Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 15, Issue 46, Pages 5770-5775Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.15.5770
Keywords
Confocal microscopy; Diagnostic imaging; Gastrointestinal neoplasms; Precancerous conditions; Endoscopy; Virtual histology
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Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope, or into trans-endoscopic probes, a technique now known as confocal endomicroscopy or confocal laser endomicroscopy. This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or virtual biopsies of the gastrointestinal mucosa during endoscopy, and has stimulated significant interest in the application of this technique in clinical gastroenterology. This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future, particularly in the screening or surveillance of gastrointestinal neoplasia. (C) 2009 The WJG Press and Baishideng. All rights reserved
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