N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases

UGT2B10 Genotype Influences Nicotine Glucuronidation, Oxidation, and Consumption

(2010) J. Z. Berg et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Role of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and Trimipramine

(2010) D. Zhou et al.   DRUG METABOLISM AND DISPOSITION

Influence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10

(2009) O. Kerdpin et al.   DRUG METABOLISM AND DISPOSITION

Quantitative Analysis of UDP-Glucuronosyltransferase (UGT) 1A and UGT2B Expression Levels in Human Livers

(2009) T. Izukawa et al.   DRUG METABOLISM AND DISPOSITION

Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system

(2009) Michael H. Court   DRUG METABOLISM REVIEWS

Nicotine Metabolism in African Americans and European Americans: Variation in Glucuronidation by Ethnicity and UGT2B10 Haplotype

(2009) J. Z. Berg et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3

(2009) Nina Sneitz et al.   Pharmacogenetics and Genomics

The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan

(2008) Anna Alonen et al.   BIOCHEMICAL PHARMACOLOGY

Local Kinetics and Dynamics of Xenobiotics

(2008) Olavi Pelkonen et al.   CRITICAL REVIEWS IN TOXICOLOGY

Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10

(2008) G. Chen et al.   DRUG METABOLISM AND DISPOSITION

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

(2008) S. Ohno et al.   DRUG METABOLISM AND DISPOSITION

Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans

(2008) S. Klieber et al.   DRUG METABOLISM AND DISPOSITION

Prediction of Drug Clearance by Glucuronidation from in Vitro Data: Use of Combined Cytochrome P450 and UDP-Glucuronosyltransferase Cofactors in Alamethicin-Activated Human Liver Microsomes

(2008) P. J. Kilford et al.   DRUG METABOLISM AND DISPOSITION

The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of  -Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases

(2008) K. Itaaho et al.   DRUG METABOLISM AND DISPOSITION

Regio- and Stereospecific N-Glucuronidation of Medetomidine: The Differences between UDP Glucuronosyltransferase (UGT) 1A4 and UGT2B10 Account for the Complex Kinetics of Human Liver Microsomes

(2008) S. Kaivosaari et al.   DRUG METABOLISM AND DISPOSITION

Species Differences in UDP-Glucuronosyltransferase Activities in Mice and Rats

(2008) H. Shiratani et al.   DRUG METABOLISM AND DISPOSITION

UDP-Glucuronosyltransferases (UGTs) 2B7 and UGT2B17 Display Converse Specificity in Testosterone and Epitestosterone Glucuronidation, whereas UGT2A1 Conjugates Both Androgens Similarly

(2008) T. Sten et al.   DRUG METABOLISM AND DISPOSITION

Novel Polymorphic Human UDP-glucuronosyltransferase 2A3: Cloning, Functional Characterization of Enzyme Variants, Comparative Tissue Expression, and Gene Induction

(2008) M. H. Court et al.   MOLECULAR PHARMACOLOGY

Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines

(2008) Gang Chen et al.   Pharmacogenetics and Genomics