Assessment of immunotoxicity using precision-cut tissue slices

LPS-Induced Lung Inflammation in Marmoset Monkeys – An Acute Model for Anti-Inflammatory Drug Testing

(2012) Sophie Seehase et al.   PLoS One

Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis

(2010) Courtney S. Schaffert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Present and future ofin vitroimmunotoxicology in drug development

(2010) Valentina Galbiati et al.   Journal of Immunotoxicology

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

(2010) Inge A M de Graaf et al.   Nature Protocols

Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices

(2010) S. Switalla et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration

(2009) Maria Montero et al.   BRAIN RESEARCH

Low cytotoxicity of solid lipid nanoparticles inin vitroandex vivolung models

(2009) Matthias Nassimi et al.   INHALATION TOXICOLOGY

Resistin Is More Abundant in Liver Than Adipose Tissue and Is Not Up-Regulated by Lipopolysaccharide

(2009) Ewa Szalowska et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Innate immune response to H3N2 and H1N1 influenza virus infection in a human lung organ culture model

(2009) Wenxin Wu et al.   VIROLOGY

Endotoxin Augments Myeloid Dendritic Cell Influx into the Airways in Patients with Allergic Asthma

(2008) Frank Schaumann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane

(2008) Natalya Hanlon et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Steroids completely reverse albuterol-induced β 2 -adrenergic receptor tolerance in human small airways

(2008) Philip R. Cooper et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chemical respiratory allergy and occupational asthma: what are the key areas of uncertainty?

(2008) Daniel Isola et al.   JOURNAL OF APPLIED TOXICOLOGY

Differential Sensitivity of Differentiated Epithelial Cells to Respiratory Viruses Reveals Different Viral Strategies of Host Infection

(2008) K. Goris et al.   JOURNAL OF VIROLOGY

Bacillus anthracis Peptidoglycan Stimulates an Inflammatory Response in Monocytes through the p38 Mitogen-Activated Protein Kinase Pathway

(2008) Marybeth Langer et al.   PLoS One

Airway mechanics and methods used to visualize smooth muscle dynamics in vitro

(2008) P.R. Cooper et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Ex Vivo Lung Function Measurements in Precision-Cut Lung Slices (PCLS) from Chemical Allergen–Sensitized Mice Represent a Suitable Alternative to In Vivo Studies

(2008) M. Henjakovic et al.   TOXICOLOGICAL SCIENCES

Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity

(2008) M ELFERINK et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ex vivo testing of immune responses in precision-cut lung slices

(2008) M. Henjakovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Liver slices as a model to study fibrogenesis and test the effects of anti-fibrotic drugs on fibrogenic cells in human liver

(2008) M. van de Bovenkamp et al.   TOXICOLOGY IN VITRO

Respiratory sensitization and allergy: Current research approaches and needs

(2007) Darrell R. Boverhof et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size

(2007) Daphnee S. Pushparajah et al.   TOXICOLOGY IN VITRO