Genetic interactions of yeast NEP1 (EMG1), encoding an essential factor in ribosome biogenesis

Structure of the no-go mRNA decay complex Dom34–Hbs1 bound to a stalled 80S ribosome

(2011) Thomas Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

(2011) Beate Schwer et al.   NUCLEIC ACIDS RESEARCH

Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis inSaccharomyces cerevisiae

(2011) Juan José García-Gómez et al.   RNA Biology

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins

(2011) Tanja Scherrer et al.   GENOME BIOLOGY

EMG1 is essential for mouse pre-implantation embryo development

(2010) Xiaoli Wu et al.   BMC DEVELOPMENTAL BIOLOGY

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

(2010) Batool Ossareh-Nazari et al.   EMBO REPORTS

Why Dom34 Stimulates Growth of Cells with Defects of 40S Ribosomal Subunit Biosynthesis

(2010) A. Bhattacharya et al.   MOLECULAR AND CELLULAR BIOLOGY

A Consensus of Core Protein Complex Compositions for Saccharomyces cerevisiae

(2010) Joris J. Benschop et al.   MOLECULAR CELL

Structure of the Dom34–Hbs1 complex and implications for no-go decay

(2010) Liming Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

(2010) Seth R. Thomas et al.   NUCLEIC ACIDS RESEARCH

The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase

(2010) Jan Philip Wurm et al.   NUCLEIC ACIDS RESEARCH

The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA

(2010) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

Crystal Structure of the Eukaryotic Ribosome

(2010) A. Ben-Shem et al.   SCIENCE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1

(2010) J. Rabl et al.   SCIENCE

Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome

(2009) Joy Armistead et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Driving ribosome assembly

(2009) Dieter Kressler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii

(2009) Jan Philip Wurm et al.   Biomolecular NMR Assignments

A Convergence of rRNA and mRNA Quality Control Pathways Revealed by Mechanistic Analysis of Nonfunctional rRNA Decay

(2009) Sarah E. Cole et al.   MOLECULAR CELL

Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing

(2009) X.-h. Liang et al.   RNA

Comprehensive Molecular Structure of the Eukaryotic Ribosome

(2009) Derek J. Taylor et al.   STRUCTURE

Bioinformatic identification of novel methyltransferases

(2009) Tanya Petrossian et al.   Epigenomics

Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status

(2008) Akiko Murayama et al.   CELL

A Genetic Interaction Map of RNA-Processing Factors Reveals Links between Sem1/Dss1-Containing Complexes and mRNA Export and Splicing

(2008) Gwendolyn M. Wilmes et al.   MOLECULAR CELL

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site

(2008) A. B. Taylor et al.   NUCLEIC ACIDS RESEARCH