Journal
ZEITSCHRIFT FUR GASTROENTEROLOGIE
Volume 48, Issue 6, Pages 693-695Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0028-1109814
Keywords
lymphocytic colitis; duloxetine; adverse drug effects
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Lymphocytic colitis is a disease characterised by chronic watery diarrhoea that can only be diagnosed histologically, since colonoscopy reveals macroscopically normal mucosa. A causal relationship to the administration of certain drugs has repeatedly been described. In this report we describe a case of lymphocytic colitis that developed after initiation of treatment with duloxetine - a selective serotonin- and noradrenaline-reuptake inhibitor - and remitted after discontinuation of the drug. Since a causal relationship between the onset of lymphocytic colitis and the use of duloxetine is highly probable, duloxetine should be included among those drugs capable of inducing lymphocytic colitis.
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