4.2 Article

Day-to-Day Differences in Cortisol Levels and Molar Cortisol-to-DHEA Ratios among Working Individuals

Journal

YONSEI MEDICAL JOURNAL
Volume 51, Issue 2, Pages 212-218

Publisher

YONSEI UNIV COLL MEDICINE
DOI: 10.3349/ymj.2010.51.2.212

Keywords

Salivary cortisol; salivary DHEA; weekly cortisol rhythm; weekly molar cortisol-to-DHEA ratio rhythm; working individuals

Funding

  1. Korean Government (MOEHRD) [KRF-2006-005-J03001]
  2. National Research Foundation of Korea [과06B1308] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

Ask authors/readers for more resources

Purpose: The present study was carried out to determine day-to-day differences in cortisol levels and the molar cortisol-to-dehydroepiandrosterone (DHEA) ratio (molar C/D ratio) in working subjects. Materials and Methods: The cortisol and DHEA levels were measured from saliva samples collected 30 minutes after awakening for 7 consecutive days in full-time working subjects that worked Monday through Saturday. To determine the day-to-day differences within subjects, the collected data was analyzed using variance (ANOVA) for a randomized complete block design (RCBD). Results: The cortisol levels from samples collected 30 minutes after awakening on workdays were similar to each other, but were significantly different from the cortisol levels on Sunday. The DHEA levels were not significantly different between the days of week. The DHEA levels on Monday and Tuesday were relatively lower than the levels on the other weekdays. The DHEA levels on Thursday and Friday were relatively higher than the other days. The molar C/D ratios on Sunday were significantly lower than those on workdays. The molar C/D ratios on Monday and Tuesday were significantly higher than those on Wednesday or other workdays. Conclusion: The cortisol levels and the molar C/D ratios demonstrate differences in adrenocortical activities between workdays and non-workdays, but the molar C/D ratio additionally represents differences in adrenocortical status between the first two workdays and other workdays. Thus, it is possible that the day-to-day differences in the cortisol levels and the molar CID ratio represent the adrenal response to upcoming work-related stress.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Endocrinology & Metabolism

Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders

Kyung B. Jo, Young Lee, Il G. Lee, Sang C. Lee, Jai Y. Park, Ryun S. Ahn

PSYCHONEUROENDOCRINOLOGY (2016)

Article Endocrinology & Metabolism

Molecular cloning and expression of steroidogenic acute regulatory protein from bullfrog (Rana catesbeiana)

Seung-Chang Kim, Sung-Dug Oh, Ryun-Sup Ahn, Jaemog Soh, Hyuk-Bang Kwon

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2009)

Article Biochemistry & Molecular Biology

Insulin Directly Regulates Steroidogenesis via Induction of the Orphan Nuclear Receptor DAX-1 in Testicular Leydig Cells

Seung Won Ahn, Gil-Tae Gang, Yong Deuk Kim, Ryun-Sup Ahn, Robert A. Harris, Chul-Ho Lee, Hueng-Sik Choi

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Endocrinology & Metabolism

Cortisol, estradiol-17β, and progesterone secretion within the first hour after awakening in women with regular menstrual cycles

Ryun S. Ahn, Jee H. Choi, Bum C. Choi, Jung H. Kim, Sung H. Lee, Simon S. Sung

JOURNAL OF ENDOCRINOLOGY (2011)

Article Biochemistry & Molecular Biology

Reduced testicular steroidogenesis in tumor necrosis factor-α knockout mice

Ji Ho Suh, Eun-Yeung Gong, Cheol Yi Hong, Eunsook Park, Ryun Sup Ahn, Kwang Sung Park, Keesook Lee

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2008)

Article Multidisciplinary Sciences

Transforming Growth Factor-β1 Signaling Represses Testicular Steroidogenesis through Cross-Talk with Orphan Nuclear Receptor Nur77

Eunsook Park, Chin-Hee Song, Jae-Il Park, Ryun-Sup Ahn, Hueng-Sik Choi, CheMyong Ko, Keesook Lee

PLOS ONE (2014)

Article Endocrinology & Metabolism

Hypothalamic-pituitary-adrenal axis function in patients with complex regional pain syndrome type 1

Jai Y. Park, Ryun S. Ahn

PSYCHONEUROENDOCRINOLOGY (2012)

Article Behavioral Sciences

Abnormal diurnal pattern of cortisol secretion in patients after aneurysmal subarachnoid hemorrhage

Il Y. Shin, Hye M. Joo, Yong G. Chung, Min S. Kim, Jung W. Park, Ryun S. Ahn

STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2011)

Article Medicine, General & Internal

Cortisol Awakening Response and Nighttime Salivary Cortisol Levels in Healthy Working Korean Subjects

Il-young Shin, Ryun-sup Ahn, Sae-il Chun, Young-jin Lee, Min-soo Kim, Chea-kwan Lee, Simon Sung

YONSEI MEDICAL JOURNAL (2011)

Article Behavioral Sciences

Association of the HPA axis response to upcoming competition and shooting outcomes in elite junior shooting players

Jae-Koo Lee, Jae-Koo Park, Hoon Kim, Jung-Yim Kang, Jai-Young Park, Sang-Hwan Do, Ryun-Sup Ahn

STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2020)

Article Psychiatry

Relationship of Resilience Factors With Biopsychosocial Markers Using a Comprehensive Home Evaluation Kit for Depression and Suicide Risk: A Real-World Data Analysis

Sooah Jang, Sun-Woo Choi, Ryunsup Ahn, Ju-Yeal Lee, Joohan Kim, Jeong-Ho Seok

Summary: This study developed a home evaluation kit to assess bio-psycho-social factors related to depression and suicide. The results suggest that insecure attachment and mentalization problems negatively affect resilience. In groups with ACE, mentalization problems were found to increase depressive symptoms. AUCg showed potential as a biomarker for resilience and vulnerability factors of depression.

FRONTIERS IN PSYCHIATRY (2022)

Article Endocrinology & Metabolism

The Involvement of the Hypothalamus-Pituitary-Adrenal Axis in the Development of Hyperalgesia During the Early Postoperative Period in Postmenopausal Patients

Ryun S. Ahn, Jin-Woo Park, In-Sun Park, Hyun-Jung Shin, Jung-Hee Ryu, Ah-Young Oh, Hee-Yeon Park, Sang-Hwan Do

Summary: This study found that HPA axis function after surgery may be involved in the development of postoperative hyperalgesia. Adrenocortical steroidogenic activity favoring the production of cortisol over DHEA may contribute to the development of hyperalgesia.

NEUROENDOCRINOLOGY (2023)

Article Psychiatry

Virtual reality-based monitoring test for MCI: A multicenter feasibility study

Sooah Jang, Sun-Woo Choi, Sang Joon Son, Jooyoung Oh, Junghee Ha, Woo Jung Kim, Hyun Woong Roh, Keun You Kim, San Lee, Eunjin Jung, Woojin Cha, Heonjoo Chae, Suzi Kang, Ji Hye Kwon, In-Young Kim, Ju-Yeal Lee, Hyun Kyung Shin, Jin Sun Ryu, Ryunsup Ahn, Chang Hyung Hong, Jeong-Ho Seok

Summary: This study aimed to determine the efficacy and usability of a VR cognitive assessment program and salivary DHEA for screening MCI. The results showed that the VR cognitive test was as effective as the traditional MOCA test in the MCI classification and safe enough for older adults to perform, indicating its potential as a diagnostic tool. Additionally, salivary DHEA can serve as a biomarker for MCI.

FRONTIERS IN PSYCHIATRY (2023)

Article Environmental Sciences

Effects of butyltin compounds on follicular steroidogenesis in the bullfrog(Rana catesbeiana)

Ryun Sup Ahn, Seong-Jeong Han, Seung Chang Kim, Hyuk Bang Kwon

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2007)

No Data Available