Islet xenotransplantation: what is the optimal age of the islet-source pig?

Quality of Isolated Pig Islets is Improved Using Perfluorohexyloctane for Pancreas Storage in a Split Lobe Model

(2013) H. Brandhorst et al.   CELL TRANSPLANTATION

In Vitro Maturation of Viable Islets from Partially Digested Young Pig Pancreas

(2013) Morgan Lamb et al.   CELL TRANSPLANTATION

Islet xenotransplantation from genetically engineered pigs

(2013) Santosh Nagaraju et al.   Current Opinion in Organ Transplantation

A lectin microarray study of glycoantigens in neonatal porcine islet-like cell clusters

(2013) Akira Maeda et al.   JOURNAL OF SURGICAL RESEARCH

Omentum Is Better Site Than Kidney Capsule for Growth, Differentiation, and Vascularization of Immature Porcine β-Cell Implants in Immunodeficient Rats

(2013) Kim Bartholomeus et al.   TRANSPLANTATION

Evidence of safety and efficacy of two forms of neonatal cell transplants

(2013) Robert B. Elliott et al.   XENOTRANSPLANTATION

Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model

(2013) Jamie L. Brady et al.   XENOTRANSPLANTATION

Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation

(2013) Andrew J. Lutz et al.   XENOTRANSPLANTATION

Differences in glucose-stimulated insulin secretionin vitroof islets from human, nonhuman primate, and porcine origin

(2013) Kate R Mueller et al.   XENOTRANSPLANTATION

Alternative Immunomodulatory Strategies for Xenotransplantation: CD40/154 Pathway-Sparing Regimens Promote Xenograft Survival

(2012) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Early Islet Damage after Direct Exposure of Pig Islets to Blood: Has Humoral Immunity Been Underestimated?

(2012) Dirk J. Van Der Windt et al.   CELL TRANSPLANTATION

Xenografted Islet Cell Clusters From INSLEA29Y Transgenic Pigs Rescue Diabetes and Prevent Immune Rejection in Humanized Mice

(2012) N. Klymiuk et al.   DIABETES

Clinical Islet Xenotransplantation: How Close Are We?

(2012) D. J. van der Windt et al.   DIABETES

Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice

(2012) Shounan Yi et al.   DIABETES

Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010

(2012) F. B. Barton et al.   DIABETES CARE

Functional improvement of porcine neonatal pancreatic cell clustersviaconformal encapsulation using an air-driven encapsulator

(2012) Sol Ji Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

A humanized mouse model to study human immune response in xenotransplantation

(2012) Ming Ji et al.   Hepatobiliary & Pancreatic Diseases International

Conformal polymer coatings for pancreatic islets transplantation

(2012) Paolo Blasi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Study of the Glycoantigens of Neonatal Porcine Islet-Like Cell Clusters Using a Lectin Microarray

(2012) S. Nakatsu et al.   TRANSPLANTATION PROCEEDINGS

Real-time assessment of encapsulated neonatal porcine islets prior to clinical xenotransplantation

(2012) Jennifer P. Kitzmann et al.   XENOTRANSPLANTATION

Development of a novel xenotransplantation strategy for treatment of diabetes mellitus in rat hosts and translation to non-human primates

(2012) Marc R. Hammerman   Organogenesis

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CD40-Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Tissue Factor Knockdown in Porcine Islets: An Effective Approach to Suppressing the Instant Blood-Mediated Inflammatory Reaction

(2011) Xiaoqian Ma et al.   CELL TRANSPLANTATION

Towards xenotransplantation of pig islets in the clinic

(2011) Robert B Elliott   Current Opinion in Organ Transplantation

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

(2011) Goodarz Danaei et al.   LANCET

Protection of Porcine Islet Xenografts in Mice Using Sertoli Cells and Monoclonal Antibodies

(2011) Qahir A. Ramji et al.   TRANSPLANTATION

Reduced Progression of Diabetic Microvascular Complications With Islet Cell Transplantation Compared With Intensive Medical Therapy

(2011) David M. Thompson et al.   TRANSPLANTATION

Species incompatibilities in the pig-to-macaque islet xenotransplant model affect transplant outcome: a comparison with allotransplantation

(2011) Melanie L. Graham et al.   XENOTRANSPLANTATION

Pig islet for xenotransplantation in human: structural and physiological compatibility for human clinical application

(2011) Denis Dufrane et al.   Transplantation Reviews

Long-term follow-up of patients with type 1 diabetes transplanted with neonatal pig islets

(2010) R. Valdes-Gonzalez et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Short-Term Administrations of a Combination of Anti-LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice

(2010) H. Arefanian et al.   DIABETES

Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates up to 6 Months Without Immunosuppression

(2010) Denis Dufrane et al.   TRANSPLANTATION

Long-Term Controlled Normoglycemia in Diabetic Non-Human Primates After Transplantation with hCD46 Transgenic Porcine Islets

(2009) D. J. van der Windt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Prolonged Survival of Microencapsulated Neonatal Porcine Islet Xenografts in Immune-Competent Mice without Antirejection Therapy

(2009) Tsunehiro Kobayashi et al.   CELL TRANSPLANTATION

Pig Embryonic Pancreatic Tissue as a Source for Transplantation in Diabetes: Transient Treatment With Anti-LFA1, Anti-CD48, and FTY720 Enables Long-Term Graft Maintenance in Mice With Only Mild Ongoing Immunosuppression

(2009) D. Tchorsh-Yutsis et al.   DIABETES

Islet Isolation from the Pancreas of Large Mammals and Humans: 10 Years of Experience

(2009) Daniel Brandhorst et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Pancreas transplantation

(2009) Steve A White et al.   LANCET

Embryonic pig pancreatic tissue for the treatment of diabetes in a nonhuman primate model

(2009) G. Hecht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parameters for successful pig islet isolation as determined using 68 specific-pathogen-free miniature pigs

(2009) Hyoung-Il Kim et al.   XENOTRANSPLANTATION

Cobalt Protoporpyhrin Reduces Caspase-3,-7 Enzyme Activity in Neonatal Porcine Islets, But Does Not Inhibit Cell Death Induced by TNF-α

(2008) Erika Bosio et al.   CELL TRANSPLANTATION

What strain of pig should be used?

(2008) Sangeetha Prabhakaran et al.   XENOTRANSPLANTATION

What type of islets should be used?

(2008) Gregory S. Korbutt   XENOTRANSPLANTATION