Immunopathogenesis of chronic hepatitis B

The modification of Tapasin enhances cytotoxic T lymphocyte activity of intracellularly delivered CTL epitopes via cytoplasmic transduction peptide

(2013) X. Chen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Identification of α-taxilin as an essential factor for the life cycle of hepatitis B virus

(2013) Jasmin Hoffmann et al.   JOURNAL OF HEPATOLOGY

MicroRNA-146a Feedback Suppresses T Cell Immune Function by Targeting Stat1 in Patients with Chronic Hepatitis B

(2013) S. Wang et al.   JOURNAL OF IMMUNOLOGY

High level of IL-27 positively correlated with Th17 cells may indicate liver injury in patients infected with HBV

(2013) Geng-Lin Zhang et al.   LIVER INTERNATIONAL

A Clinical Study of HBsAg-Activated Dendritic Cells and Cytokine-Induced Killer Cells During the Treatment for Chronic Hepatitis B

(2013) Y.-J. Ma et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

HBcAg-Specific IL-21-Producing CD4+ T Cells are Associated with Relative Viral Control in Patients with Chronic Hepatitis B

(2013) L. Li et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice

(2013) Pascale Buchmann et al.   VACCINE

HBV endemicity in Mexico is associated with HBV genotypes H and G

(2013) Sonia Roman   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ

(2012) Jieliang Chen et al.   HEPATOLOGY

Downregulation of TLR7/9 leads to deficient production of IFN-α from plasmacytoid dendritic cells in chronic hepatitis B

(2012) Ning Xu et al.   INFLAMMATION RESEARCH

Maternal and perinatal outcome in cases of fulminant viral hepatitis in late pregnancy

(2012) Liuzhi Deng et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Imbalance of interleukin-17-producing CD4 T cells/regulatory T cells axis occurs in remission stage of patients with hepatitis B virus-related acute-on-chronic liver failure

(2012) Geng-Lin Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Structures of Hepatitis B Virus Cores Presenting a Model Epitope and Their Complexes with Antibodies

(2012) A.M. Roseman et al.   JOURNAL OF MOLECULAR BIOLOGY

Viral Quasispecies Evolution

(2012) E. Domingo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Hepatitis B Viral DNA Decline at Loss of HBeAg Is Mainly Explained by Reduced cccDNA Load – Down-Regulated Transcription of PgRNA Has Limited Impact

(2012) Sebastian Malmström et al.   PLoS One

Regulatory T cells are the most important determinant factor of hepatitis B infection prognosis: A systematic review and meta-analysis

(2012) Seyed Hossein Aalaei-Andabili et al.   VACCINE

T cell immunopathogenesis and immunotherapeutic strategies for chronic hepatitis B virus infection

(2012) Yukihiro Shimizu   WORLD JOURNAL OF GASTROENTEROLOGY

The role of the PD-1 pathway in autoimmunity and peripheral tolerance

(2011) Brian T. Fife et al.   Annals of the New York Academy of Sciences

Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma

(2011) Danny Ka Ho Wong et al.   HEPATOLOGY

Hepatitis B virus drug resistance to current nucleos(t)ide analogs: Mechanisms and mutation sites

(2011) Lihui Deng et al.   HEPATOLOGY RESEARCH

HCV core and NS3 proteins manipulate human blood-derived dendritic cell development and promote Th 17 differentiation

(2011) Zhengkun Tu et al.   INTERNATIONAL IMMUNOLOGY

Immunopathogenesis and prognostic immune markers of chronic hepatitis B virus infection

(2011) Zheng Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Role of stress-induced NKG2D ligands in liver diseases

(2011) Alisan Kahraman et al.   LIVER INTERNATIONAL

Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

(2011) P. A. Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An overview of occult hepatitis B virus infection

(2011) Zeinab Nabil Ahmed Said   WORLD JOURNAL OF GASTROENTEROLOGY

The natural history of chronic HBV infection and geographical differences

(2010) Yun-Fan Liaw et al.   ANTIVIRAL THERAPY

Skewed ratios between CD3 + T cells and monocytes are associated with poor prognosis in patients with HBV-related acute-on-chronic liver failure

(2010) Feng Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Down-regulation of Z39Ig on macrophages by IFN-γ in patients with chronic HBV infection

(2010) Sheng Guo et al.   CLINICAL IMMUNOLOGY

Carriers of Inactive Hepatitis B Virus Are Still at Risk for Hepatocellular Carcinoma and Liver-Related Death

(2010) Jin–De Chen et al.   GASTROENTEROLOGY

Hepatitis B: The virus and disease

(2010) T. Jake Liang   HEPATOLOGY

Intrahepatic levels of PD-1/PD-L correlate with liver inflammation in chronic hepatitis B

(2010) Ji Chen et al.   INFLAMMATION RESEARCH

Hepatitis B immunoglobulin injection in pregnancy to interrupt hepatitis B virus mother-to-child transmission—a meta-analysis

(2010) Zhongjie Shi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Hepatitis B e-antigen Persistency is Associated with the Properties of HBV-Specific CD8 T Cells in CHB Patients

(2010) Guoping Peng et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B

(2010) Eric T.T.L. Tjwa et al.   JOURNAL OF HEPATOLOGY

HBx-Induced Hepatic Steatosis and Apoptosis Are Regulated by TNFR1- and NF-κB-Dependent Pathways

(2010) Ji Yeon Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulatory T cells in chronic hepatitis B patients affect the immunopathogenesis of hepatocellular carcinoma by suppressing the anti-tumour immune responses

(2010) H. H. Zhang et al.   JOURNAL OF VIRAL HEPATITIS

Lamivudine in Late Pregnancy to Interrupt In Utero Transmission of Hepatitis B Virus

(2010) Zhongjie Shi et al.   OBSTETRICS AND GYNECOLOGY

Viral hepatocarcinogenesis

(2010) W-L Tsai et al.   ONCOGENE

B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure

(2010) P. Farci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating CD4+CD25high Regulatory T Cells and Expression of PD-1 and BTLA on CD4+ T Cells in Patients with Chronic Hepatitis B Virus Infection

(2010) Xue-Ping Nan et al.   VIRAL IMMUNOLOGY

Impaired TLR3/IFN-β signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: Relevance to the severity of liver damage

(2009) Ning Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interleukin-17-producing CD4+ T cells increase with severity of liver damage in patients with chronic hepatitis B

(2009) Ji-Yuan Zhang et al.   HEPATOLOGY

Control of cccDNA function in hepatitis B virus infection

(2009) Massimo Levrero et al.   JOURNAL OF HEPATOLOGY

Altered serumN-glycomics in chronic hepatitis B patients

(2009) Hong-lian Gui et al.   LIVER INTERNATIONAL

Independent and Additive Interactive Effects Among Tumor Necrosis Factor-α Polymorphisms, Substance Use Habits, and Chronic Hepatitis B and Hepatitis C Virus Infection on Risk for Hepatocellular Carcinoma

(2009) Jen-Eing Jeng et al.   MEDICINE

HBsAg inhibits TLR9-mediated activation and IFN-α production in plasmacytoid dendritic cells

(2009) Yongfen Xu et al.   MOLECULAR IMMUNOLOGY

Microanatomy of the liver immune system

(2009) Eszter Nemeth et al.   Seminars in Immunopathology

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients

(2008) Jeroen N. Stoop et al.   CLINICAL IMMUNOLOGY

The Characteristics of the Cell-Mediated Immune Response Identify Different Profiles of Occult Hepatitis B Virus Infection

(2008) Alessandro Zerbini et al.   GASTROENTEROLOGY

New concepts in the immunopathogenesis of chronic hepatitis B: the importance of the innate immune response

(2008) Dilip Ratnam et al.   Hepatology International

Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus

(2008) Marjoleine L. Op den Brouw et al.   IMMUNOLOGY

Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection

(2008) A. Ross Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection

(2008) Abhishek Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Severe dendritic cell perturbation is actively involved in the pathogenesis of acute-on-chronic hepatitis B liver failure

(2008) Zheng Zhang et al.   JOURNAL OF HEPATOLOGY

A Mechanism To Explain the Selection of the Hepatitis e Antigen-Negative Mutant during Chronic Hepatitis B Virus Infection

(2008) L. Frelin et al.   JOURNAL OF VIROLOGY

Host Ethnicity and Virus Genotype Shape the Hepatitis B Virus-Specific T-Cell Repertoire

(2008) A. T. Tan et al.   JOURNAL OF VIROLOGY

Regulatory T cells and the induction of IL-17

(2008) A Kitani et al.   Mucosal Immunology

Th1 Disabled Function in Response to TLR4 Stimulation of Monocyte-Derived DC from Patients Chronically-Infected by Hepatitis C Virus

(2008) Laure Perrin-Cocon et al.   PLoS One

Effect of viral load on T-lymphocyte failure in patients with chronic hepatitis B

(2008) Jing You et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Circulating CD4+ CD25+regulatory T cells correlate with chronic hepatitis B infection

(2007) Guoping Peng et al.   IMMUNOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY