Article
Biochemical Research Methods
Pablo Artal, Harilaos Ginis, Dimitrios Christaras, Eloy A. Villegas, Juan Tabernero, Pedro M. Prieto
Summary: Current intraocular lenses (IOLs) focus on replacing the cataractous crystalline lens, but their common biconvex design neglects off-axis performance, resulting in reduced optical quality in the periphery of the retina. To address this, a concave-convex inverted meniscus IOL with aspheric surfaces was designed using ray-tracing simulations. The new IOL showed superior image quality throughout the visual field compared to the standard thin biconvex lenses commonly used, making it a better substitute for the natural lens.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Ophthalmology
Ding Han, Ziyu Zhang, Bingqin Li, Hua Rong, Desheng Song, Bei Du, Ruihua Wei
Summary: Concentric dual-focus-designed contact lenses provide satisfactory distance visual acuity in myopic Chinese individuals, but decreased contrast sensitivity and increased higher-order aberrations at higher spatial frequencies may result in poorer visual performance.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Chemistry, Analytical
Uriel Calderon-Uribe, Geovanni Hernandez-Gomez, Armando Gomez-Vieyra
Summary: A study presents an objective technique to measure longitudinal chromatic aberration (LCA) on the last crystalline lens surface using a pulse width wavefront system with a Hartmann test, Purkinje image, and Zernike polynomial. Blue and red pulses can generate a pattern on the human eye, allowing the reconstruction of the wavefront to quantify LCA using Zernike coefficients. The methodology and objective measurements of LCA of five test subjects are explained in the article.
Article
Ophthalmology
Bianca Maceo Heilman, Ashik Mohamed, Marco Ruggeri, Siobhan Williams, Arthur Ho, Jean-Marie Parel, Fabrice Manns
Summary: The research characterized the peripheral defocus of isolated human crystalline lenses and its age dependence. The findings showed that lens power decreased with age, increased with delivery angle, indicating a shift towards myopic peripheral defocus. The relative peripheral defocus of the lenses also decreased with age.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
Qi Tan, Pauline Cho, Alex L. K. Ng, George P. M. Cheng, Victor C. P. Woo, Stephen J. J. Vincent
Summary: This study evaluated the retinal image quality in children undergoing combined atropine and orthokeratology treatment (AOK) compared to those receiving orthokeratology alone (OK). The study found that the AOK group had lower retinal image quality based on higher-order aberrations (HOA) compared to the OK group under photopic conditions. However, overall retinal image quality based on both lower-order aberrations (LOA) and HOA was similar between the two groups.
Article
Chemistry, Multidisciplinary
Najnin Sharmin, Petros Papadogiannis, Dmitry Romashchenko, Linda Lundstrom, Brian Vohnsen
Summary: The accommodative response of the human eye is predominantly driven by foveal vision but also reacts to off-foveal stimuli. This study measured monocular accommodation using annular stimuli centered around the fovea and extending to different radial eccentricities. The results showed a significant reduction in accommodative response with increased radial eccentricity.
APPLIED SCIENCES-BASEL
(2023)
Article
Medicine, General & Internal
Xi-Fang Zhang, Xiao-Xia Li, Chen Xin, Brad Kline, Meng-Tian Kang, Meng Li, Li-Ya Qiao, Ning-Li Wang
Summary: This study highlights the importance of an objective method to evaluate the severity of partial cataracts in early-onset high myopia patients. The analysis of clinical characteristics and retinal image quality before and after refractive lens replacement surgery showed that the surgery is safe and effective in improving visual function.
FRONTIERS IN MEDICINE
(2022)
Article
Optics
Jakub Belin, Johannes Courtial, Tomas Tyc
Summary: Lens stars are composed of identical thin lenses arranged in a regular star shape, suitable for building ideal-lens TO devices. Ray trajectories in lens stars are found to be piecewise straight approximations of conic sections, and the concept is extended to Platonic lenses for further study. The research contributes to the understanding of TO with ideal lenses.
Article
Ophthalmology
Zengying Wang, Yifei Meng, Zuocheng Wang, Lili Hao, Vania Rashidi, Haiyan Sun, Jun Zhang, Xiaokun Liu, Xuemin Duan, Zhaocai Jiao, Sufang Qie, Zhipeng Yan
Summary: This study aimed to investigate the ocular measurements associated with axial length (AL) growth in children wearing ortho-k lenses. The results showed that both crystalline lens thickness (CLT) and AL significantly increased after 12 months of ortho-k wear. Greater baseline spherical equivalent (SE) and greater increase in CLT were associated with less increase in AL during ortho-k wear in children with myopia.
CONTACT LENS & ANTERIOR EYE
(2022)
Article
Ophthalmology
Len Zheleznyak
Summary: This study investigates the impact of refractive error on peripheral image quality. Peripheral blur orientation is determined by optical aberrations and retinal shape. Peripheral blur anisotropy can play a role in accommodation, emmetropisation, and myopia control interventions. The study finds that different refractive errors result in variations in through-focus optical anisotropy and image quality, with myopes exhibiting vertically elongated blur, while emmetropes and hyperopes exhibit horizontally elongated blur.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Rohan P. J. Hughes, Scott A. Read, Michael J. Collins, Stephen J. Vincent
Summary: This study investigates the changes in higher order aberrations and retinal image quality during accommodation in children with different refractive errors. The results show that near work has a greater impact on myopic children, while non-myopic children show greater changes in spherical aberration during accommodation.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Medicine, General & Internal
Adeline Yang, Si Ying Lim, Yee Ling Wong, Anna Yeo, Narayanan Rajeev, Bjorn Drobe
Summary: This study showed that highly myopic presbyopes had worse overall quality of life and functionality compared to presbyopes with low myopia. However, the use of PAL lenses improved perception outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Zhe Zhang, Zhi Chen, Jiaqi Zhou, Jaume Paune, Feng Xue, Li Zeng, Xiaomei Qu, Xingtao Zhou
Summary: This study found that orthokeratology lenses with smaller back optic zone diameter design may lead to faster myopic reduction and a smaller aspheric treatment zone.
OPTOMETRY AND VISION SCIENCE
(2022)
Article
Ophthalmology
Rohit Saxena, Vinay Gupta, Rebika Dhiman, Swati Phuljhele, Pawan Kumar, Namrata Sharma, Rafael Iribarren, Jos Rozema
Summary: This nonrandomized clinical trial evaluated the change in crystalline lens power (LP) in a cohort of Indian children with progressive myopia receiving atropine (0.01%) treatment. The results showed that children treated with atropine had less myopia progression and greater loss of LP, indicating a potential relationship between the therapeutic effect of atropine and changes in LP.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Eloy A. Villegas, Jose M. Marin, Harilaos Ginis, Consuelo Robles, Encarna Alcon, Lucia Hervella, Pedro M. Prieto, Pedro Tana-Rivero, Pablo Artal
Summary: Pseudophakic patients with a new type of inverted meniscus intraocular lens (IOL) show improved contrast detection sensitivity in the periphery due to reduced defocus and astigmatism compared to patients with standard biconvex IOLs.
JOURNAL OF REFRACTIVE SURGERY
(2022)
Article
Ophthalmology
Shuyu Xiong, Xiangui He, Padmaja Sankaridurg, Jianfeng Zhu, Jingjing Wang, Bo Zhang, Haidong Zou, Xun Xu
Summary: The study found that there is accelerated loss of lens power in emmetropia and early stage of myopia. However, this loss is retarded when myopia persists and is accompanied by disappearance of the compensatory effect of lens power against axial elongation.
ACTA OPHTHALMOLOGICA
(2022)
Article
Ophthalmology
Xiangui He, Padmaja Sankaridurg, Thomas Naduvilath, Jingjing Wang, Shuyu Xiong, Rebecca Weng, Linlin Du, Jun Chen, Haidong Zou, Xun Xu
Summary: This study developed age-specific and gender-specific reference percentile charts for axial length (AL) and AL/corneal radius of curvature (AL/CR), which can be used to determine probability of myopia, estimate refractive error (RE), and identify and monitor individuals at risk of myopia. The accuracy of these percentile charts was validated using an independent sample of children's eyes. The results showed a high concordance between the estimated and actual measurements.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Letter
Ophthalmology
Thomas Naduvilath, Padmaja Sankaridurg
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Krupa Philip, Padmaja Sankaridurg, Thomas Naduvilath, Nagaraju Konda, Kalika Bandamwar, Swathi Kanduri, Jaya Sowjanya Siddireddy
Summary: This study investigated the prevalence of refractive errors and associated risk factors in children and young adults from the urban region of Hyderabad, South India. The results showed that myopia was the most common refractive error, with a higher prevalence in lower socio-economic category schools.
OPHTHALMIC EPIDEMIOLOGY
(2023)
Review
Ophthalmology
Tim R. Fricke, Padmaja Sankaridurg, Thomas Naduvilath, Serge Resnikoff, Nina Tahhan, Mingguang He, Kevin D. Frick
Summary: This study describes a methodology for estimating lifetime myopia costs and compares different management options in the context of Australia and China. The results suggest that investing in active myopia management can lead to economic balance or even better outcomes by reducing refractive progression, using simpler lenses, and minimizing the risk of pathology and vision loss.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Xiangui He, Padmaja Sankaridurg, Jingjing Wang, Jun Chen, Thomas Naduvilath, Mingguang He, Zhuoting Zhu, Wayne Li, Ian G. Morgan, Shuyu Xiong, Jianfeng Zhu, Haidong Zou, Kathryn A. Rose, Bo Zhang, Rebecca Weng, Serge Resnikoff, Xun Xu
Summary: The study aimed to evaluate the efficacy of time spent outdoors per school day on myopia onset and shift. The results showed that increasing outdoor time reduced the risk of myopia, especially in nonmyopic children. The protective effect was related to the duration of exposure and light intensity.
Article
Ophthalmology
Padmaja Sankaridurg, Rebecca Weng, Huy Tran, Daniel P. Spiegel, Bjorn Drobe, Thao Ha, Yen H. Tran, Thomas Naduvilath
Summary: This study compared highly aspherical lenslet (HAL) spectacles with conventional single vision (SV) spectacles to evaluate myopia progression. The results showed that HAL slowed down myopia progression compared to SV at different stages, and there was no rebound effect when switching from HAL to SV.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jingjing Wang, Padmaja Sankaridurg, Thomas Naduvilath, Wayne Li, Ian G. Morgan, Kathryn A. Rose, Rebecca Weng, Xun Xu, Xiangui He
Summary: This study investigates the relationship between outdoor time and academic performance among school-aged children. It found that outdoor time and sleep duration were non-linearly associated with academic performance, suggesting that promoting outdoor time may not have a negative impact on academic performance.
Article
Ophthalmology
Thomas Naduvilath, Xiangui He, Xun Xu, Padmaja Sankaridurg
Summary: This study aimed to investigate the impact of refractive error, age, gender, and parental myopia on axial elongation in Chinese children and provide normative data for the population. The results showed that axial elongation decreased with age, with different effects depending on the refractive error group. Myopic children had higher axial elongation compared to emmetropic and hyperopic children, but these differences decreased as they grew older.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Padmaja Sankaridurg, David A. Berntsen, Mark A. Bullimore, Pauline Cho, Ian Flitcroft, Timothy J. Gawne, Kate L. Gifford, Monica Jong, Pauline Kang, Lisa A. Ostrin, Jacinto Santodomingo-Rubido, Christine Wildsoet, James S. Wolffsohn
Summary: Myopia is a complex and evolving field, with ongoing research providing new insights and strategies for myopia control. The International Myopia Institute (IMI) has published white papers and updated evidence, summarizing key findings from the past two years. Studies in animal models have explored the influence of light on eye growth and potential treatments for myopia. In children, the concept of premyopia and early myopia control implementation is gaining attention. Various clinical trials have demonstrated the efficacy and safety of different treatments, such as spectacle lens designs, contact lenses, and pharmaceutical options. The ethics of including control arms in clinical trials and the IMI recommendations for trial protocols are also discussed.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Meeting Abstract
Ophthalmology
Rebecca Weng, Huy Dinh Minh Tran, Daniel P. Spiegel, Bjorn Drobe, Thomas John Naduvilath, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Padmaja Sankaridurg, Huy Dinh Minh Tran, Thomas John Naduvilath, Thao Ha, Tuan Diep Tran, Krupa Philip, Rebecca Weng, Minas Coroneo, Yen Hai Tran
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Dean Psarakis, Craig Woods, Thomas John Naduvilath, Nina Tahhan, Senuri Karunaratne, Divya Jagadeesh, Arthur Back, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Xiao Nicole Liu, Thomas John Naduvilath, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Huy Dinh Minh Tran, Yen Hai Tran, Thao Ha, Tuan Diep Tran, Thomas John Naduvilath, Krupa Philip, Rebecca Weng, Monica Jong, Minas Coroneo, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Article
Neurosciences
Ryan P. Silk, Hanagh R. Winter, Ouria Dkhissi-Benyahya, Carmella Evans -Molina, Alan W. Stitt, Vijay K. Tiwari, David A. Simpson, Eleni Beli
Summary: This study investigates whether diabetes affects the daily rhythm of gene expression in the retina. The results show that diabetic mice exhibited phase advancement in the expression of certain genes compared to non-diabetic mice. The study also identified oxygen-sensing mechanisms and HIF1alpha as potential upstream regulators. These findings provide important insights into the development of diabetic retinopathy.
Article
Neurosciences
Krishnamachari S. Prahalad, Daniel R. Coates
Summary: Visual stimuli presented around the time of a saccade can be perceived differently by the visual system, including a reduction in the harmful impact of flankers. This study investigated the effects of microsaccades on crowded stimuli placed 20 arc minutes from the center of gaze. The findings suggest two separate pre-saccadic benefits, one that regularizes the crowding zone and another that specifically benefits microsaccade targets surrounded by tangential flankers.
Article
Neurosciences
Chandrika Ravisankar, Christopher W. Tyler, Clifton M. Schor, Shrikant R. Bharadwaj
Summary: This study revealed that less than one-third of adults with normal binocular vision were able to successfully free-fuse random-dot image pairs and identify the embedded stereoscopic shapes. The successful participants showed a dissociation of vergence and accommodative responses, while the unsuccessful ones either exhibited strong vergence and accommodation or weak vergence and strong accommodation. Task performance of the unsuccessful cluster improved significantly with pharmacological paralysis of accommodation. A minority of participants also learned to dissociate one direction of their vergence and accommodation crosslinks with repeated free-fusion trials, optimizing their task performance.