Pancreatic cancer and its stroma: A conspiracy theory

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

(2013) Y Ino et al.   BRITISH JOURNAL OF CANCER

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Stromal expression of SPARC in pancreatic adenocarcinoma

(2013) Cindy Neuzillet et al.   CANCER AND METASTASIS REVIEWS

Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells

(2013) S. Kozono et al.   CANCER RESEARCH

Tumour–stroma interactions in pancreatic ductal adenocarcinoma: Rationale and current evidence for new therapeutic strategies

(2013) V. Heinemann et al.   CANCER TREATMENT REVIEWS

Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors

(2013) A. Jimeno et al.   CLINICAL CANCER RESEARCH

A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment

(2013) Minoti V. Apte et al.   GASTROENTEROLOGY

Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

(2013) Abasi Ene–Obong et al.   GASTROENTEROLOGY

Therapeutic Advances in Pancreatic Cancer

(2013) Andrew Scott Paulson et al.   GASTROENTEROLOGY

nab-Paclitaxel mechanisms of action and delivery

(2013) Denise A. Yardley   JOURNAL OF CONTROLLED RELEASE

Migratory Activity of CD105+ Pancreatic Cancer Cells Is Strongly Enhanced by Pancreatic Stellate Cells

(2013) Kenji Fujiwara et al.   PANCREAS

Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2

(2013) R. Maron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice

(2013) Atsushi Masamune et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway

(2013) Sherri Smith et al.   XENOBIOTICA

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

(2013) Vikash P. Chauhan et al.   Nature Communications

Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells

(2012) Shin Hamada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancers with increasing incidence trends in the United States: 1999 through 2008

(2012) Edgar P. Simard et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma

(2012) Ru Chen et al.   CANCER BIOLOGY & THERAPY

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

Incidence and survival for hepatic, pancreatic and biliary cancers in England between 1998 and 2007

(2012) Victoria H. Coupland et al.   Cancer Epidemiology

Activation of Nuclear Factor-κB in Acinar Cells Increases the Severity of Pancreatitis in Mice

(2012) Haojie Huang et al.   GASTROENTEROLOGY

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

(2012) Michael A Jacobetz et al.   GUT

CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB

(2012) Ajay P. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice

(2012) Jaroslaw Daniluk et al.   JOURNAL OF CLINICAL INVESTIGATION

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

(2012) Meredith A. Collins et al.   JOURNAL OF CLINICAL INVESTIGATION

Dangerous liaisons: Pancreatic stellate cells and pancreatic cancer cells

(2012) Minoti V Apte et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Epidemiology, risk factors, and the promotion of pancreatic cancer: Role of the stellate cell

(2012) Stephen Pandol et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

(2012) Tiago De Oliveira et al.   Molecular Cancer

Inhibition of the Hedgehog Pathway Targets the Tumor-Associated Stroma in Pancreatic Cancer

(2012) R. F. Hwang et al.   MOLECULAR CANCER RESEARCH

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

Trefoil Factor Family Peptides in Normal and Diseased Human Pancreas

(2012) Naomi J. Guppy et al.   PANCREAS

Stellate Cells from Rat Pancreas Are Stem Cells and Can Contribute to Liver Regeneration

(2012) Claus Kordes et al.   PLoS One

Pancreatic stellate cells: a starring role in normal and diseased pancreas

(2012) Minoti V. Apte et al.   Frontiers in Physiology

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence

(2011) Carmen Guerra et al.   CANCER CELL

Galectin-1 research in T cell immunity: Past, present and future

(2011) Filiberto Cedeno-Laurent et al.   CLINICAL IMMUNOLOGY

High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer

(2011) Dong Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

(2011) Hideaki Ijichi et al.   JOURNAL OF CLINICAL INVESTIGATION

Gemcitabine Plusnab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial

(2011) Daniel D. Von Hoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Trefoil Factor 1 Stimulates Both Pancreatic Cancer and Stellate Cells and Increases Metastasis

(2011) Thiruvengadam Arumugam et al.   PANCREAS

Precursor lesions in pancreatic cancer: morphological and molecular pathology

(2011) Christopher J. Scarlett et al.   PATHOLOGY

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis

(2010) Zhihong Xu et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of renin–angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine

(2010) Y Nakai et al.   BRITISH JOURNAL OF CANCER

CD10+ Pancreatic Stellate Cells Enhance the Progression of Pancreatic Cancer

(2010) Naoki Ikenaga et al.   GASTROENTEROLOGY

Molecular mechanism of pancreatic cancer—understanding proliferation, invasion, and metastasis

(2010) André L. Mihaljevic et al.   LANGENBECKS ARCHIVES OF SURGERY

Isolation of Quiescent Human Pancreatic Stellate Cells: A Promising in vitro Tool for Studies of Human Pancreatic Stellate Cell Biology

(2010) Alain Vonlaufena et al.   PANCREATOLOGY

Malignant cells facilitate lung metastasis by bringing their own soil

(2010) D. G. Duda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

Organotypic Culture Model of Pancreatic Cancer Demonstrates that Stromal Cells Modulate E-Cadherin, β-Catenin, and Ezrin Expression in Tumor Cells

(2009) Fieke E.M. Froeling et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas

(2009) Eugenia Mato et al.   BIOCHEMICAL JOURNAL

Germ-Line Mutations, Pancreatic Inflammation, and Pancreatic Cancer

(2009) David Whitcomb et al.   Clinical Gastroenterology and Hepatology

Ras Activity in Acinar Cells Links Chronic Pancreatitis and Pancreatic Cancer

(2009) Craig D. Logsdon et al.   Clinical Gastroenterology and Hepatology

Inflammation and pancreatic cancer: an evidence-based review

(2009) Julia B Greer et al.   CURRENT OPINION IN PHARMACOLOGY

Quantitative proteomics investigation of pancreatic intraepithelial neoplasia

(2009) Sheng Pan et al.   ELECTROPHORESIS

Ras Activity Levels Control the Development of Pancreatic Diseases

(2009) Baoan Ji et al.   GASTROENTEROLOGY

The Role of Nuclear Factor κB in Pancreatic Cancer and the Clinical Applications of Targeted Therapy

(2009) Bryan Holcomb et al.   PANCREAS

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

(2008) Atsushi Masamune et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pancreatic Stellate Cells: Partners in Crime with Pancreatic Cancer Cells

(2008) A. Vonlaufen et al.   CANCER RESEARCH

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer

(2008) J. M. Bailey et al.   CLINICAL CANCER RESEARCH

The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma

(2008) Mert Erkan et al.   Clinical Gastroenterology and Hepatology

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

(2008) G Feldmann et al.   GUT

Periostin deposition in the stroma of invasive and intraductal neoplasms of the pancreas

(2008) Noriyoshi Fukushima et al.   MODERN PATHOLOGY

Seeding and Propagation of Untransformed Mouse Mammary Cells in the Lung

(2008) K. Podsypanina et al.   SCIENCE