Comparative pharmacokinetics of Nω-hydroxy-nor-L-arginine, an arginase inhibitor, after single-dose intravenous, intraperitoneal and intratracheal administration to brown Norway rats

Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats

(2011) Julia Grönros et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Increased arginase activity contributes to airway remodelling in chronic allergic asthma

(2011) H. Maarsingh et al.   EUROPEAN RESPIRATORY JOURNAL

HPLC determination of arginases inhibitor N-(ω)-hydroxy-nor-l-arginine using core–shell particle column and LC–MS/MS identification of principal metabolite in rat plasma

(2011) Miloš Hroch et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model

(2010) Noriko Takahashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibition of human arginase I by substrate and product analogues

(2010) Luigi Di Costanzo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Reduction ofNω-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC)

(2010) Jürke Kotthaus et al.   BIOCHEMICAL JOURNAL

Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension

(2010) Teddy Bagnost et al.   CARDIOVASCULAR RESEARCH

Endothelial arginase II responds to pharmacological inhibition by elevation in protein level

(2010) Karina Krotova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Species differences in expression pattern of arginase isoenzymes and differential effects of arginase inhibition on collagen synthesis in human and rat pulmonary fibroblasts

(2010) M. Warnken et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Arginase 1 and arginase 2 variations associate with asthma, asthma severity and β2 agonist and steroid response

(2010) Judith M. Vonk et al.   Pharmacogenetics and Genomics

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma

(2009) Michelle L. North et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

(2009) Harm Maarsingh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Arginase inhibition mediates cardioprotection during ischaemia-reperfusion

(2009) C. Jung et al.   CARDIOVASCULAR RESEARCH

Treatment with the arginase inhibitor Nω-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat

(2009) Teddy Bagnost et al.   JOURNAL OF HYPERTENSION

Arginase inhibition in airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin

(2009) Jennifer M. Bratt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arginase Inhibition Protects against Allergen-induced Airway Obstruction, Hyperresponsiveness, and Inflammation

(2008) Harm Maarsingh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Arginase and vascular aging

(2008) Lakshmi Santhanam et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Fourth Molybdenum Containing Enzyme mARC: Cloning and Involvement in the Activation ofN-Hydroxylated Prodrugs

(2008) Sanja Gruenewald et al.   JOURNAL OF MEDICINAL CHEMISTRY

Arginase blockade protects against hepatic damage in warm ischemia-reperfusion

(2008) Geetha Jeyabalan et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Functional role and species-specific contribution of arginases in pulmonary fibrosis

(2007) Kamila Kitowska et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY