Article
Geriatrics & Gerontology
Stanislava Kosirova, Jana Urbankova, Jan Klimas, Tatiana Foltanova
Summary: This study assessed the use of potentially inappropriate medications (PIMs) among geriatric outpatients in the Slovak Republic and found that polypharmacy and overprescription of PIMs were prevalent issues. General practitioners prescribed significantly more drugs and PIMs compared to internists and geriatricians. The study also revealed that patients under the care of geriatricians had the lowest odds of being prescribed PIMs.
Article
Geriatrics & Gerontology
Lin-Na Chou, Yong-Fang Kuo, Mukaila A. Raji, James S. Goodwin
Summary: The study found that nurse practitioners (NPs) prescribed fewer initial PIMs and were less likely to refill a PIM after an outpatient visit than physicians. The odds of receiving PIMs during an NP visit varied by age, race/ethnicity, rurality, and number of comorbidities.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Medicine, General & Internal
Henrik Rudolf, Ulrich Thiem, Kaysa Aust, Dietmar Krause, Renate Klaassen-Mielke, Wolfgang Greiner, Hans J. Trampisch, Nina Timmesfeld, Petra Thuermann, Eike Hackmann, Tanja Barkhausen, Ulrike Junius-Walker, Stefan Wilm
Summary: The RIME trial aimed to investigate whether special training and the use of the PRISCUS card could reduce the occurrence of potentially inappropriate medications and undesired drug-drug interactions in elderly patients in primary care. However, the results showed that these interventions did not significantly lower the percentage of patients with PIM or DDI.
DEUTSCHES ARZTEBLATT INTERNATIONAL
(2021)
Article
Geriatrics & Gerontology
Elizabeth Manias, Cheng Hwee Soh, Md Zunayed Kabir, Esmee M. Reijnierse, Andrea B. Maier
Summary: The study found that potential prescribing omissions were associated with lower IADL scores at 3 months post-discharge from geriatric rehabilitation. There were no significant associations between potentially inappropriate medication use at admission and longitudinal changes of ADLs and IADLs. Renal potentially inappropriate medications were associated with higher IADL scores at 3 months post-discharge.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Pharmacology & Pharmacy
Alemayehu B. B. Mekonnen, Esmee M. M. Reijnierse, Cheng Hwee Soh, Wen Kwang Lim, Andrea B. B. Maier, Elizabeth Manias
Summary: This study investigates the associations between inappropriate prescribing and number of medications at discharge from geriatric rehabilitation with postdischarge health outcomes. The results show that inappropriate prescribing and higher number of medications are associated with readmission and mortality. Therefore, interventions are needed to improve appropriate prescribing in geriatric rehabilitation patients.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Geriatrics & Gerontology
Kati J. Auvinen, Johanna Raisanen, Ari Voutilainen, Johanna Jyrkka, Pekka Mantyselka, Eija Lonnroos
Summary: The study successfully improved medication quality among home care patients through inter professional medication assessment intervention, reducing medication-related risk loads and the odds of using potentially inappropriate medications.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Geriatrics & Gerontology
Joao Delgado, Lindsay Jones, Marie C. Bradley, Louise M. Allan, Clive Ballard, Linda Clare, Richard H. Fortinsky, Carmel M. Hughes, David Melzer
Summary: The study found that patients with dementia often receive potentially inappropriate prescribing (PIP), which increases the risk of adverse health outcomes such as mortality, skin issues, falls, anemia, and osteoporosis. This highlights the importance of optimizing medication in dementia patients, especially those with comorbidities.
Article
Geriatrics & Gerontology
Maria Tampaki, Alexandra Livada, Maria-Niki Fourka, Elli Lazaridou, Marina Kotsani, Athanase Benetos, Petros P. Sfikakis, Evrydiki Kravvariti
Summary: This study investigated the association between inappropriate prescriptions and adverse outcomes in older rural primary health care users. The START/STOPP tool was found to be useful in identifying inappropriate prescribing and its association with increased utilization of acute care services.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Anesthesiology
Kevin G. Burfeind, Yalda Zarnegarnia, Praveen Tekkali, Avital Y. O'Glasser, Joseph F. Quinn, Katie J. Schenning
Summary: The study found that perioperative PIM administration was common in older surgical patients, especially in frail patients, and was associated with increased hospital length of stay, but not with discharge disposition.
ANESTHESIA AND ANALGESIA
(2022)
Article
Pharmacology & Pharmacy
Feifei Wang, Guishui Xu, Chengting Rong, Xinan Wu
Summary: The Beers criteria, compared to the STOPP and EU criteria, were significantly associated with avoidable ADRs in hospitalized older persons.
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
(2021)
Article
Clinical Neurology
Peng Cui, Ting Liu, Zheng Wang, Shuaikang Wang, Peng Wang, Chao Kong, Shibao Lu
Summary: This study aimed to investigate the relationships between subcomponents of CGA and adverse events (AEs) in elderly patients undergoing posterior lumbar fusion surgery. The results showed that postoperative major AEs were associated with delirium, nutritional status, cognitive impairment, Charlson comorbidity index (CCI), and severe dependent. Screening for delirium, cognitive impairment, nutrition, and CCI preoperatively is essential to prevent postoperative major AEs in elderly surgical patients.
EUROPEAN SPINE JOURNAL
(2023)
Article
Infectious Diseases
Francoise Livio, Elisabeth Deutschmann, Giusi Moffa, Flamur Rrustemi, Felix Stader, Luigia Elzi, Dominique L. Braun, Alexandra Calmy, Anna Hachfeld, Matthias Cavassini, Philip E. Tarr, Kerstin Wissel, Manuel Battegay, Catia Marzolini
Summary: In this study, a high prevalence of polypharmacy and inappropriate prescribing was found in elderly individuals living with HIV. Common prescribing issues included incorrect dosage, lack of indication, and drugs not appropriate for the elderly. Risk factors for prescribing issues included polypharmacy, renal impairment, treatment with CNS-active drugs, and being female. Medication reconciliation and regular prescription reviews by experienced physicians are recommended to reduce polypharmacy and inappropriate prescribing in this vulnerable population.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Geriatrics & Gerontology
Abdallah Damin Abukhalil, Siham Al-Imam, Mohammad Yaghmour, Raghad Abushama, Laith Saad, Hiba Falana, Hani A. Naseef
Summary: This study investigated the medication use among elderly patients in two Palestinian hospitals and found a high prevalence of potentially inappropriate medication use and prescribing omissions. The study also highlighted the high prevalence of polypharmacy. The results emphasize the importance of using evidence-based tools to optimize patient medication therapy.
CLINICAL INTERVENTIONS IN AGING
(2022)
Article
Medicine, General & Internal
Goran Stojanovic, Dugan Djuric, Biljana Jakovljevic, Tamara Turnic Nikolic, Milena Maricic, Svetlana Stojanovic, Olivera Milovanovic
Summary: With the growing number of older adults, there is an increased use of medication. This study aimed to determine the frequency and identify risk factors of potentially inappropriate medication (PIM) in elderly patients with cardiovascular diseases. The results showed that the frequency of PIM in the elderly population was 70.3%, with a higher prevalence in female elders.
VOJNOSANITETSKI PREGLED
(2022)
Article
Multidisciplinary Sciences
Toshihiro Tanaka, Rika Sakai, Ilseung Choi, Junichi Tsukada, Hidenori Sasaki, Yoshiko Naito, Fumiaki Kiyomi, Yasushi Takamatsu, Kazuo Tamura
Summary: A comprehensive geriatric assessment (CGA) may be a useful tool for predicting serious adverse events (AEs) associated with chemotherapy in elderly patients with diffuse large B-cell lymphoma (DLBCL). According to this study, impairment of instrumental activities of daily living (IADL) in the CGA was independently associated with severe leukopenia and anemia. The presence of comorbidity was also associated with severe non-hematological toxicity. Additionally, the independent group tended to have a longer survival rate.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
J. Sausmikat, M. Smollich
KLINISCHE PADIATRIE
(2016)
Editorial Material
Medicine, General & Internal
Torsten Schroder, Alina Kistenmacher, Martin Smollich, Christian Sina
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT
(2018)
Article
Multidisciplinary Sciences
Jacklien H. J. Maessen, Jorg Raab, Manon Haverkate, Martin Smollich, Henriette L. G. ter Waarbeek, Renske Eilers, Aura Timen
Article
Public, Environmental & Occupational Health
Lara Jablonowski, Joachim Gardemann, Martin Smollich, Thorsten Kuczius
Summary: The study found that there was no clear vaccination gap among (school) children of refugee families, but they still faced challenges in integrating into the local outpatient care system, including inadequate vaccination education, language barriers, and frequent relocations. The vaccination engagement and behavior of refugees were generally positive, but more attention should be paid to international standards, such as the sphere standards, in practical implementation within refugee relief programs.
Article
Nutrition & Dietetics
Anna Kordowski, Axel Kuenstner, Lisa Schweitzer, Stephan Theis, Torsten Schroeder, Hauke Busch, Christian Sina, Martin Smollich
Summary: This study examines the impact of incorporating isomaltulose and ITF into the habitual diet on glycemic control and gut microbiota. Results show that isomaltulose-sweetened drinks lead to lower postprandial glycemia compared to sucrose-sweetened drinks. Furthermore, ITF supplementation improves glucose control and positively modulates gut microbiota. The study suggests interindividual differences in glycemic response to ingredients and a possible relationship between gut microbiota and glycemic response.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Jasmin Ostermann, Martin Smollich
Summary: This study investigates the importance of nutrition for the treatment and recurrence prevention of breast cancer, and finds a discrepancy between nutritional needs and actual care. Most patients expressed a desire for nutritional counseling, but few actually received it. The implementation of qualified nutritional counseling for breast cancer patients is urgently needed to optimize nutritional status and avoid potentially dangerous interactions with dietary supplements.
AKTUELLE ERNAHRUNGSMEDIZIN
(2022)
Article
Nutrition & Dietetics
Merle Roeren, Anna Kordowski, Christian Sina, Martin Smollich
Summary: This study investigated the choline intake of pregnant women in Germany and found that the majority did not meet the adequate intake. Omnivores had a significantly higher intake than vegetarians/vegans. There is a need to improve choline supply for pregnant women.
Article
Nutrition & Dietetics
Anna Kordowski, Vivian Valeska Tetzlaff-Lelleck, Bodo Speckmann, Gunnar Loh, Axel Kunstner, Franziska Schulz, Torsten Schroder, Martin Smollich, Christian Sina, Heike Tom Dieck
Summary: This study found that a synbiotic-based formulation can effectively lower blood glucose levels and has a significant effect on weight reduction, especially in individuals with higher pre-supplementation blood glucose and HbA1c levels. This study suggests that the formulation is an effective and convenient approach to counteract hyperglycemia.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Stefanie Hartwig, Christian Sina, Martin Smollich
Summary: This review article explores the legal issues related to vegan and vegetarian animal substitutes, including food composition and product labeling. In Germany, the non-legally binding definition provided by the German Food Book Commission's guidelines is used due to the absence of a legal definition. When labeling and marketing such products, general food law regulations, particularly misleading regulations and requirements for protecting dairy product designations, must also be considered.
AKTUELLE ERNAHRUNGSMEDIZIN
(2022)
Article
Nutrition & Dietetics
Stefan Senekowitsch, Eliza Wietkamp, Michael Grimm, Franziska Schmelter, Philipp Schick, Anna Kordowski, Christian Sina, Hans Otzen, Werner Weitschies, Martin Smollich
Summary: This study investigated the pharmacokinetics of oral spermidine supplementation for the first time, and found that spermidine supplementation significantly increased plasma spermine levels, while it did not affect spermidine or putrescine levels. This suggests that dietary spermidine is converted into spermine and contributes to the in vitro and clinical effects of spermidine.
Article
Communication
Martin Smollich, Lea Tischner
Summary: This study reveals the existence of a connection between diet and acne, but due to a lack of nutritional consultation from dermatologists, patients seek additional sources of information. Many participants feel that their nutritional interventions are unsuccessful and believe there is an information gap.
FRONTIERS IN COMMUNICATION
(2022)
Article
Medicine, General & Internal
Martin Smollich
AKTUELLE ERNAHRUNGSMEDIZIN
(2021)
Article
Medicine, General & Internal
Katharina Schlumm, Christian Sina, Torsten Schroeder, Martin Smollich
AKTUELLE ERNAHRUNGSMEDIZIN
(2019)
Article
Obstetrics & Gynecology
Isabel Radke, Martin Goette, Martin Smollich, Ninette Scharle, Ludwig Kiesel, Pia Wuelfing
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2017)
Article
Medicine, General & Internal
Martin Smollich
AKTUELLE ERNAHRUNGSMEDIZIN
(2017)
