Article
Radiology, Nuclear Medicine & Medical Imaging
Hui Zhang, Xu-Dong Wen, Xiao Ma, Yong-Qiang Zhu, Zhi-Wei Jiang, Shang-Qing Huang, Tao Wang, Wei-Hui Liu
Summary: The study retrospectively analyzed 73 patients with acute pancreatitis-related WON, comparing the outcomes of CUC-PCD and UC-PCD. Results showed that CUC-PCD group had significantly smaller infected WON size, lower inflammatory response indexes, shorter catheter duration, hospitalization duration, and global costs than the UC-PCD group. The CUC-PCD approach is safe and effective for treating infected WON due to its ability to place drainage catheters optimally and perform necrosectomy in real time.
INSIGHTS INTO IMAGING
(2021)
Article
Multidisciplinary Sciences
Tongtian Ni, Lili Xu, Silei Sun, Li Ma, Bing Zhao, Weijun Zhou, Yi Wen, Ning Ning, Erzhen Chen, Ying Chen, Enqiang Mao
Summary: FRVC can inhibit the expression of DC-SIGN in the colon tissue of SAP rats, helping to alleviate systemic inflammation and multi-organ injury in the early stages. Compared to intravenous fluid resuscitation, FRVC has advantages in reducing lung injury and decreasing serum TNF-alpha, IL-6, and LPS levels.
SCIENTIFIC REPORTS
(2021)
Review
Gastroenterology & Hepatology
Nian-Jun Xiao, Ting-Ting Cui, Fang Liu, Wen Li
Summary: Pancreatic and peripancreatic collections are common local complications of acute pancreatitis, which can develop into pancreatic pseudocyst or walled-off necrosis. Minimally invasive treatments, especially endoscopic techniques, have become the standard for severe complications, although complications such as pancreatic fistulae or stent-related issues should not be overlooked.
WORLD JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Article
Critical Care Medicine
Charlotte Garret, Marion Douillard, Arthur David, Morgane Pere, Lucille Queneherve, Ludivine Legros, Isabelle Archambeaud, Frederic Douane, Marc Lerhun, Nicolas Regenet, Jerome Gournay, Emmanuel Coron, Eric Frampas, Jean Reignier
Summary: This study aimed to evaluate the external validity of a nomogram for predicting catheter drainage failure and to identify other potential predictors of failure. The study found that over half of the patients required necrosectomy after failed catheter drainage. Newly identified predictors of catheter-drainage failure were heterogeneous collection and respiratory failure. Adding these predictors to the nomogram might help identify patients at high risk of catheter-drainage failure.
ANNALS OF INTENSIVE CARE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mesut Ozturk, Orhan Ozkan, Paul Laeseke, Mark G. Kleedehn
Summary: The percutaneous drainage of peripancreatic fluid collections after pancreas transplant is safe and effective, with a success rate of 82.1%. Factors such as duration of drainage, collection volume, and bacterial growth were associated with the clinical outcome.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Dermatology
Le Cao, Ran Zeng, Kai Sun, Haitao Fan
Summary: This study compared the efficacy of closed suction irrigation (CSI) and microtube drainage in treating deep surgical site infection (SSI) after spinal surgery. The results showed that patients with microtube drainage had shorter hospital stays, lower costs, and higher functional scores at 3 and 6 months postoperatively.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Harsimran Bhatia, Shameema Farook, Chaitanya Uday Bendale, Pankaj Gupta, Anupam K. Singh, Jimil Shah, Jayanta Samanta, Harshal Mandavdhare, Vishal Sharma, Saroj K. Sinha, Vikas Gupta, Thakur Deen Yadav, Usha Dutta, Manavjit Singh Sandhu, Rakesh Kochhar
Summary: Early percutaneous catheter drainage (PCD) is technically successful in the management of acute necrotic collections (ANC), but it is associated with a higher surgical rate and a higher incidence of complications compared to late PCD.
ABDOMINAL RADIOLOGY
(2023)
Article
Medicine, General & Internal
Pankaj Gupta, Gaurav Chayan Das, Akash Bansal, Jayanta Samanta, Harshal S. Mandavdhare, Vishal Sharma, Shano Naseem, Vikas Gupta, Thakur Deen Yadav, Usha Dutta, Neelam Varma, Manavjit Singh Sandhu, Rakesh Kochhar
Summary: This study aimed to assess the value of white blood cell (WBC) count and neutrophil-lymphocyte ratio (NLR) in predicting response to percutaneous catheter drainage (PCD) in patients with acute necrotizing pancreatitis (AP). The results showed that WBC and NLR can be used as simple tests to predict patients' response to PCD.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Review
Medicine, General & Internal
Akash Bansal, Pankaj Gupta, Anupam K. Singh, Jimil Shah, Jayanta Samanta, Harshal S. Mandavdhare, Vishal Sharma, Saroj Kant Sinha, Usha Dutta, Manavjit Singh Sandhu, Rakesh Kochhar
Summary: Moderately severe and severe acute pancreatitis are characterized by local and systemic complications. Local complications, such as necrotic fluid collections, are important in the late phase of the disease and require drainage. Different drainage methods have their own advantages and disadvantages and are often used in combination.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Medicine, General & Internal
Dong Wook Lee, Ho Gak Kim, Chang Min Cho, Min Kyu Jung, Jun Heo, Kwang Bum Cho, Sung Bum Kim, Kook Hyun Kim, Tae Nyeun Kim, Jimin Han, Hyunsoo Kim
Summary: In patients with acute pancreatitis, the natural course of APFC can vary greatly, including spontaneous resolution, transformation into pseudocyst or walled-off necrosis. High BISAP score, elevated CRP level after 48 hours of admission, and non-improved abdominal pain are risk factors for developing late complications.
MEDICINA-LITHUANIA
(2022)
Article
Surgery
Venu Bhargava, Rahul Gupta, Prateek Vaswani, Bhairavi Jha, Surinder Singh Rana, Ujwal Gorsi, Mandeep Kang, Rajesh Gupta
Summary: The study aimed to evaluate the impact of streptokinase irrigation in pancreatic necrosis patients undergoing percutaneous catheter drainage. The results showed a significantly higher sepsis reversal rate, lower need for necrosectomy, lower mortality rate, and decreased incidence of bleeding in the streptokinase group. Additionally, a higher dose of 150,000 IU streptokinase resulted in better outcomes compared to 50,000 IU streptokinase.
Article
Surgery
Yang Yang, Jianhua Li, Zhengqi Chang
Summary: This study evaluated the safety and efficacy of percutaneous endoscopic debridement and drainage for early epidural abscess in the lumbar region. Eight patients with early epidural abscess underwent lumbar intervertebral space debridement and drainage. The results showed that this treatment method effectively eliminated the abscess and improved the patients' pain and neurological function.
FRONTIERS IN SURGERY
(2023)
Article
Medicine, General & Internal
Satwant Singh, Siddharth Prakash, Deepak Kaushal, Honey Chahal, Ajit Sood
Summary: The study demonstrates that percutaneous catheter drainage (PCD) is safe and effective in patients with acute infected necrotizing pancreatitis, benefiting one-third of patients as standalone therapy and delaying surgery beyond four weeks to prevent complications of early aggressive debridement.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Pharmacology & Pharmacy
Chuanmin Liu, Fei Yuan, Baowei Wang, Xuezhen Wang
Summary: The combination of ultrasound-guided percutaneous APD with ulinastatin has shown significant benefits for patients with severe acute pancreatitis. The treatment group exhibited better clinical outcomes, faster normalization of indicator levels, and reduced incidence of postoperative complications compared to the control group.
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
(2021)
Article
Gastroenterology & Hepatology
Juliane Glaubitz, Anika Wilden, Fabian Frost, Sabine Ameling, Georg Homuth, Hala Mazloum, Malte Christoph Ruehlemann, Corinna Bang, Ali A. Aghdassi, Christoph Budde, Tilmann Pickartz, Andre Franke, Barbara M. Broeker, Uwe Voelker, Julia Mayerle, Markus M. Lerch, Frank-Ulrich Weiss, Matthias Sendler
Summary: Understanding the role of T-reg/Th17 balance in maintaining intestinal barrier function is important for reducing the risk of severe disease and late death in acute pancreatitis (AP). Depletion of T-reg cells enhances the proinflammatory response and reduces bacterial translocation to the pancreas in a mouse model of AP. Targeting T-regs may help improve the course of the disease.
