Multiple levels of impaired neural plasticity and cellular resilience in bipolar disorder: Developing treatments using an integrated translational approach

Effect of Bcl-2 rs956572 Polymorphism on Age-Related Gray Matter Volume Changes

(2013) Mu-En Liu et al.   PLoS One

Translating neurotrophic and cellular plasticity: from pathophysiology to improved therapeutics for bipolar disorder

(2012) M. G. Soeiro-de-Souza et al.   ACTA PSYCHIATRICA SCANDINAVICA

Meta-analysis of genetic association studies on bipolar disorder

(2012) Fayaz Seifuddin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development

(2012) Andrew A Nierenberg et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial

(2012) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

State-related alterations of gene expression in bipolar disorder: a systematic review

(2012) Klaus Munkholm et al.   BIPOLAR DISORDERS

Neuroprogression in bipolar disorder

(2012) Marguerite Reid Schneider et al.   BIPOLAR DISORDERS

DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects

(2012) Carinna M. Torgerson et al.   Brain Imaging and Behavior

A Randomized, Placebo-Controlled, Crossover Pilot Trial of the Oral Selective NR2B Antagonist MK-0657 in Patients With Treatment-Resistant Major Depressive Disorder

(2012) Lobna Ibrahim et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study

(2012) Lobna Ibrahim et al.   NEUROPSYCHOPHARMACOLOGY

Neurometabolites in schizophrenia and bipolar disorder — A systematic review and meta-analysis

(2012) Nina Vanessa Kraguljac et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Morphometric post-mortem studies in bipolar disorder: possible association with oxidative stress and apoptosis

(2011) Alexandre Duarte Gigante et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Mitochondria, oligodendrocytes and inflammation in bipolar disorder: Evidence from transcriptome studies points to intriguing parallels with multiple sclerosis

(2011) Christine Konradi et al.   NEUROBIOLOGY OF DISEASE

Cross-Disorder Analysis of Bipolar Risk Genes: Further Evidence of DGKH as a Risk Gene for Bipolar Disorder, but also Unipolar Depression and Adult ADHD

(2011) Heike Weber et al.   NEUROPSYCHOPHARMACOLOGY

Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: A preliminary 4-week study

(2011) Rafael T. de Sousa et al.   NEUROSCIENCE LETTERS

Novel glutamatergic agents for major depressive disorder and bipolar disorder

(2011) Rodrigo Machado-Vieira et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A meta-analysis of whole-brain diffusion tensor imaging studies in bipolar disorder

(2011) François-Eric Vederine et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The Role of BDNF as a Mediator of Neuroplasticity in Bipolar Disorder

(2011) Iria Grande et al.   Psychiatry Investigation

Oxidative stress caused by mitochondrial calcium overload

(2010) Tsung-I Peng et al.   Annals of the New York Academy of Sciences

Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood Disorders

(2010) Cagri Yüksel et al.   BIOLOGICAL PSYCHIATRY

Voxelwise Meta-Analysis of Gray Matter Abnormalities in Bipolar Disorder

(2010) Emre Bora et al.   BIOLOGICAL PSYCHIATRY

The Bcl-2 Gene Polymorphism rs956572AA Increases Inositol 1,4,5-Trisphosphate Receptor–Mediated Endoplasmic Reticulum Calcium Release in Subjects with Bipolar Disorder

(2010) Rodrigo Machado-Vieira et al.   BIOLOGICAL PSYCHIATRY

Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

(2010) Hayley B. Clay et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

(2010) Nancy DiazGranados et al.   JOURNAL OF CLINICAL PSYCHIATRY

Novel Insights into Lithium’s Mechanism of Action: Neurotrophic and Neuroprotective Effects

(2010) Jorge A. Quiroz et al.   NEUROPSYCHOBIOLOGY

Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

(2010) Xiaohua Li et al.   NEUROPSYCHOPHARMACOLOGY

Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors

(2010) M. Berk et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Glutamatergic Modulators: The Future of Treating Mood Disorders?

(2010) Carlos Zarate et al.   HARVARD REVIEW OF PSYCHIATRY

The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis

(2009) Rodrigo Machado-Vieira et al.   BIPOLAR DISORDERS

Protein Kinase C Inhibitors

(2009) Carlos A. Zarate et al.   CNS DRUGS

A Longitudinal Study of the Effects of Lithium Treatment on Prefrontal and Subgenual Prefrontal Gray Matter Volume in Treatment-Responsive Bipolar Disorder Patients

(2009) Gregory J. Moore et al.   JOURNAL OF CLINICAL PSYCHIATRY

Rapid Enhancement of Glutamatergic Neurotransmission in Bipolar Depression Following Treatment with Riluzole

(2009) Brian P Brennan et al.   NEUROPSYCHOPHARMACOLOGY

Glutamate-mediated calcium signaling: A potential target for lithium action

(2009) N. Sourial-Bassillious et al.   NEUROSCIENCE

Ketamine and the next generation of antidepressants with a rapid onset of action

(2009) Rodrigo Machado-Vieira et al.   PHARMACOLOGY & THERAPEUTICS

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

(2009) L. J. Scott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of bipolar disorder: successful start to a long journey

(2009) Nick Craddock et al.   TRENDS IN GENETICS

A review of the preclinical and clinical evidence for protein kinase C as a target for drug development for bipolar disorder

(2009) Nancy DiazGranados et al.   Current Psychiatry Reports

Akt/GSK3 Signaling in the Action of Psychotropic Drugs

(2008) Jean-Martin Beaulieu et al.   Annual Review of Pharmacology and Toxicology

Meta-analysis, Database, and Meta-regression of 98 Structural Imaging Studies in Bipolar Disorder

(2008) Matthew J. Kempton et al.   ARCHIVES OF GENERAL PSYCHIATRY

Abnormal Glutamatergic Neurotransmission and Neuronal-Glial Interactions in Acute Mania

(2008) Dost Öngür et al.   BIOLOGICAL PSYCHIATRY

Evaluation of tissue collection for postmortem studies of bipolar disorder

(2008) Amy Deep-Soboslay et al.   BIPOLAR DISORDERS

Targeting Neurotrophin Receptors in the Central Nervous System

(2008) Italo Mocchetti et al.   CNS & Neurological Disorders-Drug Targets

The Biology of Neurotrophins, Signalling Pathways, and Functional Peptide Mimetics of Neurotrophins and their Receptors

(2008) Stephen Skaper   CNS & Neurological Disorders-Drug Targets

Brain-derived neurotrophic factor and neuroplasticity in bipolar disorder

(2008) Flavio Kapczinski et al.   Expert Review of Neurotherapeutics

Oxidative stress markers in bipolar disorder: A meta-analysis

(2008) Ana C. Andreazza et al.   JOURNAL OF AFFECTIVE DISORDERS

Glutamate receptors as targets of protein kinase C in the pathophysiology and treatment of animal models of Mania

(2008) Steven T. Szabo et al.   NEUROPHARMACOLOGY

Mitochondrially Mediated Plasticity in the Pathophysiology and Treatment of Bipolar Disorder

(2008) Jorge A Quiroz et al.   NEUROPSYCHOPHARMACOLOGY

Metabolic alterations in medication-free patients with bipolar disorder: A 3T CSF-corrected magnetic resonance spectroscopic imaging study

(2008) John D. Port et al.   PSYCHIATRY RESEARCH-NEUROIMAGING