Review
Biochemistry & Molecular Biology
Sulagna Dutta, Pallav Sengupta, Sanghamitra Das, Petr Slama, Shubhadeep Roychoudhury
Summary: Reactive nitrogen species (RNS) play important roles in male reproduction, but excessive levels can impair fertility by affecting testicular functions and compromising semen quality. High RNS levels lead to abnormalities in germ cells and gametes, and severely impact maturation and fertilization processes. Conventional semen analyses are not reliable predictors for assisted reproductive technology outcomes in cases of male infertility, highlighting the need for novel assessment and treatment methods.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Hao Hu, Bei Yan, Wei Zhang, Wenbo Yan, Liquan Liu, Xiaofeng Tang, Kejun Dong, Longjie Li, Xianjin Xiao, Chengliang Xiong
Summary: By constructing a single sperm ROS detection method (SSRDM) with an optical micro-probe, we can use ROS levels as an important indicator for the diagnosis and prognosis of male infertility. The SSRDM method utilizes fluorescence excitation in the sperm and surrounding area after ROS staining to reflect the ROS level in the sperm. Compared to flow cytometry, SSRDM has a stronger ability to distinguish between groups with different sperm motility, providing a reliable basis for assessing sperm quality.
CHINESE CHEMICAL LETTERS
(2023)
Article
Endocrinology & Metabolism
Jianing Niu, Qiurong Chang, Junting Xu, Jinli Li, Wenqiang Liu, Zhiqin Chen, Xianting Jiao, Yi Guo, Xiaoming Teng
Summary: This study aimed to identify the optimal oxidation-reduction level in the fertilization medium for IVF outcomes using the MiOXSYS system. It found that sORP values within the range of 228.7-235.3 mV were associated with better pregnancy outcomes and embryo quality.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Pharmacology & Pharmacy
Xiaonan Li, Donghui Cao, Siming Sun, Yuehui Wang
Summary: Dysregulation of reactive oxygen species (ROS) production and ROS-regulated pathways in cancer cells can have dual effects on cancer progression, either promoting transformation/proliferation or inducing cell death. Targeting ROS is a promising strategy for cancer treatment, and ginsenosides and related drug carriers have shown potential in modulating multiple signaling pathways to induce apoptosis, regulate cell cycle, invasion, and metastasis, and enhance drug sensitivity in different cancers. This review focuses on the pro- and anticancer effects of ROS and summarizes the mechanisms and recent advances in ginsenosides for anticancer therapy by targeting ROS, providing insights for future studies.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Andras Ballo, Kinga Busznyakne Szekvari, Peter Czetany, Laszlo Mark, Attila Torok, Arpad Szanto, Gabor Mate
Summary: According to estimates, at least 70% of feedstuffs and finished feeds are contaminated with mycotoxins, posing health risks and economic issues. Among these toxins, zearalenone (ZEA) and its derivatives have been found to have multiple negative effects on male reproductive cells. Studies have shown estrogenic effects of ZEA and discussed the impact on spermatogenesis, sperm cells, and reproductive health.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Endocrinology & Metabolism
Wei-Hui Shi, Mu-Jin Ye, Ning-Xin Qin, Zhi-Yang Zhou, Xuan-You Zhou, Nai-Xin Xu, Song-Chang Chen, Shu-Yuan Li, Chen-Ming Xu
Summary: Recent studies have shown that sperm mtDNA copy number, DNA fragmentation index, and reactive oxygen species content are important for sperm function. However, their associations with embryo development and pregnancy outcomes in assisted reproductive technology are still unclear.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cell Biology
Veronica Loyo-Celis, Gerardo Orta, Carmen Beltran, Alberto Darszon
Summary: Speract released from egg jelly regulates sea urchin sperm swimming through inducing chemotaxis and triggering changes in membrane potential, cyclic nucleotides, pH, and calcium concentration. CatSper, a sperm exclusive Ca2+ channel, has been identified in sea urchin sperm and is believed to be involved in chemotaxis. Electrophysiological characterization revealed a Na+ permeable channel resembling CatSper in sea urchin sperm, sensitive to speract and blocked by specific inhibitors.
Article
Ecology
Konstantinos Voulgaris, Anastasios Varkoulis, Stefanos Zaoutsos, Antonios Stratakis, Dimitris Vafidis
Summary: This study examined the mechanical properties of the test and spines of three sea urchin species in the Mediterranean, highlighting the robustness of S. granularis test and the flexibility of D. setosum spines. Porosity was found to play a key role in fracture prevention in the skeleton, with implications for defensive adaptations and invasive species strategies.
ECOLOGY AND EVOLUTION
(2021)
Article
Agriculture, Multidisciplinary
Yingxu Ma, Xincen Wang, Zhigao Wang, Peixu Cong, Jie Xu, Changhu Xue
Summary: The study characterized and semi-quantitated different SU-GLS subclasses in three sea urchin species, identifying a total of 14 subclasses and new SU-GLS structures. The research will provide valuable data for developing a SU-GLS database of aquatic products and a theoretical basis for exploring the nutritional values of seafood products further.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Marine & Freshwater Biology
Tihana Marceta, Lisa Locatello, Silvia Alban, Mohamad Sofi Abu Hassan, Nik-Nurasyikin Nik Mohmmad Azmi, Livio Finos, Denis Badocco, Maria Gabriella Marin
Summary: This study investigated the phenotypic changes of sperm and larvae of the sea urchin Paracentrotus lividus in response to different pH conditions experienced by the parents during gametogenesis. The research showed that offspring from parents exposed to low pH did not exhibit an increased ability to cope with ocean acidification.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Sinja Rist, Jessy Le Du-Carree, Kevin Ugwu, Chiara Intermite, Andrea Acosta-Dacal, Octavio Perez-Luzardo, Manuel Zumbado, May Gomez, Rodrigo Almeda
Summary: This study investigates the toxicity of tire particles and their leachates on early stages of echinoderm species. The results show that these particles can have negative effects on growth, development, and survival. Different species have different sensitivities to tire particle pollution, highlighting the importance of multi-species studies. More research and mitigation actions are needed to address the impact of these pollutants.
ENVIRONMENTAL POLLUTION
(2023)
Review
Plant Sciences
Vasily N. Popov, Mikhail Y. Syromyatnikov, Alisdair R. Fernie, Subhra Chakraborty, Kapuganti Jagadis Gupta, Abir U. Igamberdiev
Summary: Plant mitochondrial respiration involves various alternative pathways that are uncoupled from energy production, contributing to ROS and NO metabolism. These pathways play a crucial role in maintaining mitochondrial functions and rapid adaptation of plants to changing environmental factors.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Biochemistry & Molecular Biology
Chidozie N. Okoye, Don Stevens, Collins Kamunde
Summary: The study found that anoxia-reoxygenation and cadmium have different effects on H2O2 emission in fish liver mitochondria, depending on the substrate used, leading to different response patterns. Additionally, anoxia-reoxygenation inhibits mitochondrial respiration in a substrate-dependent manner.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Microbiology
Ruber Rodriguez-Barreras, Anelisse Dominicci-Maura, Eduardo L. Tosado-Rodriguez, Filipa Godoy-Vitorino
Summary: Caribbean sea urchins have experienced a decline in population. This study characterized the epibiota community associated with four wild Caribbean sea urchin species and evaluated the influence of species, trophic niches, and geographical location on the composition of the epibiotic microbiota. The results showed that the bacterial biota varied significantly among species and trophic niches, but not among geographical locations. The findings highlight the species-specific and niche-dependent nature of the epibiotic microbiota in sea urchins.
Article
Multidisciplinary Sciences
Dominic Franco C. Belleza, Takeshi Urae, Shin-ichiro Tanimae, Kento Toyama, Akari Isoda, Gregory N. Nishihara
Summary: In this study, the behaviors of three sea urchin species in temperate macroalgal forests were monitored in vegetated and adjacent bare habitats. The results showed that the behaviors of sea urchins varied depending on the benthic environment and physical conditions, which influenced their habitat preference and movement patterns.
