Surgical and pharmacological animal models used in drug metabolism and pharmacokinetics

Characterization of post-surgical alterations in the bile duct-cannulated rat

(2011) Dalila Bachir-Cherif et al.   XENOBIOTICA

Use of Dried Blood Spots in Drug Development: Pharmacokinetic Considerations

(2010) Malcolm Rowland et al.   AAPS Journal

Use of the Entero-Test, a Novel Approach for the Noninvasive Capture of Biliary Metabolites in Dogs

(2010) W. J. Guiney et al.   DRUG METABOLISM AND DISPOSITION

Sublingual and submandibular blood collection in mice: a comparison of effects on body weight, food consumption and tissue damage

(2010) Maike Heimann et al.   LABORATORY ANIMALS

An updated and simplified method for bile duct cannulation of rats

(2010) H Tønsberg et al.   LABORATORY ANIMALS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[11C]verapamil PET

(2009) Claudia Kuntner et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Is 1-Aminobenzotriazole an Appropriate in Vitro Tool as a Nonspecific Cytochrome P450 Inactivator?

(2008) C. D. Linder et al.   DRUG METABOLISM AND DISPOSITION

The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity

(2008) Koichi Yuki et al.   FASEB JOURNAL

Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with anN-sulfonylated dipeptide VLA-4 antagonist in rats

(2008) W. Tang et al.   XENOBIOTICA

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse

(2007) Marie Stiborová et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY