Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 18, Issue 8, Pages 746-753Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v18.i8.746
Keywords
Liver fibrosis; Noninvasive test; FibroQ; Aspartate aminotransferase; Alanine aminotransferase; FIB-4 index; Aspartate aminotransferase to platelet ratio index; Lok's model; Cirrhosis discriminant score; Pohl score
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Funding
- Chiayi Chang Gung Memorial Hospital [CMRPG 690081]
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AIM: To verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C, compared with other noninvasive tests. METHODS: This retrospective cohort study included 237 consecutive patients with chronic hepatits C who had undergone percutaneous liver biopsy before treatment. FibroQ, aspartate aminotransferase (AST)/alanine aminotransgerase ratio (AAR), AST to platelet ratio index, cirrhosis discriminant score, age-platelet index (API), Pohl score, FIB-4 index, and Lok's model were calculated and compared. RESULTS: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced (analysis of variance test: P < 0.001). FibroQ trended to be superior in predicting significant fibrosis score in chronic hepatitis C compared with other noninvasive tests. CONCLUSION: FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C. (C) 2012 Baishideng. All rights reserved.
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