OF VIROLOGY

Genetic analysis of Dengue virus type 3 isolated in Buenos Aires, Argentina

(2008) Paola Roxana Barrero et al.   VIRUS RESEARCH

HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species

(2008) Jin-Mo Gu et al.   VIRUS RESEARCH

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY