Article
Oncology
H. Winters, H. J. P. Tielemans, S. Hummelink, N. J. Slater, D. J. O. Ulrich
Summary: In this study, it was found that vascularized lymph node transfer in combination with DIEP flap breast reconstruction can significantly improve lymphedema-related quality of life. Even without a decrease in volume difference, it can reduce the usage of compression garments and the need for physiotherapy.
Review
Surgery
Harm Winters, Hanneke J. P. Tielemans, Vera Paulus, Stefan Hummelink, Nicholas J. Slater, Dietmar J. O. Ulrich
Summary: Vascularized lymph node transfer (VLNT) is an effective technique for treating lymphedema in breast cancer patients. The current evidence suggests that VLNT can improve the volume differences between the arms and have a positive effect on patients' quality of life, reducing skin infections and the need for compression garment usage. The complication rate is low.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2022)
Article
Biotechnology & Applied Microbiology
Ahmet Hamdi Sakarya, Chi-Wei Huang, Chin-Yu Yang, Hui-Yi Hsiao, Frank Chun-Shin Chang, Jung-Ju Huang
Summary: The study demonstrates that vascularized lymph node transplantation (VLNT) is an effective treatment for lymphedema. VLNT reduces the volume of lymphedema by restoring lymphatic drainage function and reducing inflammation and fibrosis. It also promotes lymphangiogenesis and restores immune function locally and systemically.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2022)
Article
Medicine, General & Internal
Shinsuke Akita, Yuzuru Ikehara, Minami Arai, Hideki Tokumoto, Yoshihisa Yamaji, Kazuhiko Azuma, Yoshitaka Kubota, Hideaki Haneishi, Motoko Y. Kimura, Nobuyuki Mitsukawa
Summary: The study investigated the effects of partial blood flow impairment in lymph node flaps on the therapeutic results of vascularized lymph node transfer (VLNT) for lymphedema. Clinical and histological examinations showed significant differences in volume reduction and lymph flow recanalization rate between good and poor postoperative blood flow groups. Thrombi formation and immunocompetent cell aggregation were observed in congested lymph nodes in mouse models. Maintaining blood flow in transferred lymph nodes is crucial for the success of VLNT.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Kyung-Chul Moon, Hyung-Kyu Kim, Tae-Yul Lee, Hi-Jin You, Deok-Woo Kim
Summary: The study aims to compare clinical outcomes of vascularized lymph node transfer (VLNT) in treating lymphedema in upper and lower extremities. Results show that VLNT can effectively treat patients with advanced-stage lymphedema, with better outcomes observed in upper extremity patients compared to lower extremity patients.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2022)
Article
Chemistry, Analytical
Chang-Cheng Chang, Wei-Ling Jan, Cheng-Huei Juan, Nai-Hsin Meng, Bor-Shyh Lin, Hung-Chi Chen
Summary: An innovative wireless device for bioimpedance analysis was developed for evaluating post-dual-site free vascularized lymph node transfer (VLNT). The device showed a significant increase in bioimpedance on the affected limbs postoperatively, especially in the distal limb, and these alterations were significantly correlated with follow-up time. This device has the potential for real-time monitoring of interstitial fluid alterations after surgery.
Review
Biology
Farrah C. Liu, Kometh Thawanyarat, Yelissa Navarro, Dung H. Nguyen
Summary: The use of the omental flap in breast reconstruction has gained research popularity in recent decades. Compared to traditional donor flap reconstruction, current literature shows the benefits of using the omentum in autologous breast reconstruction. This technique offers a viable option for patients who do not meet the criteria for traditional autologous reconstruction techniques, allowing for more natural breast restoration without the complications of donor-site mortality.
Article
Oncology
Gonzalo Mallarino-Restrepo, Miffy C. Y. Lin, Ming-Huei Cheng
Summary: This study investigated the outcomes of distal facial vein catheterization (DFVC) for venous thrombosis management in vascularized submental lymph nodes (VSLN) flap transplantations. The study found that DFVC significantly reduced the risk of late venous thrombosis.
JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
David Cibula, Martina Borcinova, Simone Marnitz, Jiri Jarkovsky, Jaroslav Klat, Radovan Pilka, Aureli Torne, Ignacio Zapardiel, Almerinda Petiz, Laura Lay, Borek Sehnal, Jordi Ponce, Michal Felsinger, Octavio Arencibia-Sanchez, Peter Kascak, Kamil Zalewski, Jiri Presl, Alicia Palop-Moscardo, Solveig Tingulstad, Ignace Vergote, Mikulas Redecha, Filip Fruhauf, Christhardt Koehler, Roman Kocian
Summary: The study found that replacing standard PLND with bilateral SLN biopsy in cervical cancer surgical treatment does not eliminate the risk of mild to moderate LLL, which develops regardless of the number of SLNs removed.
Review
Surgery
Krystof Stanek, Filip Jonas, Pavla Ticha, Martin Molitor, Ondrej Mestak
Summary: This review evaluated animal models of vascularized lymph node transfer (VLNT) and compared their advantages and disadvantages. The study found that rats were the most commonly used animal model, and the main areas of research focused on lymphedema, ischemia, and lymphatic pathway reestablishment.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Surgery
Justin M. Broyles, Jeffrey M. Smith, Franklin C. Wong, Matthew M. Hanasono, Edward Chang, S. Cheenu Kappadath, Mark Schaverien
Summary: This study demonstrates the utility of SPECT/CT lymphoscintigraphy in presurgical planning for groin vascularized lymph node transplantation. It also evaluates the physiological lymphatic drainage to the superficial inguinal lymph nodes.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Surgery
Stav Brown, Babak J. Mehrara, Michelle Coriddi, Leslie McGrath, Michele Cavalli, Joseph H. Dayan
Summary: The purpose of this study was to evaluate the safety and efficacy of vascularized lymph node transplant (VLNT) using all available outcome measures. The results showed that VLNT significantly improved various indicators of lymphedema, with low complication rates. Using omentum as the donor site had a lower risk of lymphedema.
Editorial Material
Surgery
Giorgio De Santis, Bharat Saxena, Marta Starnoni, Marco Pappalardo, Vinay Jacob
Summary: The study suggests that a combination of antibiotics, decongestive therapy, and vascularized submental lymph node transfer can effectively improve early-stage lower limb filarial lymphedema.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Surgery
Mark V. Schaverien, Wayne L. Hofstetter, Melissa S. Hall, Dawn N. Chen, Jesse C. Selber
Summary: Jejunal mesenteric vascularized lymph node transplantation is an effective surgical treatment for upper extremity lymphedema, resulting in reduced limb volume and extracellular fluid, and improved patient-reported limb function and outcomes measures compared with optimized conservative therapy alone.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Review
Surgery
Julia Roka-Palkovits, Miffy Chia-Yu Lin, Chieh-Han J. Tzou, Ines Tinhofer, Ming-Huei Cheng
Summary: Vascularized lymph node transfer with retrograde manual lymphatic drainage significantly improves the treatment outcomes for extremity lymphedema patients, with better results observed in distal recipient sites.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
