Article
Surgery
Jin Wang, Wen Lv, Shihai Xu, Chao Yang, Bo Du, Yuanbo Zhong, Fei Shi, Aijun Shan
Summary: Intraoperative incision irrigation with high-volume normal saline is effective in reducing the rate of surgical site infection for patients with abdominal infections. This intervention is associated with lower rates of superficial and deep surgical site infections, as well as lower rates of incision seroma, shorter duration of antibiotics use, and unplanned readmission.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Wei Hsiung, Yu-Cheng Yao, Hsi-Hsien Lin, Shih-Tien Wang, Lei Hsiung, Kuan-Jung Chen, Ming-Chau Chang, Po-Hsin Chou
Summary: This study investigates the risk factors and optimal amount of intraoperative irrigation for preventing postoperative surgical site infection (SSI) following lumbar spine surgery. The results suggest that insufficient irrigation volume and diabetes are both risk factors for postoperative SSI. In order to reduce the risk of SSI, it is recommended to use more than 1400 mL/h of normal saline for intraoperative wound irrigation.
Article
Dermatology
Chunmei Fu, Linghong Meng, Miguo Ma, Na Li, Jingcen Zhang
Summary: The meta-analysis found that both antibiotic irrigation and aqueous povidone-iodine irrigation significantly reduced the risk of surgical site infections compared to saline irrigation or no irrigation. Further research is needed to validate these findings.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Agronomy
Mohamed E. A. El-sayed, Mohamed Hazman, Ayman Gamal Abd El-Rady, Lal Almas, Mike McFarland, Ali Shams El Din, Steve Burian
Summary: The study evaluated the use of saline groundwater and soil amendments to enhance wheat production efficiency in Egypt. Results showed that biochar addition increased grain yield while saline water reduced it, indicating that biochar could alleviate salinity stress.
Article
Surgery
Kazuyuki Gyoten, Hiroyuki Kato, Aoi Hayasaki, Takehiro Fujii, Yusuke Iizawa, Yasuhiro Murata, Akihiro Tanemura, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Masanobu Usui, Hiroyuki Sakurai, Shuji Isaji
Summary: Gastric Candida colonization is highly associated with SSIs after high-level HBP surgeries, independent of immunocompromised status.
LANGENBECKS ARCHIVES OF SURGERY
(2021)
Review
Nursing
Junru Gao, Yunyun Wang, Jingyu Song, Ze Li, Jianan Ren, Peige Wang
Summary: Negative pressure wound therapy significantly improves wound healing rate, healing time, healing area, hospital stay, and adverse events for surgical site infection patients. However, it is also associated with increased medical costs. Further high-quality randomized controlled trials are needed to optimize the application of negative pressure wound therapy.
JOURNAL OF ADVANCED NURSING
(2021)
Article
Agronomy
Wenjia Li, Yanming Gao, Yongqiang Tian, Jianshe Li
Summary: This study investigated the effects of double-root-grafting on tomato growth, yields, quality, and root-zone properties under alternate partial root-zone irrigation. The results showed that, under these conditions, double-root-grafting increased fruit yields and reduced salt damage to the plants.
AGRICULTURAL WATER MANAGEMENT
(2022)
Article
Gastroenterology & Hepatology
Tommaso Pollini, Paul Wong, Lyonell B. B. Kone, Rym El Khoury, Chris Kabir, Vijay K. K. Maker, Mihaela Banulescu, Ajay V. V. Maker
Summary: This study aimed to determine the association between post-pancreatectomy drain placement and timing of drain removal with infectious outcomes. The findings showed that drain placement was associated with increased risk of organ/space infection after distal pancreatectomy. The timing of drain removal also had an impact on the occurrence of infection.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Public, Environmental & Occupational Health
T. Zhang, X. Lian, Y. Chen, B. Cai, J. Xu
Summary: This study analyzed the incidence and characteristics of postoperative surgical site infection (SSI) after posterior thor-acolumbar and lumbar instrumentation. The results showed an average SSI rate of 1.8%. Most patients with deep wound SSI can be successfully treated with retention of implants, but early diagnosis, positive revision surgery, strict irrigation, thorough debridement, and long-term antibiotic treatment are crucial.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Oncology
Yuki Imaoka, Masahiro Ohira, Koki Sato, Kouki Imaoka, Tomoaki Bekki, Ryosuke Nakano, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan
Summary: This study aimed to investigate the relationship between abdominal aortic calcification (AAC) and the severity of postoperative complications after major hepatobiliary pancreatic (HBP) surgery. The results showed that higher AAC was associated with increased incidence rates of surgical site infections and a higher Comprehensive Complication Index (CCI). Therefore, careful anastomosis and infection control are necessary to prevent the progression of severe postoperative complications among patients with high AAC.
ANTICANCER RESEARCH
(2022)
Article
Hematology
Koki Maeda, Hideo Wada, Toru Shinkai, Akihiro Tanemura, Takeshi Matsumoto, Shugo Mizuno
Summary: The study found that APTT-CWA plays an important role in predicting bleeding risk after major hepatobiliary pancreatic surgery, with the highest incidence of massive bleeding in patients undergoing hepatectomy. Detailed changes in the hemostatic system can be detected using APTT-CWA.
THROMBOSIS RESEARCH
(2021)
Article
Surgery
Alexsander K. Bressan, Susan Isherwood, Oliver F. Bathe, Elijah Dixon, Francis R. Sutherland, Chad G. Ball
Summary: This study demonstrates that a single preoperative dose of methylprednisolone significantly reduces the length of hospital stay, postoperative serum bilirubin, and PT-INR levels, as well as infectious and overall complications following major hepatectomy.
Article
Dermatology
Biao Dong, Jing Chen, Mina Song, Changjiang You, Changjiang Lei, Ying Fan
Summary: A meta-analysis was conducted to evaluate risk factors for surgical site wound infections (SSWIs) in hepatic and pancreatic tumour resection (HPTR). A total of 2349 interrelated investigations were reviewed, and 9 investigations with 22,774 individuals were included. The results showed that HT patients with biliary reconstruction had significantly higher SSWI risk, while there was no significant difference in SSWI between PT individuals who underwent different types of surgeries. However, caution should be exercised due to the limited number of selected investigations for this meta-analysis.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Orthopedics
Jianqiang Du, Wenxiu Qin, Yanjun Zhang, Zhengyuan Yang, Junjie Li, Jun Yang, Qiang Deng
Summary: In spinal tuberculosis surgery, topical administration of drugs to the lesion is a preventive treatment measure. This study compared the use of streptomycin flush and no flush in the treatment of spinal tuberculosis and found that streptomycin flush helped control postoperative infections and reduced the duration of antibiotic use and hospital stay.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Surgery
Ryo Maemoto, Hiroshi Noda, Kosuke Ichida, Yasuyuki Miyakura, Nao Kakizawa, Erika Machida, Hidetoshi Aizawa, Takaharu Kato, Masahiro Iseki, Taro Fukui, Yuta Muto, Shota Fukai, Shingo Tsujinaka, Yuuri Hatsuzawa, Fumiaki Watanabe, Masakazu Nagamori, Jun Takahashi, Yasuaki Kimura, Shimpei Maeda, Noriya Takayama, Ryotaro Sakio, Rei Takahashi, Tsutomu Takenami, Natsumi Matsuzawa, Makiko Mieno, Toshiki Rikiyama
Summary: This trial evaluated the superiority of intraoperative wound irrigation with povidone-iodine compared with saline for reducing surgical site infection. The results showed that the irrigation with povidone-iodine did not significantly reduce the incidence of incisional SSI, suggesting a need for reconsideration of the current recommendation.
Editorial Material
Surgery
Su Kah Goh, Daniel R. A. Cox, Andrew Weickhardt, Vijayaragavan Muralidharan, Marcos Perini
ANZ JOURNAL OF SURGERY
(2022)
Article
Gastroenterology & Hepatology
Jess Howell, Avik Majumdar, Michael A. Fink, Mandy Byrne, Geoff McCaughan, Simone Strasser, Michael Crawford, Peter Hodgkinson, Katherine A. Stuart, Caroline Tallis, John Chen, Alan Wigg, Robert Jones, Bryon Jaques, Gary Jeffrey, Leon Adams, Michael C. Wallace, Stephen Munn, Ed Gane, Alex J. Thompson, Paul Gow
Summary: Since the introduction of universal access to DAAs in 2016 in Australia and New Zealand, the number and proportion of liver transplantations performed for HCV-related liver cirrhosis and HCC have decreased. This was also associated with a 31% reduction in death after liver transplantation.
LIVER TRANSPLANTATION
(2022)
Review
Gastroenterology & Hepatology
Ruelan Furtado, Osamu Yoshino, Vijayaragavan Muralidharan, Marcos Perini, Stephen J. Wigmore
Summary: Hepatectomy after bile duct injury is a rare but important procedure for the management of vasculo-biliary injury. It can effectively alleviate symptoms in the majority of cases, although postoperative bile leaks and intra-abdominal infection are common.
Article
Oncology
P. J. Ross, H. S. Wasan, D. Croagh, M. Nikfarjam, N. Nguyen, M. Aghmesheh, A. M. Nagrial, D. Bartholomeusz, A. Hendlisz, T. Ajithkumar, C. Iwuji, N. E. Wilson, D. M. Turner, D. C. James, E. Young, M. T. Harris
Summary: This study suggests that combining P-32 microparticles with standard-of-care chemotherapy may have clinically relevant benefits for patients with unresectable locally advanced pancreatic cancer. The treatment has an acceptable safety profile and results in improved local disease control and overall survival.
Article
Anesthesiology
Laurence Weinberg, Fumitaka Yanase, Shervin Tosif, Bernhard Riedel, Rinaldo Bellomo, Robert G. Hahn
Summary: This study found that there are different temporal patterns of plasma syndecan-1 concentration after surgery, with the greatest increases observed in patients with greater blood loss, more liver surgery, and longer operations.
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2023)
Editorial Material
Surgery
Wendall Zhang, Laurence Weinberg, Khashayar Asadi, Mehrdad Nikfarjam
ANZ JOURNAL OF SURGERY
(2023)
Article
Anesthesiology
Jessica F. Davies, Ljubiana Trajceska, Laurence Weinberg
Summary: Anaesthetic agents have financial and environmental impacts, and this study aimed to quantify the impacts of different agents used in surgery at an Australian university teaching hospital. The volume of different agents purchased between 2010 and 2020 was analyzed in terms of financial and environmental impact. Replacing the most environmentally damaging and expensive agent with alternatives could have significant financial and environmental benefits. For example, replacing desflurane with low flow sevoflurane could save greenhouse gas emissions equivalent to driving over 1.4 million kilometers in an average petrol car.
ANAESTHESIA AND INTENSIVE CARE
(2023)
Article
Multidisciplinary Sciences
Vichaya Champreeda, Raymond Hu, Brandon Chan, Owen Tomasek, Yuan-Hong Lin, Laurence Weinberg, Will Howard, Chong O. Tan
Summary: This prospective observational study aimed to establish the frequency of postoperative nocturnal respiratory abnormalities among patients undergoing major surgery who received ward-level care. The study found that prolonged apnea events and other physiological abnormalities were frequently detected on the first postoperative night, but these abnormalities were not associated with postoperative pulmonary complications (PPCs). Future research should investigate the significance of these detected aberrations.
Article
Anesthesiology
Caitlin S. R. Low, Sean Z. Ngui, Matthew J. Casey, Chloe Vuong, Afsana Afroz, Shomik Sengupta, Laurence Weinberg
Summary: The study aimed to investigate the pass rate and comfort of wearing four commonly used filtering facepiece respirators in Australian healthcare providers. The results showed differences in pass rate and ease of donning, doffing, and comfort among the respirators. Therefore, it is important for healthcare facilities to consider these factors when designing a respiratory protection program.
ANAESTHESIA AND INTENSIVE CARE
(2023)
Article
Multidisciplinary Sciences
Laurence Weinberg, Sarah Aishah Azlina Aitken, Peter Kaldas, Luke Fletcher, Patryck Lloyd-Donald, Peter Le, Daniel Do, Carla Borg Caruana, Dominic Walpole, Joseph Ischia, Ronald Ma, Chong Oon Tan, Dong-Kyu Lee
Summary: This study aims to evaluate the relationship between postoperative complications and hospital costs, as well as the relationship between postoperative complications and mortality following radical cystectomy. The study found that postoperative complications were significantly associated with increased hospital costs and mortality.
Review
Gastroenterology & Hepatology
Daniel R. A. Cox, William Chung, Josephine Grace, Darren Wong, Numan Kutaiba, Dinesh Ranatunga, Richard Khor, Marcos Perini, Michael Fink, Robert Jones, Mark Goodwin, Alex Dobrovic, Adam Testro, Vijayaragavan Muralidharan
Summary: Hepatocellular carcinoma (HCC) is a highly aggressive primary liver cancer and the third leading cause of cancer-related death worldwide. Recent years have witnessed an increasing number of treatment options for HCC, including both curative and non-curative therapies. However, these advancements have also posed challenges in disease monitoring, particularly in the early detection of HCC recurrence. This review will discuss and evaluate the current serological and radiological strategies for post-treatment monitoring and prognostication, as well as their limitations.
Article
Genetics & Heredity
Daniel R. A. Cox, Tess McClure, Fan Zhang, Boris Ka Leong Wong, Adam Testro, Su Kah Goh, Vijayaragavan Muralidharan, Alexander Dobrovic
Summary: Both graft-specific DNA methylation analysis and donor-recipient genotyping techniques successfully quantified gdcfDNA in patients post-liver transplantation, with significant correlation. While the two techniques performed similarly, gdcfDNA monitoring based on graft-specific DNA methylation patterns in cfDNA offers greater practical advantages and enhances the potential for clinical translation.
Article
Anesthesiology
Tim G. Coulson, Lachlan F. Miles, Alex Zarbock, Louise M. Burrell, Sheila K. Patel, Thilo von Groote, David Pilcher, Laurence Weinberg, Giovanni Landoni, Rinaldo Bellomo
Summary: Compared with norepinephrine, angiotensin II infusion can suppress renin release while maintaining aldosterone levels, providing a potential treatment for vasoplegia after cardiac surgery. Plasma renin concentration before surgery is associated with vasopressor requirement for norepinephrine but not angiotensin II.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Multidisciplinary Sciences
Vidhura Ratnasekara, Laurence Weinberg, Samuel Anthony Johnston, Luke Fletcher, Patrick Nugraha, Daniel Robert Anthony Cox, Raymond Hu, Ilonka Meyer, Osamu Yoshino, Marcos Vinius Perini, Vijayaragavan Muralidharan, Mehrdad Nikfarjam, Dong-Kyu Lee
Summary: In a retrospective study of patients undergoing complex hepato-pancreato-biliary (HPB) surgery, the use of a multimodal intrathecal analgesia (MITA) technique combining intrathecal morphine, clonidine, and bupivacaine was found to result in reduced postoperative opioid use and better analgesia compared to the use of intrathecal morphine alone. However, patients in the MITA group had a higher incidence of postoperative hypotension requiring vasopressor support.
Review
Medicine, General & Internal
Jarryd Ludski, Bradly Carp, Tim Makar, Michael Yii, Dong-Kyu Lee, Laurence Weinberg
Summary: By 2030, the global population of nonagenarians is expected to exceed 30 million, leading to a potential increase in nonagenarians undergoing cardiac surgery. This scoping review aims to identify knowledge gaps and improve understanding of nonagenarians undergoing cardiac surgery.
