Modulation of immunity and inflammatory gene expression in the gut, in inflammatory diseases of the gut and in the liver by probiotics

Sources, isolation, characterisation and evaluation of probiotics

(2013) Luis Fontana et al.   BRITISH JOURNAL OF NUTRITION

Effect of the combined probiotics with aflatoxin B1-degrading enzyme on aflatoxin detoxification, broiler production performance and hepatic enzyme gene expression

(2013) Rui-yu Zuo et al.   FOOD AND CHEMICAL TOXICOLOGY

Saccharomyces boulardiiandBacillus subtilisB10 Modulate TLRs Mediated Signaling to Induce Immunity by Chicken BMDCs

(2013) Imran Rashid Rajput et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Symbiotic formulation in experimentally induced liver fibrosis in rats: intestinal microbiota as a key point to treat liver damage?

(2013) Giuseppe D'Argenio et al.   LIVER INTERNATIONAL

Lactobacillus caseiZhang modulate cytokine and Toll-like receptor expression and beneficially regulate poly I:C-induced immune responses in RAW264.7 macrophages

(2013) Yuzhen Wang et al.   MICROBIOLOGY AND IMMUNOLOGY

Cell-Free Culture Supernatant of Bifidobacterium breve CNCM I-4035 Decreases Pro-Inflammatory Cytokines in Human Dendritic Cells Challenged with Salmonella typhi through TLR Activation

(2013) Miriam Bermudez-Brito et al.   PLoS One

Immunoregulatory Effect of Bifidobacteria Strains in Porcine Intestinal Epithelial Cells through Modulation of Ubiquitin-Editing Enzyme A20 Expression

(2013) Yohsuke Tomosada et al.   PLoS One

Probiotic Yeast Inhibits VEGFR Signaling and Angiogenesis in Intestinal Inflammation

(2013) Xinhua Chen et al.   PLoS One

Probiotics VSL#3 Protect against Development of Visceral Pain in Murine Model of Irritable Bowel Syndrome

(2013) Eleonora Distrutti et al.   PLoS One

Probiotic Mechanisms of Action

(2012) Miriam Bermudez-Brito et al.   ANNALS OF NUTRITION AND METABOLISM

Influence of Exposure Time on Gene Expression by Human Intestinal Epithelial Cells Exposed to Lactobacillus acidophilus

(2012) Sarah O'Flaherty et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Early administration of probioticLactobacillus acidophilusand/or prebiotic inulin attenuates pathogen-mediated intestinal inflammation and Smad 7 cell signaling

(2012) Ondulla T. Foye et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

(2012) Katerina Tsilingiri et al.   GUT

Metabolites of Lactobacillus plantarum 2142 Prevent Oxidative Stress-Induced Overexpression of Proinflammatory Cytokines in IPEC-J2 Cell Line

(2012) Erzsebet Paszti-Gere et al.   INFLAMMATION

Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-18

(2012) Akemi Kosaka et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effect of Bifidobacterium bifidum BF-1 on gastric protection and mucin production in an acute gastric injury rat model

(2012) A. Gomi et al.   JOURNAL OF DAIRY SCIENCE

Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system

(2012) Darab Ghadimi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lactobacillus rhamnosus GG and Bifidobacterium animalis MB5 Induce Intestinal but Not Systemic Antigen-Specific Hyporesponsiveness in Ovalbumin-Immunized Rats

(2012) Alberto Finamore et al.   JOURNAL OF NUTRITION

Effects of Bifidobacterium breve on inflammatory gene expression in neonatal and weaning rat intestine

(2012) Yoshikazu Ohtsuka et al.   PEDIATRIC RESEARCH

Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria

(2012) Josep Bassaganya-Riera et al.   PLoS One

Human Intestinal Dendritic Cells Decrease Cytokine Release against Salmonella Infection in the Presence of Lactobacillus paracasei upon TLR Activation

(2012) Miriam Bermudez-Brito et al.   PLoS One

Lactobacillus rhamnosus (LGG) Regulates IL-10 Signaling in the Developing Murine Colon through Upregulation of the IL-10R2 Receptor Subunit

(2012) Julie Mirpuri et al.   PLoS One

Anti-Inflammatory Lactobacillus rhamnosus CNCM I-3690 Strain Protects against Oxidative Stress and Increases Lifespan in Caenorhabditis elegans

(2012) Gianfranco Grompone et al.   PLoS One

Co-administration of Bacillus subtilis RJGP16 and Lactobacillus salivarius B1 strongly enhances the intestinal mucosal immunity of piglets

(2012) Jun Deng et al.   RESEARCH IN VETERINARY SCIENCE

Regulation of TLR4, p38 MAPkinase, IκB and miRNAs by inactivated strains of lactobacilli in human dendritic cells

(2012) L. Giahi et al.   Beneficial Microbes

Transcriptomic response of immune signalling pathways in intestinal epithelial cells exposed to lipopolysaccharides, Gram-negative bacteria or potentially probiotic microbes

(2012) J. Audy et al.   Beneficial Microbes

Interaction Between Obesity and the Gut Microbiota: Relevance in Nutrition

(2011) Nathalie M. Delzenne et al.   Annual Review of Nutrition

The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice

(2011) Natividad Garrido-Mesa et al.   BIOCHEMICAL PHARMACOLOGY

Lactobacillus rhamnosus GG and Streptococcus thermophilus induce suppressor of cytokine signalling 3 (SOCS3) gene expression directly and indirectly via interleukin-10 in human primary macrophages

(2011) S. Latvala et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Probiotic genomic DNA reduces the production of pro-inflammatory cytokine tumor necrosis factor-alpha

(2011) Chung Hee Kim et al.   FEMS MICROBIOLOGY LETTERS

Expression of immune-related genes in rainbow trout (Oncorhynchus mykiss) induced by probiotic bacteria during Lactococcus garvieae infection

(2011) Tania Pérez-Sánchez et al.   FISH & SHELLFISH IMMUNOLOGY

Gene Expression Profiling Identifies Mechanisms of Protection to Recurrent Trinitrobenzene Sulfonic Acid Colitis Mediated by Probiotics

(2011) Rob Mariman et al.   INFLAMMATORY BOWEL DISEASES

Role of Natural Killer and Dendritic Cell Crosstalk in Immunomodulation by Commensal Bacteria Probiotics

(2011) Valeria Rizzello et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

An evaluation of the effects of Lactobacillus ingluviei on body weight, the intestinal microbiome and metabolism in mice

(2011) Emmanouil Angelakis et al.   MICROBIAL PATHOGENESIS

Clostridium butyricum activates TLR2-mediated MyD88-independent signaling pathway in HT-29 cells

(2011) Quanxin Gao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anti-inflammatory and immunomodulatory efficacy of indigenous probiotic Lactobacillus plantarum Lp91 in colitis mouse model

(2011) Raj Kumar Duary et al.   MOLECULAR BIOLOGY REPORTS

Dose-Dependent Immunomodulation of Human Dendritic Cells by the Probiotic Lactobacillus rhamnosus Lcr35

(2011) Bertrand Evrard et al.   PLoS One

Saccharomyces cerevisiae Modulates Immune Gene Expressions and Inhibits ETEC-Mediated ERK1/2 and p38 Signaling Pathways in Intestinal Epithelial Cells

(2011) Galliano Zanello et al.   PLoS One

Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production

(2011) Mitsuharu Matsumoto et al.   PLoS One

Modulation of intestinal morphology and immunity in nile tilapia (Oreochromis niloticus) by Lactobacillus rhamnosus GG

(2011) N. Pirarat et al.   RESEARCH IN VETERINARY SCIENCE

ProbioticLactobacillus rhamnosusdownregulatesFCER1andHRH4expression in human mast cells

(2011) Anna Oksaharju   WORLD JOURNAL OF GASTROENTEROLOGY

Bifidobacterium breve – HT-29 cell line interaction: modulation of TNF-α induced gene expression

(2011) R. Boesten et al.   Beneficial Microbes

Probiotics

(2010) N. T. Williams   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Inulin and probiotics in newly weaned piglets: effects on intestinal morphology, mRNA expression levels of inflammatory marker genes and haematology

(2010) Christiane Mair et al.   ARCHIVES OF ANIMAL NUTRITION

Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation

(2010) Rachel C Anderson et al.   BMC MICROBIOLOGY

Impact of lipoteichoic acid modification on the performance of the probiotic Lactobacillus rhamnosus GG in experimental colitis

(2010) I. J. J. Claes et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Lactobacillus acidophilus induces virus immune defence genes in murine dendritic cells by a Toll-like receptor-2-dependent mechanism

(2010) Gudrun Weiss et al.   IMMUNOLOGY

In vitro screening of probiotics and synbiotics according to anti-inflammatory and anti-proliferative effects

(2010) Julien Grimoud et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Novel Evidence for Chronic Exposure to Endotoxin in Human Nonalcoholic Steatohepatitis

(2010) Froukje J. Verdam et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis

(2010) Ashkan Farhadi et al.   LIVER INTERNATIONAL

Effects of Probiotics, Prebiotics, and Synbiotics on Messenger RNA Expression of Caveolin-1, NOS, and Genes Regulating Oxidative Stress in the Terminal Ileum of Formula-Fed Neonatal Rats

(2010) Antoni D'Souza et al.   PEDIATRIC RESEARCH

Pulse Probiotic Administration Induces Repeated Small Intestinal Muc3 Expression in Rats

(2010) Natalie S Dykstra et al.   PEDIATRIC RESEARCH

Gene Expression Profiles Identify Inflammatory Signatures in Dendritic Cells

(2010) Anna Torri et al.   PLoS One

Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways

(2010) P. van Baarlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Toll-like receptors in the development of immunotolerance mediated by probiotics

(2010) Carolina Gómez-Llorente et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Adhesion and immunomodulatory effects ofBifidobacterium lactisHN019 on intestinal epithelial cells INT-407

(2010) Chang Liu   WORLD JOURNAL OF GASTROENTEROLOGY

Kupffer cell activation is a causal factor for hepatic insulin resistance

(2009) Nicolas Lanthier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Critical role of Kupffer cells in the management of diet-induced diabetes and obesity

(2009) Audrey M. Neyrinck et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Impact of Probiotic on Gut Health

(2009) Maria Collado et al.   CURRENT DRUG METABOLISM

Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota

(2009) Patrice D Cani et al.   CURRENT OPINION IN PHARMACOLOGY

The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease

(2009) Patrice Cani et al.   CURRENT PHARMACEUTICAL DESIGN

Modulation of the immune response by probiotic strains in a mouse model of gluten sensitivity

(2009) Rossana D’Arienzo et al.   CYTOKINE

Prebiotics, Probiotics and Helminths: The ‘Natural’ Solution?

(2009) Francisco Guarner   DIGESTIVE DISEASES

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Effect of natural commensal-origin DNA on toll-like receptor 9 (TLR9) signaling cascade, chemokine IL-8 expression, and barrier integritiy of polarized intestinal epithelial cells

(2009) Darab Ghadimi et al.   INFLAMMATORY BOWEL DISEASES

Effects of Live and Inactivated VSL#3 Probiotic Preparations in the Modulation of in vitro and in vivo Allergen-Induced Th2 Responses

(2009) Giorgia Mastrangeli et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Lactococcus lactis subsp. cremoris FC alleviates symptoms of colitis induced by dextran sulfate sodium in mice

(2009) Yosuke Nishitani et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Anti-inflammatory effects of the genusBifidobacteriumon macrophages by modification of phospho-IκB and SOCS gene expression

(2009) Yoshikiyo Okada et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

In vitro evaluation of Lactobacillus plantarum DSMZ 12028 as a probiotic: Emphasis on innate immunity

(2009) Marcella Cammarota et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Lactobacillus rhamnosus alleviates intestinal barrier dysfunction in part by increasing expression of zonula occludens-1 and myosin light-chain kinase in vivo

(2009) E. Miyauchi et al.   JOURNAL OF DAIRY SCIENCE

Modulation of cytokine gene expression in spleen and Peyer's patches by feeding dahi containing probioticLactobacillus caseiin mice

(2009) Shalini JAIN et al.   Journal of Digestive Diseases

Probiotics and immunity

(2009) Andrea T. Borchers et al.   JOURNAL OF GASTROENTEROLOGY

Therapeutic implications of manipulating and mining the microbiota

(2009) Fergus Shanahan   JOURNAL OF PHYSIOLOGY-LONDON

Multistep mechanism of probiotic bacterium, the effect on innate immune system

(2009) Einat Amit-Romach et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A plasmacytoid dendritic cell (CD123+/CD11c−) based assay system to predict contact allergenicity of chemicals

(2009) Seyoum Ayehunie et al.   TOXICOLOGY

Specific probiotics alleviate allergic rhinitis during the birch pollen season

(2009) Arthur C Ouwehand et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Immunostimulatory activity ofBacillusspores

(2008) Jen-Min Huang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Effect of fructo-oligosaccharides and different doses of Bifidobacterium animalis in a weaning diet on bacterial translocation and Toll-like receptor gene expression in pigs

(2008) Paolo Trevisi et al.   NUTRITION

The Probiotic Lactobacillus GG may Augment Intestinal Host Defense by Regulating Apoptosis and Promoting Cytoprotective Responses in the Developing Murine Gut

(2008) Patricia W Lin et al.   PEDIATRIC RESEARCH

Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells

(2008) Sinikka Latvala et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Anti-inflammatory activity of probiotic Bifidobacterium: Enhancement of IL-10 production in peripheral blood mononuclear cells from ulcerative colitis patients and inhibition of IL-8 secretion in HT-29 cells

(2008) Akemi Imaoka et al.   WORLD JOURNAL OF GASTROENTEROLOGY