Article
Immunology
Claire P. Mattison, Molly Dunn, Mary E. Wikswo, Anita Kambhampati, Laura Calderwood, Neha Balachandran, Eleanor Burnett, Aron J. Hall
Summary: Between 2009 and 2018, numerous gastroenteritis outbreaks were reported to the US National Outbreak Reporting System, with the majority attributed to person-to-person transmission in long-term care facilities, daycares, and schools. Investigations of norovirus-negative outbreaks should include testing for adenovirus, astrovirus, rotavirus, and sapovirus.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Biotechnology & Applied Microbiology
Bortagaray Viviana, Gamazo Pablo, Castro Sebastian, Grilli Marcos, Colina Rodney, Victoria Matias
Summary: This study estimates the risk of rotavirus and astrovirus infections for swimmers and fishers at Las Canas beach in Uruguay, and finds that fishers are at a higher risk of infection compared to swimmers.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Biology
Amanda de Oliveira Matos, Thais Cristina Vilela Rodrigues, Sandeep Tiwari, Pedro Henrique dos Santos Dantas, Geraldo Rodrigues Sartori, Vasco Ariston de Carvalho Azevedo, Joao Herminio Martins Da Silva, Siomar de Castro Soares, Marcelle Silva-Sales, Helioswilton Sales-Campos
Summary: Researchers developed a multi-epitope vaccine using immunoinformatics tools to prevent severe acute gastroenteritis caused by RV and NV. The vaccine contains multiple epitopes that are immunogenic and can induce a Th1 immune response, while being safe without allergenic or toxic regions.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Virology
Han Cao, Jinyuan Wu, Ning Luan, Yunfei Wang, Kangyang Lin, Cunbao Liu
Summary: The study found that NSP4 as an antigen in recombinant specific vaccines can provide strong protection, especially in rotavirus-induced diarrhea mouse models. However, its effect as an adjuvant in increasing neutralizing antibody production is limited.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Review
Immunology
Howard Faden, Beverly A. Schaefer
Summary: Histo-blood group antigen are receptors for norovirus and rotavirus, only present on the intestinal mucosal epithelial cells of secretors. Secretors are susceptible to these viruses, while nonsecretors are resistant. Secretor rates have evolved in response to environmental pressures such as infectious diseases.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Review
Biochemistry & Molecular Biology
Nazaret Pena-Gil, Cristina Santiso-Bellon, Roberto Gozalbo-Rovira, Javier Buesa, Vicente Monedero, Jesus Rodriguez-Diaz
Summary: Research has shown that histo-blood group antigens play a crucial role in norovirus and rotavirus infections, while the host's gut microbiota also influences the severity of enteric viral infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Gillian A. M. Tarr, Emily Downey, Xiao-Li Pang, Ran Zhuo, Ali J. Strickland, Samina Ali, Bonita E. Lee, Linda Chui, Phillip Tarr, Stephen B. Freedman
Summary: This study described and compared the clinical course of acute gastroenteritis in children with astrovirus, sapovirus, and norovirus infections. It found that astrovirus infections had a higher prevalence and longer duration of diarrhea compared to norovirus infections. Sapovirus infections were more similar to norovirus infections, but had a longer duration of vomiting.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Oncology
Gabriele Silva Souza Gois, Silmara Aparecida Lima Montalvao, Thaizy Ramires Alencar Anhaia, Millene Evelyn Alves Almeida, Beatriz Moraes Martinelli, Maria Carmen Goncalves Lopes Fernandes, Stephany Cares Hubers, Monique R. M. Ferreira, Daniel Dias Ribeiro, Julio Cesar Teixeira, Jose Barreto Campello Carvalheira, Carmen Silvia Passos Lima, Nelson Adami Andreollo, Mauricio Etchebehere, Lair Zambon, Ubirajara Ferreira, Alfio Jose Tincani, Antonio Santos Martins, Claudio Saddy Rodrigues Coy, Jose Claudio Teixeira Seabra, Ricardo Kalaf Mussi, Helder Tedeschi, Joyce Maria Anninchino-Bizzacchi
Summary: This study evaluated thrombin and plasmin generation in cancer patients and found an association between thrombin parameters and mortality risk. The findings can help identify high-risk cancer patients.
Article
Medical Laboratory Technology
Changhee Ha, In Young Yoo, Sun Ae Yun, Yoo Na Chung, Hee Jae Huh, Nam Yong Lee
Summary: The performance of AFIAS-Rota and AFIAS-Noro assays showed excellent agreement with the RIDASCREEN assays. While AFIAS-Noro exhibited lower sensitivity for detecting norovirus compared to RIDASCREEN Norovirus, the AFIAS assays had significantly shorter hands-on time and turnaround time, making them suitable for rapid initial screening in clinical laboratories.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2021)
Article
Food Science & Technology
M. Mozgovoj, S. Mino, E. S. Barbieri, F. L. Tort, M. Victoria-Montero, C. Frydman, M. Cap, P. J. Baron, R. Colina, J. Matthijnssens, V Parreno
Summary: This study found the presence of norovirus and rotavirus in Pacific cupped oysters from Argentina, with the rotavirus strain having a different genotype compared to those circulating in animal species in South America. The results highlight the need for surveillance programs to prevent potential foodborne viral outbreaks due to the consumption of contaminated shellfish.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2022)
Article
Medicine, General & Internal
Frederic Debellut, Kevin Tang, Andrew Clark, Clint Pecenka, Bachir Assao, Ousmane Guindo, Rebecca F. Grais, Sheila Isanaka
Summary: This study evaluates the cost-effectiveness of different rotavirus vaccines in Niger and suggests that ROTAVAC is likely the most cost-effective option. ROTAVAC can prevent a significant number of cases and child deaths while providing similar or higher benefits at a lower cost.
Article
Virology
Yuanyuan Qiu, Stephen B. Freedman, Sarah Williamson-Urquhart, Ken J. Farion, Serge Gouin, Naveen Poonai, Suzanne Schuh, Yaron Finkelstein, Jianling Xie, Bonita E. Lee, Linda Chui, Xiaoli Pang
Summary: Acute gastroenteritis (AGE) is a major cause of morbidity and mortality in children under 5 years of age worldwide. Norovirus, rotavirus, and enteric adenovirus are leading viral causes of pediatric AGE. This study found that norovirus had a significantly lower viral load compared to rotavirus and adenovirus on the day of enrollment, but had a higher viral load on days 5 and 28. Norovirus was detected in the stool for the longest duration compared to rotavirus and adenovirus.
Article
Infectious Diseases
Peter Pankovics, Akos Boros, Zoltan Laszlo, Sandor Szekeres, Gabor Foldvari, Eda Altan, Eric Delwart, Gabor Reuter
Summary: This study investigated viral infections in wild rats and laboratory rodents in different geographic areas of Hungary, identifying the presence of rat astrovirus, rat norovirus, and rat hepevirus among others. Co-infections were found in 28% of wild Norway rats, and the highest viral loads were measured in specific organs, highlighting the potential role of rodents in spreading viral pathogens to humans.
INFECTION GENETICS AND EVOLUTION
(2021)
Article
Engineering, Environmental
Marlee Shaffer, Kimberly Huynh, Veronica Costantini, Kyle Bibby, Jan Vinje
Summary: Human noroviruses are a major cause of acute gastroenteritis worldwide, but current environmental detection methods do not accurately assess the infectious risk.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2022)
Article
Immunology
Louisa Pollock, Aisleen Bennett, Khuzwayo C. Jere, Jonathan Mandolo, Queen Dube, Naor Bar-Zeev, Robert S. Heyderman, Nigel A. Cunliffe, Miren Iturriza-Gomara
Summary: Low plasma RV-specific IgA is strongly associated with rotavirus vaccine failure in Malawian infants. This study provides further evidence that RV-specific IgA is a marker of protection, although the question of reduced rotavirus vaccine efficacy in low-income countries remains unclear.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Immunology
Wang Wang, Wei-Zhen Liu, Zi-Liang Wang, Dong-Xiao Duan, Xue-Yun Wang, Shi-Jin Liu, Zhi-Ju Wang, Guo-Gang Xing, Ying Xing
Summary: This study used standard and modified social defeat stress mouse models to investigate the impact of perioperative social defeat stress on postsurgical pain in male and female mice. The results showed that social defeat stress could induce prolonged postsurgical pain, and spinal microglial activation plays a key role in this process in male mice. However, this effect was not significant in female mice.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Review
Pediatrics
Zijun Wang, Siya Zhao, Yuyi Tang, Zhili Wang, Qianling Shi, Xiangyang Dang, Lidan Gan, Shuai Peng, Weiguo Li, Qi Zhou, Qinyuan Li, Joy James Mafiana, Rafael Gonzalez Cortes, Zhengxiu Luo, Enmei Liu, Yaolong Chen
Summary: This systematic review evaluated the efficacy and safety of using potential drugs, remdesivir and glucocorticoid, in treating children and adolescents with COVID-19, as well as using intravenous immunoglobulin (IVIG) in treating MIS-C. The included studies showed that remdesivir may cause adverse events and death, while glucocorticoids were associated with mortality and mechanical ventilation rate. IVIG combined with methylprednisolone had better clinical efficacy for MIS-C patients with severe symptoms. The current evidence is of low quality, and high-quality randomized controlled trials are recommended to provide substantial evidence for guidelines development.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Environmental Sciences
Yiteng Zhang, Xingxing Cheng, Ziliang Wang, Mudassir Hussain Tahir, Zhiqiang Wang, Xuetao Wang, Chao Wang
Summary: This study proposed a novel multi-stage utilization process for cabbage waste, which involved low-temperature extraction, medium-temperature thermolysis, and high-temperature activation. The process yielded valuable products such as plant extracts, pyrolytic oil, and biochar, with optimized temperatures and performance characteristics.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biotechnology & Applied Microbiology
Siyu Song, Jing Wang, Guanwen Liu, Lu Ding, Yaxin Li, Hongyu Qi, Lai Wei, Jiachao Zhao, Tian Chen, Meiru Zhao, Ziyuan Wang, Yingying Yang, Daqing Zhao, Xiangyan Li, Zeyu Wang
Summary: In this study, the mechanism of the Wenfei Buqi Tongluo (WBT) formula in inhibiting inflammatory response during idiopathic pulmonary fibrosis (IPF) was explored. Network pharmacology and in vivo experiments were used to investigate the effects of the WBT formula. The results showed that the WBT formula can suppress IPF by inhibiting inflammation via the TLR4/MyD88/NF-kappa B pathway.
BIOMED RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Multidisciplinary
Qiangsheng Lu, Congcong Le, Xiaoqian Zhang, Jacob Cook, Xiaoqing He, Mohammad Zarenia, Mitchel Vaninger, Paul F. Miceli, David J. Singh, Chang Liu, Hailang Qin, Tai-Chang Chiang, Ching-Kai Chiu, Giovanni Vignale, Guang Bian
Summary: This study proposes a new method to achieve flat band physics in monolayer graphene by substrate modulation. Experimental results on the graphene/SiC heterostructure demonstrate that substrate modulation leads to Dirac fermion cloning and the proximity of the two Dirac cones in monolayer graphene. Theoretical modeling confirms the cloning mechanism and predicts the emergence of moire flat bands at certain magic lattice constants of the substrate. This study suggests that epitaxial single monolayer graphene on suitable substrates is a promising platform for exploring exotic many-body quantum phases arising from interactions between Dirac electrons.
ADVANCED MATERIALS
(2022)
Article
Biotechnology & Applied Microbiology
Jun Bai, Yanxi Liu, Mengjiao Liu, Shiting Luo, Yuhong Cheng, Gang Li, Cheng Liu, Shixiong Wen, Mian Xia, Xiaoqing He, Yi Jin
Summary: This study investigated the potential application of a phage cocktail in controlling Pseudomonas syringae pv. actinidiae (Psa) infection, and the results showed better biological treatment efficacy of the phage cocktail compared to individual phages.
BIOLOGICAL CONTROL
(2022)
Article
Immunology
Xiaoqing He, Yifu Liu, Haoyu Wang, Wei Sun, Yihan Lu, Zhongyan Shan, Weiping Teng, Jing Li
Summary: The highly expressed ENO1-P6 autoantibodies may be important risk factors for miscarriage in euthyroid females with thyroid autoimmunity. The levels of ENO1-P6 autoantibodies in the serum may serve as good predictive markers for pregnancy loss in euthyroid females with thyroid autoimmunity, especially the expression of its IgG2 subclass.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Ganggang Zhao, Yun Ling, Yajuan Su, Zanyu Chen, Cherian J. Mathai, Ogheneobarome Emeje, Alexander Brown, Dinesh Reddy Alla, Jie Huang, Chansong Kim, Qian Chen, Xiaoqing He, David Stalla, Yadong Xu, Zehua Chen, Pai-Yen Chen, Shubhra Gangopadhyay, Jingwei Xie, Zheng Yan
Summary: Laser scribing of metallic conductive transition metal oxides on soft elastomers has been achieved, with high electrical conductivity, biocompatibility, chemical stability, and compatibility with magnetic resonance imaging. This method shows potential for constructing bioelectronics and soft actuators.
Article
Materials Science, Multidisciplinary
Ahmed Al Mayyahi, Swagotom Sarker, Brian M. Everhart, Xiaoqing He, Placidus B. Amama
Summary: In this study, delaminated and OH-terminated MXene was synthesized through a one-step hydrothermal process. The co-catalytic effect of this MXene combined with TiO2 was found to be highly effective in photocatalytic oxidation of NOx. The OH-terminated MXene outperformed the F-terminated MXene in terms of NO2 storage selectivity and DeNOx index.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Behavioral Sciences
Lin Zhao, Dongdong Zhou, Lingli Ma, Jinhui Hu, Ran Chen, Xiaoqing He, Xinyu Peng, Zhenghao Jiang, Liuyi Ran, Jiaojiao Xiang, Qi Zeng, Yi Zhou, Linxi Dai, Qi Zhang, Su Hong, Wo Wang, Li Kuang
Summary: Nonsuicidal self-injury (NSSI) is a serious risk behavior in adolescents and is strongly associated with suicide. This study examined the behavioral and neural responses in adolescents with NSSI when exposed to negative emotional stimuli using a two-choice oddball paradigm. The results showed that adolescents with NSSI exhibited distinct neural responses, specifically in the N250, P300, and LPP components, during negative emotional face stimulation. Additionally, the study found evidence of brain lateralization effects in both the N250 and LPP components.
BEHAVIOURAL BRAIN RESEARCH
(2023)
Article
Geochemistry & Geophysics
Xiaoqing He, Ziyao Fang, Yunpei Gao, Xi Yu, Yanan Shen, Liping Qin
Summary: The redox states of the ocean and atmosphere during the Ediacaran Period remain controversial. This study presents systematic Cr isotopic data for two Ediacaran successions in South China, revealing that the ocean redox conditions were highly stratified and heterogeneous. The positively fractionated 853Cr values indicate higher atmospheric oxygen and enhanced biological productivity during this period.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Jiahui Guo, Yihan Lu, Xiaoqing He, Jiashu Li, Chenling Fan, Hongmei Zhang, Weiping Teng, Zhongyan Shan, Jing Li
Summary: Our recent study found that ENO1Ab expression in an experimental AIT mouse model was induced by thyroglobulin (Tg) immunization. In this study, we investigated the potential roles of ENO1Ab in miscarriage occurrence among AIT women and the specific epitopes of ENO1 targeted by ENO1Ab. The results showed that serum ENO1Ab was an independent risk factor for miscarriage, especially among AIT females, and the autoantibody specific to the P6 epitope of ENO1 may be more specifically related to this disorder.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Psychiatry
Lin Zhao, Dongdong Zhou, Jinhui Hu, Xiaoqing He, Xinyu Peng, Lingli Ma, Xinyi Liu, Wanqing Tao, Ran Chen, Zhenghao Jiang, Chenyu Zhang, Jing Liao, Jiaojiao Xiang, Qi Zeng, Linxi Dai, Qi Zhang, Su Hong, Wo Wang, Li Kuang
Summary: In this study, changes in microstate parameters in depressed adolescents with nonsuicidal self-injury (NSSI), depressed adolescents, and healthy adolescents during exposure to negative emotional stimuli were compared. The effects of repetitive transcranial magnetic stimulation (rTMS) on clinical symptoms and microstate parameters were also explored in depressed adolescents with NSSI. The findings provide evidence for potential mechanisms and treatment optimization for NSSI behaviors in adolescents.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Biotechnology & Applied Microbiology
Chenwu Xiong, Hua Tong, Xiaoqing He, Dewu Ding
Summary: In this study, we integrated the transcriptome changes of Shewanella oneidensis MR-1 under different oxygen levels into its protein-protein interaction network to investigate the specific changes under these conditions. The results showed that most of the key nodes in the network were ribosomes or proteins closely related to ribosomes under high and low oxygen levels. Additionally, we analyzed the changes in protein-protein interactions and identified key interactions in three pairs of active networks. This study provides guidance for identifying key proteins and interactions under different conditions for this species.
ANNALS OF MICROBIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Zhenkun Wang, Aihua Du, Hong Liu, Ziwei Wang, Jifa Hu
Summary: This study investigates the temporal and regional trends, as well as risk factors, of cardiovascular diseases (CVDs) worldwide from 1990 to 2017. The study finds that the number of deaths from CVDs has increased over time, but the age-standardized mortality rate has decreased. Metabolic risks and behavioral factors are identified as the main contributors to CVDs.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2022)