Article
Oncology
Tomoki Abe, Taro Oshikiri, Hironobu Goto, Takashi Kato, Manabu Horikawa, Ryuichiro Sawada, Hitoshi Harada, Naoki Urakawa, Hiroshi Hasegawa, Shingo Kanaji, Kimihiro Yamashita, Takeru Matsuda, Yoshihiro Kakeji
Summary: The Alb-dNLR score has been shown to be an independent prognostic factor for ESCC patients, and can predict both overall survival and cause-specific survival rates by analyzing albumin and the neutrophil-to-lymphocyte ratio.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Ji-Feng Feng, Jian-Ming Zhao, Sheng Chen, Qi-Xun Chen
Summary: The study confirmed the usefulness of NPS as an independent prognostic score in patients with resected ESCC. A nomogram based on NPS was successfully developed and validated, providing a valuable tool for individual CSS prediction in resected ESCC patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Zhiwei Zheng, Cui Yang, Chun Cai, Huide Zhu
Summary: This study revealed a correlation between high NLR and PLR with poor prognoses in esophageal squamous cell carcinoma patients, indicating that high NLR and PLR can predict disease-free survival in resectable cases.
CANCER MANAGEMENT AND RESEARCH
(2021)
Article
Multidisciplinary Sciences
Chi-Jen Chen, Ching-Tai Lee, Ying-Nan Tsai, Chao-Ming Tseng, Tzu-Haw Chen, Ming-Hung Hsu, Chih-Chun Wang, Wen-Lun Wang
Summary: Neutrophil to lymphocyte ratio (NLR) and lymphocyte to monocyte ratio (LMR) are significantly correlated with the survival rate of superficial esophageal squamous cell carcinomas (SESCC), while platelet to lymphocyte ratio (PLR) is not. A low pre-treatment LMR may be an important indicator for predicting the prognosis of SESCC.
SCIENTIFIC REPORTS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Zhaocheng Zhuang, Yanfen Li, Yihong Hong, Lin Chen, Jiawen Qian, Jing Lin, Qing Chen, Yu Qiu, Lisong Lin, Bin Shi, Lizhen Pan, Xiaoyan Zheng, Jing Wang, Fengqiong Liu, Baochang He, Fa Chen
Summary: Systemic inflammatory biomarkers AGR and NLR are independent prognostic indicators for patients with oral squamous cell carcinoma, and their combined AGR-NLR score outperforms traditional TNM staging system in predicting patient outcomes.
Article
Oncology
Moyuru Yamada, Koji Tanaka, Makoto Yamasaki, Kotaro Yamashita, Tomoki Makino, Takuro Saito, Tsuyoshi Takahashi, Yukinori Kurokawa, Masaaki Motoori, Yutaka Kimura, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Summary: Studies have shown that neoadjuvant chemotherapy followed by surgical resection improves the survival of patients with esophageal squamous cell carcinoma, and the neutrophil-to-lymphocyte ratio (NLR) may serve as a prognostic biomarker. This retrospective study analyzed the changes in NLR before and after neoadjuvant chemotherapy in 338 patients with esophageal squamous cell carcinoma. The results indicate that post-NLR was a better prognostic factor than pre-NLR for patients receiving neoadjuvant chemotherapy followed by surgical resection.
Article
Oncology
Jing-Houng Wang, Yen-Yang Chen, Kwong-Ming Kee, Chih-Chi Wang, Ming-Chao Tsai, Yuan-Hung Kuo, Chao-Hung Hung, Wei-Feng Li, Hsiang-Lan Lai, Yen-Hao Chen
Summary: Atezolizumab plus bevacizumab has been approved as the first-line treatment for unresectable hepatocellular carcinoma. This study examined the efficacy and safety of this treatment in real-world clinical practice and found that it is effective and well-tolerated. In addition, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were identified as independent prognostic factors for progression-free survival (PFS).
Article
Oncology
Ji-Feng Feng, Jian-Ming Zhao, Sheng Chen, Qi-Xun Chen
Summary: The study demonstrated that the Lung Immune Prognostic Index (LIPI) is a useful prognostic indicator in patients with resected esophageal squamous cell carcinoma (ESCC), showing a close association with cancer-specific survival (CSS) and independence in predictive ability.
CANCER MANAGEMENT AND RESEARCH
(2021)
Article
Medicine, Research & Experimental
Ji-Feng Feng, Liang Wang, Xun Yang
Summary: The study confirmed that the preoperative HALP score could be regarded as a potential independent prognostic factor for cancer-specific survival (CSS) in patients undergoing curative resection for esophageal squamous cell carcinoma (ESCC), with reliable abilities to predict CSS in any stage or gender.
BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2021)
Article
Oncology
Xianbin Wu, Runkun Han, Yanping Zhong, Nuoqing Weng, Ao Zhang
Summary: This study aimed to identify predictors of response to anti-PD-1 therapy in esophageal squamous cell carcinoma (ESCC) patients from peripheral blood parameters. The results showed that a low NLR at 6 weeks post treatment was associated with higher progression-free survival (PFS) rate in ESCC patients, but there was no significant difference in PFS rate based on NLR, PLR, MLR, or SII at baseline or 3 weeks post treatment.
CANCER CELL INTERNATIONAL
(2021)
Article
Oncology
Jiyun Park, Jun Park, Jung Hee Shin, Young-Lyun Oh, Hyun-Ae Jung, Man-Ki Chung, Jun-Ho Choe, Yong-Chan Ahn, Sun-Wook Kim, Jae-Hoon Chung, Tae-Hyuk Kim, Jae-Myoung Noh
Summary: The study found that high NLR before and after radiotherapy was associated with poor survival in patients with anaplastic thyroid cancer (ATC), indicating the importance of host immunity in ATC patients. This suggests that this finding may provide important information for designing future investigations on the impact of immune system modulating therapy in ATC.
Article
Immunology
Qian Song, Song-Xiao Xu, Jun-Zhou Wu, Lin Ling, Sheng Wang, Xin-Hua Shu, Dan-Ni Ying, Wang-Wei Pei, Yu-Chen Wu, Su-Fang Sun, Yi-Ning Zhang, Si-Hang Zhou, Zhu-Yan Shao
Summary: This study analyzed data from 991 ovarian cancer patients and found that the lymphocyte to monocyte ratio (LMR) and platelet to neutrophil ratio (PNR) were independent prognostic indicators of ovarian cancer. In contrast, the platelet to lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) had limited prognostic value. In conclusion, LMR and PNR are superior prognostic indicators in ovarian cancer.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Medicine, General & Internal
Toshihiko Mikami, Akinori Funayama, Kanae Niimi, Kenta Haga, Masami Kawaharada, Akihiko Nakamura, Wataru Katagiri, Tadaharu Kobayashi
Summary: This study investigated the predictive value of LMR, NLR, PLR, and IRB score for disease-specific survival and delayed cervical lymph node metastasis in early-stage OSCC. The findings suggest that IRB score and mode of invasion are potentially independent risk factors for delayed cervical lymph node metastasis.
Article
Endocrinology & Metabolism
Xinran Li, Lin Zhou, Yuxin Chen, Na Li, Jian Meng
Summary: This study retrospectively analyzed 71 patients with ACC and found that preoperative neutrophil-to-lymphocyte ratio (NLR) is an effective biomarker for the prognosis of ACC patients. High NLR is associated with lymph node metastasis and tumor stage, and it is correlated with overall survival but not disease-free survival in ACC patients.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Oncology
Chen Wang, Jiaqi Tong, Mengqiu Tang, Yunyun Lu, Gaofeng Liang, Zhanchun Zhang, Tian Chen
Summary: This study revealed that pretreatment NLR and PLR can serve as independent predictors for patients with locally advanced esophageal squamous cell carcinoma (ESCC) located in the middle or upper esophagus, helping to guide the choice between radical surgery or definitive chemoradiotherapy (dCRT) and being associated with prognosis. Patients with low NLR tend to have better survival outcomes when undergoing surgery.
CANCER MANAGEMENT AND RESEARCH
(2021)