Article
Oncology
Ling Han, Yali Chen, Ai Zheng, Hengxi Chen
Summary: In recent years, there has been increased attention to the relationship between neoadjuvant chemotherapy (NACT) in ovarian cancer and the incidence of venous thromboembolism (VTE). This study conducted a systematic review and meta-analysis to investigate the incidence of VTE during NACT and its associated risk factors. The analysis included 7 cohort studies with 1244 participants and found a pooled VTE rate of 13% during NACT, with body mass index identified as a risk factor.
AMERICAN JOURNAL OF CANCER RESEARCH
(2023)
Article
Oncology
Hirona Shigyo, Hiroyuki Suzuki, Toshimitsu Tanaka, Etsuko Moriyama, Yasutaka Shimotsuura, Sachiko Nagasu, Hideki Iwamoto, Yoshito Akagi, Kenta Murotani, Takumi Kawaguchi, Keisuke Miwa
Summary: This study aimed to investigate the safety of Bevacizumab administration early after central venous (CV) port placement. The results showed that the timing of Bevacizumab initiation did not affect the frequency of complications. Therefore, it is safe to administer Bevacizumab early after CV port placement.
Article
Medicine, General & Internal
Jonathan G. Moss, Olivia Wu, Andrew R. Bodenham, Roshan Agarwal, Tobias F. Menne, Brian L. Jones, Robert Heggie, Steve Hill, Judith Dixon-Hughes, Eileen Soulis, Evi Germeni, Susan Dillon, Elaine McCartney
Summary: This study compared complication rates and costs of PICCs, Hickman, and PORTs in patients receiving SACT, finding that PORTs were more effective and safer than both Hickman and PICCs.
Article
Geriatrics & Gerontology
Takehito Shukuya, Kazuhisa Takahashi, Yasushi Shintani, Keita Miura, Ikuo Sekine, Koichi Takayama, Akira Inoue, Isamu Okamoto, Katsuyuki Kiura, Tomoya Kawaguchi, Nobuyuki Yamamoto, Etsuo Miyaoka, Ichiro Yoshino, Hiroshi Date
Summary: This study examined the epidemiology, risk factors, and impact of cancer cachexia on chemotherapy response rate and prognosis in lung cancer patients. Cancer cachexia significantly affects a patient's quality of life and prognosis. Understanding these factors related to cancer cachexia is crucial for overcoming it in lung cancer patients.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Public, Environmental & Occupational Health
Guoliang Shao, Xiaoying Zhou, Shaoya Zhang, Shuaijun Wu, Yichen Dong, Zuojun Dong
Summary: This study compared the cost-utility of PICCs and PORTs and found that PORTs were more cost-effective than PICCs for a 6 and 12-month dwell time.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Oncology
Jumpei Shibata, Hidetaka Kawamura, Kazuhiro Hiramatsu, Michitaka Honda, Yoshihisa Shibata, Taro Aoba, Masahiro Fujii, Atsuki Arimoto, Akira Ito, Kenta Ishii, Kojiro Omiya, Mariko Asai, Takuya Arakawa, Hirotake Gonda, Shuhei Asai, Takuya Hasegawa, Kento Kawashima, Takehito Kato
Summary: In this study, there was a significant association between the midclavicular line subcutaneous fat area (SFA) and infectious complications, but no significant association was found between SFA and overall complications.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Surgery
Hanna Jung, Joon Yong Cho, Yangki Seok, Youngok Lee
Summary: Totally implantable central venous access ports (TICVAPs) are increasingly used in pediatric patients due to reliable venous access, but complications such as stuck fragments during removal have been reported. This study retrospectively analyzed 121 patients and found that male patients with acute leukemia who used TICVAPs for chemotherapy were more likely to have fragments stuck during removal. Recommendations include prophylactic catheter exchange before 46 months of use and monitoring weight changes to prevent complications, especially in rapidly growing leukemia patients. Management of stuck fragments in asymptomatic patients should involve careful observation rather than aggressive treatment.
Review
Oncology
Lu Ye, Li Cai, Yonghui Fu, Debao Zhuang, Xiaoqing Hu, Youkun Jie
Summary: This study revealed that the prevalence of chemotherapy-related VTE in ovarian cancer patients was approximately 9%. Significant risk factors for chemotherapy-related VTE were identified, which may contribute to targeting potentially preventative measures for VTE in ovarian cancer. The prognostic value of VTE in ovarian cancer patients receiving chemotherapy remains inconclusive and further research is needed.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
Chiara A. Cella, Maren Knoedler, Marcia Hall, Michele Arcopinto, Vincenzo Bagnardi, Lorenzo Gervaso, Stefania Pellicori, Francesca Spada, Maria G. Zampino, Paola S. Ravenda, Samuele Frassoni, Antonio Passaro, Monica Milano, Alice Laffi, Nicola Fazio, Florian Lordick
Summary: The study validates the ONKOTEV score as a reliable risk assessment model for cancer-associated thrombosis, and suggests its adoption into clinical practice as a decision-making tool for primary prophylaxis.
Review
Medicine, General & Internal
Ming-Yee Sun, Sonu M. M. Bhaskar
Summary: This study aimed to calculate the pooled prevalence of VTE in chemotherapy-treated cancer patients, finding a prevalence rate of 6% which is higher than the overall crude prevalence rate. Comprehensive cancer care should consider stratified VTE risk assessment based on cancer phenotype.
Review
Oncology
Li Lin, Wei Li, Chen Chen, Anhua Wei, Yu Liu
Summary: This study compared the clinical effects and adverse effects of implanted vascular access ports (PORTs) and peripherally inserted central catheters (PICCs) for chemotherapy. The results showed that PORT had a superior safety profile, with lower incidences of overall adverse effects, catheter-related thrombosis, and allergic reactions compared to PICC. However, PICC was non-inferior to PORT in terms of deep vein thrombosis (DVT) and infection. In conclusion, PORT is considered a safe and effective vascular access for chemotherapy.
FRONTIERS IN ONCOLOGY
(2023)
Editorial Material
Oncology
Shogo Kumagai, Shohei Koyama, Kohei Shitara
Summary: Studies have shown that immunochemotherapy is the preferred treatment for advanced esophageal cancer. Chen et al. and Carrol et al. conducted exploratory analysis of the JUPITER-06 and LUD2015-005 trials, respectively, and identified biomarkers for predicting treatment response through immunogenomic analysis. These findings can potentially improve patient stratification in advanced esophageal cancer.
Article
Multidisciplinary Sciences
Benedikte Paulsen, Olga V. Gran, Marianne T. Severinsen, Jens Hammerstrom, Soren R. Kristensen, Suzanne C. Cannegieter, Hanne Skille, Anne Tjonneland, Frits R. Rosendaal, Kim Overvad, Inger Anne Naess, John-Bjarne Hansen, Sigrid K. Braekkan
Summary: Smoking is associated with increased risk of VTE in subjects with active cancer, but no association was found in those without cancer. The risk of VTE among smokers with cancer remained unchanged after adjustment for cancer site and metastasis. The findings imply a biological interaction between cancer and smoking on the risk of VTE.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Mariko Kamiya, Shinnosuke Kawahara, Yuto Kamioka, Masaaki Murakawa, Toru Aoyama, Satoshi Kobayashi, Makoto Ueno, Naoto Yamamoto, Takashi Oshima, Norio Yukawa, Yasushi Rino, Munetaka Masuda, Soichiro Morinaga
Summary: Pancreatic cancer patients receiving neoadjuvant chemotherapy have an increased risk of venous thromboembolism (VTE). This study retrospectively evaluated the incidence, risk, and predictors of VTE in patients with resectable pancreatic cancer who received neoadjuvant chemotherapy followed by surgery. The results showed that preoperative D-dimer level was the only predictor for VTE in these patients.
ANTICANCER RESEARCH
(2023)
Article
Hematology
Wilson L. Jr Jr da Costa, Danielle Guffey, Abiodun Oluyomi, Raka Bandyo, Omar Rosales, Courtney D. Wallace, Carolina Granada, Nimrah Riaz, Margaret Fitzgerald, David A. Garcia, Marc Carrier, Christopher Amos, Christopher R. Flowers, Ang Li
Summary: This study investigates the epidemiology of cancer-associated thrombosis (CAT) among uninsured and vulnerable populations in the US. The findings show a high incidence of CAT in these patients and identify several risk factors associated with CAT. Additionally, Hispanics have lower rates of CAT and mortality.
AMERICAN JOURNAL OF HEMATOLOGY
(2022)
Article
Environmental Sciences
Yali Xie, Shengke Yang, Zongzhou Wang, Ruixin Hu, Siqi Shen, Dan Zhang, Mengya Luo, Wenke Wang
Summary: This study explored the adsorption and hydrolysis characteristics of antibiotics in different environments by simulating the hyporheic zone. The results showed that the adsorption capacity and hydrolysis rate of antibiotics were influenced by the environmental conditions, and there were differences between surface water and groundwater.
POLISH JOURNAL OF ENVIRONMENTAL STUDIES
(2022)
Article
Biochemistry & Molecular Biology
Yi-Ting Pan, Yuan-Hsiung Tsai, Jiann-Der Lee, Hsu-Huei Weng, Jen-Tsung Yang, Yen-Chu Huang
Summary: This study aimed to evaluate the clinical relevance and underlying pathology of hemodynamic compromise in acute small subcortical infarction (SSI) using MRI-based neuroimaging markers. The results showed that hemodynamic compromise was highly related to early neurological deterioration (END), basal ganglia EPVS, and branch atheromatous disease.
BIOMEDICAL JOURNAL
(2023)
Article
Biodiversity Conservation
Yuanyuan Shen, Yu Ji, Wenke Wang, Tianpeng Gao, Haijuan Li, Mingyan Xiao
Summary: This study investigated the effects of Ryegrass on bacterial community and diversity in petroleum contaminated soil. High-throughput sequencing technology was used to compare the bacterial communities in 14 groups samples at different repair stages. The study found that different responses were observed to promote or inhibit microbial reproduction, and the repair time has a vital effect on microbial community changes.
HUMAN AND ECOLOGICAL RISK ASSESSMENT
(2023)
Article
Materials Science, Multidisciplinary
Wenke Wang, Jaimyun Jung, Chao Cui, Wenzhen Chen, Yang Yu, Peng Li, Wencong Zhang, Renlong Xiong, Hyoung Seop Kim
Summary: This work investigated the anisotropy variation of tensile flow stress for AZ31 magnesium alloys at different temperatures and tensile strains using the visco-plastic self-consistent model. The results showed that the anisotropy of flow stress weakened with increasing temperature and exhibited a slightly increasing stage followed by a continuously decreasing stage with increasing strain. Activation of basal slip and tension twinning contributed to the development of a (0002)//LD type texture during tension deformation, while activation of prismatic slip produced a < 10-10 >//LD type texture. The study found that the macroscopic average resolved shear stress decreased significantly with increasing temperature or strain, resulting in the decline of the tension deformation behavior anisotropy.
METALS AND MATERIALS INTERNATIONAL
(2023)
Article
Materials Science, Multidisciplinary
Wenzhen Chen, Manman Yuan, Wenke Wang, Jun Yu, Wencong Zhang, Tianyue Teng
Summary: In this study, the effects of surface bending and base bending on the bending strength and microstructure variation of friction stir welded ZM6 magnesium alloy sheet are compared. The results show that different bending methods produce different microstructure variations, resulting in changes in yield strength.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Metallurgy & Metallurgical Engineering
Wen-cong Zhang, Xin-tong Liu, Jun-fei Ma, Wen-ke Wang, Wen-zhen Chen, Yu-xuan Liu, Jian-lei Yang
Summary: Asymmetric lowered-temperature rolling was used to fabricate fine-grained ZK60 magnesium alloy sheet with weak basal texture. The results showed that multi-pass loweredtemperature rolling could improve microstructure homogeneity and refine the grain size. During the rolling process, a fiber texture along the transverse direction gradually developed. The shear deformation along the rolling direction weakened the basal texture along this direction, resulting in a decrease in yield strength.
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
(2022)
Article
Ecology
Ruyi Feng, Lei Duan, Siqi Shen, Yan Cheng, Yanhua Wang, Wenke Wang, Shengke Yang
Summary: The widespread spread of antibiotic resistance genes (ARGs) in the hyporheic zone (HZ) is a growing environmental problem. This research investigates the effects of oxygen changes, temperature, and salinity on the abundance of ARGs in the HZ. It also analyzes the bacterial community composition of sediment samples and their relationship with ARGs. The study reveals that changes in bacterial communities, oxygen conditions, and horizontal gene transfer (HGT) of mobile genetic elements (MGEs) play significant roles in the spread of ARGs.
Article
Chemistry, Physical
Wenke Wang, Xinhua Liu, Zhihao Wang, Miaomiao Chen, Wenzhen Chen, Wencong Zhang, Hyoung Seop Kim
Summary: This study investigates the effects of asymmetric basal texture on the stretchability and microstructure variations of magnesium alloy sheet. The results show that plastic deformation is concentrated in the central region of the sample during stretch forming, and the transverse direction sample has higher stretch formability. This is attributed to the weak basal texture in the transverse direction sample, which activates more basal slip and tension twinning. Additionally, the activation of basal slip narrows the spread angle of the basal pole for the transverse direction sample, while only increasing the basal texture intensity for the rolling direction sample.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Engineering, Civil
Wenke Wang, Xinlin Guo, Yang Liu, Aomei Tang, Qin Yang
Summary: This study constructed a conceptual model of unsafe behaviors in UAV flight based on the Swiss cheese model and investigated the influence mechanism of these behaviors using social network analysis. The findings showed that unreasonable safety management structure and weak supervision were major factors contributing to unsafe UAV flight. It is recommended to eliminate critical unsafe behaviors in UAV supervision to improve flight safety.
TRANSPORTATION RESEARCH RECORD
(2023)
Article
Chemistry, Physical
Wenke Wang, Guoqing Yan, Zhaohui Ma, Jiandong Zhang, Lijun Wang, Zhancheng Guo
Summary: In this study, nitride films were successfully prepared as hydrogen permeation barriers on zirconium hydride. The growth of the film was mainly influenced by temperature, followed by the reaction atmosphere and holding time. Hydrogen was found to increase the diffusivity of nitrogen during film formation. The chemical composition of the film mainly consisted of Zr and N, with minor amounts of O. The film exhibited superior hydrogen permeation resistance compared to previously reported ZrO2 films. The hydrogen permeation resistance was attributed to chemical capture of hydrogen, physical barrier of the dense film, and different nitrogen diffusion coefficients at different temperatures.
Article
Nanoscience & Nanotechnology
Yangju Feng, Yunbin Lu, Xuesong Liu, Hongyang Cao, Wenke Wang, Jianlei Yang, Wenzhen Chen, Guorong Cui
Summary: In this paper, a novel columnar network structure reinforced TiBw/TA15 composites with excellent strength and high plasticity have been designed and prepared. The study showed that the columnar network structure effectively strengthened the grain boundary of the high temperature beta phase, enhancing the strength of the composites. The presence of TiBw hindered the movement of dislocations and provided a favorable condition for dynamic recrystallization of the matrix, leading to decreased dislocation density, refined grains, and improved plasticity. As a result, an effective combination of strength and plasticity was achieved in the composites.
SCRIPTA MATERIALIA
(2023)
Article
Environmental Sciences
Wenke Wang, Jianlong Wang, Bibo Lu, Boyuan Liu, Yake Zhang, Chunyang Wang
Summary: A mixed convolutional parallel transformer (MCPT) model based on Vision transformers (ViT) is proposed for fast PolSAR image classification. The method introduces mixed depthwise convolution tokenization to reduce computational and parameter complexity and extract features of different receptive fields. It implements a parallel encoder by pairing the same modules and decreases the network depth and computing power requirement. Experimental results show significant improvement in training and prediction speed, with overall accuracy of 97.9% and 96.77% achieved on AIRSAR Flevoland and RADARSAT-2 San Francisco datasets, respectively.
Article
Materials Science, Multidisciplinary
Wenzhen Chen, Wenjie Wu, Wenke Wang, Wencong Zhang, Xinhua Liu, Hyoung Seop Kim
Summary: Texture adjusting approaches were proposed to improve tension-compression asymmetry in magnesium alloys. The dominant deformation mechanism during yielding was quantified based on Sachs assumption and primarily manifested as twinning inhibition and transition between twinning and slip. The impacts on yield strength and asymmetry were estimated by modified Hall-Petch relationship. Slight texture adjustments, particularly of basal texture divergence, can significantly improve strength asymmetry while avoiding severe strength loss, illustrating the importance and potential of texture adjustment in engineering.
MATERIALS RESEARCH LETTERS
(2023)
Article
Water Resources
Gang Qiao, Feng-dan Yu, Wen-ke Wang, Jun Zhang, Hua-qing Chen
Summary: In this study, the temporal and spatial variation of heat budget and thermodynamic transmission process of the vadose zone in high and cold regions were analyzed by studying the moisture content of the vadose zone in alpine regions. The results showed a positive correlation between air temperature, ground temperature, and water content of the vadose zone. The thermodynamic transfer process of the vadose zone was divided into four stages based on the change law of geothermal gradient. This research provides valuable insights for understanding evapotranspiration and protecting the ecological and geological environment in high and cold regions.
JOURNAL OF GROUNDWATER SCIENCE AND ENGINEERING
(2022)
Article
Engineering, Electrical & Electronic
Xueyuan Liu, Bing Sun, Xiao Li, Zhen Zhang, Wenke Wang, Xin'gang Zhang, Zhi Huang, Huaping Liu, Hudong Chang, Rui Jia, Honggang Liu
Summary: Carbon nanotubes (CNTs) have great potential in the field of electronic hardware as a replacement for silicon devices. By combining CNTs as channel material and TiN floating gate, the device state and logic computing can be flexibly controlled. The combination of logic and memory properties will be applied in areas such as in-memory computing and field-programmable gate arrays.
ACS APPLIED ELECTRONIC MATERIALS
(2022)
