Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips

Metabolomics-on-a-Chip and Predictive Systems Toxicology in Microfluidic Bioartificial Organs

(2012) Laetitia Shintu et al.   ANALYTICAL CHEMISTRY

Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions

(2012) Shu Cheng et al.   BMC GENOMICS

Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells

(2012) Djomangan Adama Ouattara et al.   Molecular BioSystems

Improvement of HepG2/C3a cell functions in a microfluidic biochip

(2011) Jean Matthieu Prot et al.   BIOTECHNOLOGY AND BIOENGINEERING

A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening

(2011) Jean-Matthieu Prot et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Integrated Proteomic and Transcriptomic Investigation of the Acetaminophen Toxicity in Liver Microfluidic Biochip

(2011) Jean Matthieu Prot et al.   PLoS One

Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor

(2010) Régis Baudoin et al.   BIOCHEMICAL ENGINEERING JOURNAL

A robust high-throughput sandwich cell-based drug screening platform

(2010) Shufang Zhang et al.   BIOMATERIALS

Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans

(2010) Orianne Videau et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

(2009) P. Chao et al.   BIOCHEMICAL PHARMACOLOGY

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

(2009) Eric Novik et al.   BIOCHEMICAL PHARMACOLOGY

Chemical regulators have overreached

(2009) Thomas Hartung et al.   NATURE

Inhibition and induction of human cytochrome P450 enzymes: current status

(2008) Olavi Pelkonen et al.   ARCHIVES OF TOXICOLOGY

Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes

(2008) S. W. Paine et al.   DRUG METABOLISM AND DISPOSITION