Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

Rapid-onset clinical and mechanistic effects of anti-C5aR treatment in the mouse collagen-induced arthritis model

(2014) C. Andersson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Homeostatic Regulation of Blood Neutrophil Counts

(2014) S. von Vietinghoff et al.   JOURNAL OF IMMUNOLOGY

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation

(2013) Markus Bosmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts

(2013) Salahuddin Ahmed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Single Functional Group Substitution in C5a Breaks B Cell and T Cell Tolerance and Protects Against Experimental Arthritis

(2013) Christoph Kessel et al.   Arthritis & Rheumatology

Interactions of the complement system with molecules of extracellular matrix: Relevance for joint diseases

(2012) Kaisa E. Happonen et al.   IMMUNOBIOLOGY

Complement in the immunopathogenesis of rheumatic disease

(2012) Gunnar Sturfelt et al.   Nature Reviews Rheumatology

New developments in osteoimmunology

(2012) Hiroshi Takayanagi   Nature Reviews Rheumatology

Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and Fc R signaling

(2012) C. D. Sadik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice

(2012) Sara M Atkinson et al.   ARTHRITIS RESEARCH & THERAPY

Complement Activation Triggers Metalloproteinases Release Inducing Cervical Remodeling and Preterm Birth in Mice

(2011) Juan M. Gonzalez et al.   AMERICAN JOURNAL OF PATHOLOGY

Novel roles of complement in T effector cell regulation

(2011) Peter S. Heeger et al.   IMMUNOBIOLOGY

The new face of anaphylatoxins in immune regulation

(2011) Wuding Zhou   IMMUNOBIOLOGY

Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β

(2011) Anita Ignatius et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of C3a Receptors, C5a Receptors, and Complement Protein C6 Deficiency in Collagen Antibody-Induced Arthritis in Mice

(2011) N. K. Banda et al.   JOURNAL OF IMMUNOLOGY

Neutrophils in a mouse model of autoantibody-mediated arthritis: Critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function−associated antigen 1

(2010) Paul A. Monach et al.   ARTHRITIS AND RHEUMATISM

Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis

(2010) Cheng-Chi Chao et al.   AUTOIMMUNITY

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis

(2010) Richard C. Chou et al.   IMMUNITY

Complement drives Th17 cell differentiation and triggers autoimmune arthritis

(2010) Motomu Hashimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-1 pathways in inflammation and human diseases

(2010) Cem Gabay et al.   Nature Reviews Rheumatology

Angiogenesis in rheumatoid arthritis

(2009) Zoltán Szekanecz et al.   AUTOIMMUNITY

The complement system in systemic autoimmune disease

(2009) Min Chen et al.   JOURNAL OF AUTOIMMUNITY

Proinflammatory Role of Vascular Endothelial Growth Factor in the Pathogenesis of Rheumatoid Arthritis: Prospects for Therapeutic Intervention

(2009) Seung-Ah Yoo et al.   MEDIATORS OF INFLAMMATION

CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis

(2008) Renata Grespan et al.   ARTHRITIS AND RHEUMATISM

Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis

(2008) P. N. Lalli et al.   BLOOD

Locally Produced Complement Fragments C5a and C3a Provide Both Costimulatory and Survival Signals to Naive CD4+ T Cells

(2008) Michael G. Strainic et al.   IMMUNITY