Use of primary rat hepatocytes in the gel entrapment culture to predictin vivobiliary excretion

Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes

(2011) Jacob Kramer Jacobsen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Expressions of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in lung dendritic cells

(2011) Hirotsugu Hasegawa et al.   LIFE SCIENCES

Selenium-dependent and -independent transport of arsenic by the human multidrug resistance protein 2 (MRP2/ABCC2): implications for the mutual detoxification of arsenic and selenium

(2010) M. W. Carew et al.   CARCINOGENESIS

Molecular Mechanisms of Biliary Excretion of Cefditoren and the Effects of Cefditoren on the Expression Levels of Hepatic Transporters

(2010) Qiang Meng et al.   Drug Metabolism and Pharmacokinetics

Dose-Dependent Inhibition of Transporter-Mediated Hepatic Uptake and Biliary Excretion of Methotrexate by Cyclosporine A in an Isolated Perfused Rat Liver Model

(2010) Ridhi Parasrampuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Improved Extrapolation of Hepatobiliary Clearance fromin VitroSandwich Cultured Rat Hepatocytes through Absolute Quantification of Hepatobiliary Transporters

(2010) Na Li et al.   MOLECULAR PHARMACEUTICS

Differential methotrexate hepatotoxicity on rat hepatocytes in 2-D monolayer culture and 3-D gel entrapment culture

(2009) Jian Yin et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effects of P-glycoprotein and Mrp2 inhibitors on the hepatobiliary disposition of Rhodamine 123 and its glucuronidated metabolite in isolated perfused rat livers

(2009) Ridhi Parasrampuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Serum protein binding displacement: theoretical analysis using a hypothetical radiopharmaceutical and experimental analysis with 123I-N-isopropyl-p-iodoamphetamine

(2009) Keiichi Kawai et al.   NUCLEAR MEDICINE AND BIOLOGY

Microfabricated silicon nitride membranes for hepatocyte sandwich culture

(2008) Shufang Zhang et al.   BIOMATERIALS

Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes

(2008) H. Fukuda et al.   DRUG METABOLISM AND DISPOSITION

The role of hepatic transporters in drug elimination

(2008) Christoph Funk   Expert Opinion on Drug Metabolism & Toxicology

In Vitro Biliary Clearance of Angiotensin II Receptor Blockers and 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitors in Sandwich-Cultured Rat Hepatocytes: Comparison with in Vivo Biliary Clearance

(2008) K. Abe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: Possible contribution of P-glycoprotein

(2008) Tripta Bansal et al.   LIFE SCIENCES

Role of the Murine Organic Anion-Transporting Polypeptide 1b2 (Oatp1b2) in Drug Disposition and Hepatotoxicity

(2008) R. Evers et al.   MOLECULAR PHARMACOLOGY

Functional expression of organic anion transporters in hepatic organoids reconstructed by rat small hepatocytes

(2007) Hideki Oshima et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Sex-specific extraction of organic anions by the rat liver

(2007) Penny Y.T. Wang et al.   LIFE SCIENCES