Article
Environmental Sciences
Hui Chen, Yongxiang Qin, Jiawei Pu, Jinxing Hu, Yuezhong Wen
Summary: This study investigated the toxicity of the chiral synthetic auxin herbicide DCPP to Arabidopsis, as well as the mutual regulation of NO, H2O2, O-2, and phytohormones at the enantiomeric level. The results revealed the important role of ROS in the enantioselective effect of DCPP and the potential redistribution of phytohormones between leaves and roots.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Multidisciplinary
Yuxuan Ma, Zhangwei Lu, Bin Jia, Ye Shi, Jun Dong, Shuoxing Jiang, Zhe Li
Summary: This study introduces a targeted treatment for rheumatoid arthritis (RA) using folic acid-modified triangular DNA origami nanostructures (FA-tDONs). The FA-tDONs can efficiently scavenge reactive oxygen species (ROS) and nitric oxide (NO), leading to the transition of pro-inflammatory macrophages to an anti-inflammatory phenotype. In an RA mouse model, FA-tDONs treatment effectively alleviates synovial inflammation and cartilage damage, attenuating disease progression.
Article
Plant Sciences
Yu-Ying Sun, Jia-Qi Wang, Ru-Hua Xiang, Zhong-Guang Li
Summary: This study found that nitric oxide (NO) can enhance thermotolerance in maize seedlings by triggering the LCD/H2S signaling pathway. Additionally, NO also improves the adaptability of maize seedlings to heat stress by regulating the activity of the ROS scavenging system.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Zhiwei Huang, Yannan Shi, Hengcai Wang, Changju Chun, Longwang Chen, Kang Wang, Zhongqiu Lu, Yingzheng Zhao, Xinze Li
Summary: This study utilized chitosan-bilirubin nanoparticles to treat gastric ulcers through anti-inflammatory and antioxidant mechanisms, demonstrating their efficacy in in vitro and in vivo studies. The findings provide a novel approach for prophylaxis against or treatment of gastric ulcers.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Plant Sciences
Indrani Manna, Saikat Sahoo, Maumita Bandyopadhyay
Summary: Researchers have found that nickel oxide nanoparticles affect the exposed roots of Allium cepa by disrupting cell membranes and being internalized within cell organelles, leading to disturbances in cellular homeostasis and survival. This external intervention causes changes in the cellular environment, reflected in crucial biochemical profiles.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Wenrui Dai, Shao Zhang, Huan Shang, Shuning Xiao, Zhangliu Tian, Wenbo Fan, Xiaolang Chen, Shike Wang, Wei Chen, Dieqing Zhang
Summary: Semiconductor photocatalytic technology has the potential to efficiently reduce low concentrations of gaseous nitric oxide (NO), but the suboptimal selectivity in NO removal is a challenge. In this study, a defective CdS/Na2Ti3O7 heterostructure is designed to promote charge transfer kinetics and refine reactive oxygen species (ROS) generation, leading to high selectivity and catalytic activity in NO removal.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Plant Sciences
Cheng Zhang, Zhiqiang Song, Pinyuan Jin, Xiuhong Zhou, Huajian Zhang
Summary: Xylooligosaccharides (XOS), major byproducts of biofuel production, can trigger stomatal closure in Arabidopsis by inducing the production of ROS and NO, mediated by salicylic acid signaling and independent of ABA signaling.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Chemistry, Multidisciplinary
Dongzhi Xue, Yue Cao, Yinghui Wang, Zhijia Lv, Longhai Jin, Songtao Zhang, Wanying Li, Junduo Wu, Jianhua Liu, Shuyan Song, Xiaogang Liu, Hongjie Zhang
Summary: A novel theranostic nanoagent GLIF based on Gd2(WO4)3:Nd3+ nanoparticles loaded with ploy-L-arginine (PLA), indocyanine green (ICG), and lactoferrin (LF) has been developed for efficient low-dose drug therapy and imaging diagnosis of glioblastoma. GLIF showed significant therapeutic effect and diagnostic performance in vitro and in vivo.
Review
Plant Sciences
Dandan Huang, Guangqin Jing, Lili Zhang, Changbao Chen, Shuhua Zhu
Summary: NO, H2S, and ROS play essential signaling roles in cells through oxidative post-translational modification within suitable ranges of concentration to maintain redox balance and regulate DNA repair pathways, including mtDNA. The interactions among them are intricate, influencing their generation, elimination, and signaling actions. Additionally, NO and H2S may be involved in epigenetic variations in DNA damage repair of plants.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Ji-Hye Lee, Hiroshi Uyama, Oh-Kyoung Kwon, Young-Jin Kim
Summary: The study explores the integration of multi-modal therapies using a PLIN monolith to enhance PTT efficacy in treating osteosarcomas and regenerating bone defects. The PLIN monolith exhibits enhanced photothermal activity on osteosarcomas without causing phototoxicity in normal osteoblasts, and induces significant apoptotic cell death in cancer cells.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Martina Janku, Tereza Jedelska, Lucie Cincalova, Antonin Sedlar, Jaromir Mikulik, Lenka Luhova, Jan Lochman, Marek Petrivalsky
Summary: Elicitins are proteinaceous elicitors that enhance plant defense by inducing hypersensitive response and resistance to phytopathogens. They trigger a variety of responses through recognition by membrane receptors or high-affinity sites, including production of reactive oxygen species and nitric oxide. Different types of elicitins have varying abilities to induce cell death, ROS and phytohormones. Specific lysine and valine residues play key roles in their biological activity and enhancement of necrotic effects.
Article
Environmental Sciences
Ravi Gautam, JiHun Jo, Manju Acharya, Anju Maharjan, DaEun Lee, K. C. Pramod Bahadur, ChangYul Kim, KilSoo Kim, HyoungAh Kim, Yong Heo
Summary: Polyethylene microplastics (PE-MPs) have different effects on human cells, depending on the size of the microplastics, cell type, and tissue. PE-MPs can induce intracellular oxidative stress and inflammatory response, but the effects vary among different cell lines.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Cell Biology
Bhupesh Singla, Ravi Varma Aithabathula, Sonia Kiran, Shweta Kapil, Santosh Kumar, Udai P. Singh
Summary: The lymphatic system plays a crucial role in immune surveillance and tissue homeostasis, and lymphangiogenesis, the formation of new lymphatic vessels, is involved in various physiological and pathological processes. Recent research progress in the molecular mechanisms of lymphangiogenesis has opened up new possibilities for therapeutic approaches in diseases such as neurological disorders, cardiac repair, autoimmune disease, obesity, and atherosclerosis.
Article
Medicine, Research & Experimental
Xiang Gao, Kou Liu, Chengyang Hu, Keyang Chen, Zhengxuan Jiang
Summary: This study demonstrates that captopril alleviates oxidative damage in diabetic retinopathy by reducing reactive oxygen species (ROS) and nitric oxide (NO) levels, thereby reducing peroxynitrite formation. These findings provide new directions for research in diabetic retinopathy.
Article
Biochemistry & Molecular Biology
Diana Ramirez-Hernandez, Pedro Lopez-Sanchez, Martha C. Rosales-Hernandez, Salvador Fonseca-Coronado, Jazmin Flores-Monroy
Summary: The research found that the infarct area decreased in the proestrus group, while it increased in the estrus and OVX groups. Left ventricular systolic pressure and +/- dP/dt were reduced in the OVX groups, but left ventricular diastolic pressure increased. NO levels increased in the OVX + CO and estrus + CO groups, while ROS levels increased in OVX rats after myocardial infarction but remained unchanged in the proestrus and estrus groups.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2021)