Article
Medicine, General & Internal
Jiahui Chen, Yating Tang, Qinghe Jing, Yi Lu, Yongxiang Jiang
Summary: The study analyzed the corneal spherical aberrations in patients with Chinese bilateral ectopia lentis, finding that the values were significantly lower in Marfan syndrome patients compared to non-Marfan syndrome patients, and tended to increase with aging. Individual measurement of corneal spherical aberration was necessary for bilateral ectopia lentis patients, especially those with Marfan syndrome.
FRONTIERS IN MEDICINE
(2021)
Article
Medicine, General & Internal
Xiaochun Li, Xiaoguang Cao, Xian-Ru Hou, Li Yuan, Ying-Ying Yu, Yong-Zhen Bao
Summary: This study investigated the effect of transparent corneal incision (TCI) and scleral tunnel incision (STI) on corneal spherical aberration (CSA) after cataract phacoemulsification. The results suggested that TCI may increase postoperative CSA compared to STI.
Article
Multidisciplinary Sciences
Jian Lin
Summary: The study found that the magnitude of ocular residual astigmatism is relatively small in children's astigmatic eyes, mainly in against-the-rule and oblique astigmatism. Most of the ORA can counteract ACA, while a small portion superimposed it. Both against-the-rule and oblique ORA can counteract with-the-rule ACA.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Dandan Wang, Chunlu Liu, Weichen Guan, Ziyi Lu, Yinying Zhao, Yune Zhao
Summary: The purpose of this study was to investigate the impact of corneal spherical aberration on the visual acuity and quality of eyes implanted with the TECNIS Symfony intraocular lens. The results showed that postoperative near vision was better, and preoperative corneal spherical aberration was negatively correlated with postoperative near vision and glare contrast sensitivity. Postoperative ocular spherical aberration was not correlated with visual acuity, contrast sensitivity, and visual quality.
FRONTIERS IN MEDICINE
(2023)
Article
Ophthalmology
So Goto, Naoyuki Maeda
Summary: Corneal topography is useful in selecting premium intraocular lenses (IOLs) for refractive cataract surgery, as it helps identify corneal irregularities and assists in predicting postoperative visual outcomes. By analyzing corneal shape abnormalities and astigmatism, surgeons can make informed decisions about the suitability of different types of IOLs for each patient, ultimately improving surgical outcomes and patient satisfaction.
Article
Ophthalmology
Fei Yang, Yongzhen Bao
Summary: This study investigated the distribution of corneal spherical aberration (CSA) and its relationship with corneal curvature and anterior chamber parameters. The results showed that corneal curvature was positively correlated with anterior chamber depth (ACD), and anterior chamber volume (ACV) and anterior chamber angle (ACA) were relatively stable in different corneal curvatures. These findings are important for understanding the characteristics of corneal spherical aberration and its influencing factors.
OPHTHALMOLOGY AND THERAPY
(2023)
Article
Ophthalmology
Shikha Gupta, Karthikeyan Mahalingam, Arjun Desai, Ananya Kaginalkar, Mayank Bhardwaj, Abhishek Singh, Viney Gupta
Summary: This study found that patients with PCG had significantly higher ocular higher order and lower order aberrations, which could have a negative impact on visual function. These findings are important for the management of visual rehabilitation in PCG patients.
CURRENT EYE RESEARCH
(2022)
Article
Ophthalmology
Noel Alpins, James K. Y. Ong, J. Bradley Randleman, George Stamatelatos
Summary: The purpose of this study is to determine the optimal corneal regions for deriving corneal topographic astigmatism (CorT) in keratoconic eyes. Possible measures of corneal astigmatism are calculated from raw total corneal power data and evaluated based on the variability of ocular residual astigmatism (ORA). It is found that corneal astigmatism measures derived from regions centered on the corneal vertex or 30% towards the thinnest point from the corneal vertex have lower variability.
JOURNAL OF REFRACTIVE SURGERY
(2023)
Article
Ophthalmology
Noel Alpins, James K. Y. Ong, J. Bradley Randleman, George Stamatelatos
Summary: The purpose of this study is to determine the optimal corneal regions for calculating corneal topographic astigmatism (CorT) in keratoconic eyes. The study found that the corneal astigmatism measures derived from regions centered on the corneal vertex corresponded more closely to the manifest refractive cylinder compared to measures derived from other regions, especially in mild keratoconus. However, none of the corneal astigmatism measures closely corresponded to the manifest refractive cylinder in severe keratoconus.
JOURNAL OF REFRACTIVE SURGERY
(2023)
Article
Ophthalmology
Hassan Hashemi, Shima Mesbahi, Alireza Jamali, Hadi Ostadimoghaddam, Abbasali Yekta, Mehdi Khabazkhoob
Summary: This study investigates the relationship between ocular biometric components and corneal higher-order aberrations in an elderly population. The findings suggest that these components play a significant role in interpreting the characteristics of images formed on the retina, highlighting the importance of considering them in medical and surgical procedures for the elderly.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Biochemical Research Methods
Carmen M. Lago, Alberto De Castro, Clara Benedi-Garia, Sara Aissati, Susana Marcos
Summary: Adaptive optics (AO) visual simulators are excellent platforms for non-invasive simulation visual performance with new intraocular lens (IOL) designs. Researchers measured the through focus visual acuity in subjects with a new refractive IOL physically inserted in a cuvette and projected onto the eye's pupil. The IOL increased depth-of-focus (DOF) while maintaining high visual acuity.
BIOMEDICAL OPTICS EXPRESS
(2022)
Article
Ophthalmology
Andrea Russo, Ottavia Filini, Chiara Salvalai, Alessandro Boldini, Giulia Festa, Luisa Delcassi, Francesco Morescalchi, Francesco Semeraro
Summary: This study analyzed the changes in corneal spherical aberration following PRK and LASIK surgeries, finding that LASIK induced more spherical aberration compared to PRK, and the beneficial effect of WFG treatment on spherical aberration was mainly visible in PRK-treated eyes.
OPHTHALMOLOGY AND THERAPY
(2021)
Article
Ophthalmology
Fangyu Lin, Xinjie Mao, Lirong Ma, Huiying Liu
Summary: A new ocular nebulization therapy combined with meibomian gland massage for MGD treatment showed better improvement in tear meniscus height and first breakup time compared to the eye drop group. Both groups had improvements in corneal fluorescein staining and Schirmer I test results. After 3 months, anterior corneal trefoil aberrations decreased significantly in the nebulization group, while improvements in anterior corneal coma aberrations and posterior corneal higher-order aberrations were observed in the eye drop group.
ACTA OPHTHALMOLOGICA
(2022)
Article
Ophthalmology
Rahul Deshpande, Anuj Satijia, Kuldeep Dole, Varsha Mangiraj, Madan Deshpande
Summary: This study compared the effects of implanting spherical and aspheric foldable intraocular lenses on postoperative visual quality, spherical aberration, and contrast sensitivity. The results showed that aspheric lenses reduced spherical aberration and improved contrast sensitivity.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Kepa Balparda, Maria Isabel Maya-Naranjo, Sara Mesa-Mesa, Tatiana Herrera-Chalarca
Summary: The study aimed to evaluate the effect of different corneal and whole-eye higher order aberrations (HOAs) on levels of ocular residual astigmatism (ORA). The results showed that general corneal irregularity, especially regular astigmatism, was associated with an increase in ORA, but corneal and whole-eye HOAs were not significantly correlated with ORA.
Article
Ophthalmology
Shuyu Xiong, Xiangui He, Padmaja Sankaridurg, Jianfeng Zhu, Jingjing Wang, Bo Zhang, Haidong Zou, Xun Xu
Summary: The study found that there is accelerated loss of lens power in emmetropia and early stage of myopia. However, this loss is retarded when myopia persists and is accompanied by disappearance of the compensatory effect of lens power against axial elongation.
ACTA OPHTHALMOLOGICA
(2022)
Article
Ophthalmology
Xiangui He, Padmaja Sankaridurg, Thomas Naduvilath, Jingjing Wang, Shuyu Xiong, Rebecca Weng, Linlin Du, Jun Chen, Haidong Zou, Xun Xu
Summary: This study developed age-specific and gender-specific reference percentile charts for axial length (AL) and AL/corneal radius of curvature (AL/CR), which can be used to determine probability of myopia, estimate refractive error (RE), and identify and monitor individuals at risk of myopia. The accuracy of these percentile charts was validated using an independent sample of children's eyes. The results showed a high concordance between the estimated and actual measurements.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Krupa Philip, Padmaja Sankaridurg, Thomas Naduvilath, Nagaraju Konda, Kalika Bandamwar, Swathi Kanduri, Jaya Sowjanya Siddireddy
Summary: This study investigated the prevalence of refractive errors and associated risk factors in children and young adults from the urban region of Hyderabad, South India. The results showed that myopia was the most common refractive error, with a higher prevalence in lower socio-economic category schools.
OPHTHALMIC EPIDEMIOLOGY
(2023)
Review
Ophthalmology
Tim R. Fricke, Padmaja Sankaridurg, Thomas Naduvilath, Serge Resnikoff, Nina Tahhan, Mingguang He, Kevin D. Frick
Summary: This study describes a methodology for estimating lifetime myopia costs and compares different management options in the context of Australia and China. The results suggest that investing in active myopia management can lead to economic balance or even better outcomes by reducing refractive progression, using simpler lenses, and minimizing the risk of pathology and vision loss.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Rebecca Weng, Weizhong Lan, Ravi Bakaraju, Fabian Conrad, Thomas Naduvilath, Zhi-kuan Yang, Padmaja Sankaridurg
Summary: This study compared the efficacy of two myopia control contact lenses with a single-vision contact lens. The results showed that the extended depth of focus and MiSight (R) contact lenses demonstrated similar effectiveness in slowing myopia progression. When switched to a single-vision contact lens, myopia progression was similar to age-matched wearers in single-vision contact lenses and did not indicate rebound.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Padmaja Sankaridurg, Rebecca Weng, Huy Tran, Daniel P. Spiegel, Bjorn Drobe, Thao Ha, Yen H. Tran, Thomas Naduvilath
Summary: This study compared highly aspherical lenslet (HAL) spectacles with conventional single vision (SV) spectacles to evaluate myopia progression. The results showed that HAL slowed down myopia progression compared to SV at different stages, and there was no rebound effect when switching from HAL to SV.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jingjing Wang, Padmaja Sankaridurg, Thomas Naduvilath, Wayne Li, Ian G. Morgan, Kathryn A. Rose, Rebecca Weng, Xun Xu, Xiangui He
Summary: This study investigates the relationship between outdoor time and academic performance among school-aged children. It found that outdoor time and sleep duration were non-linearly associated with academic performance, suggesting that promoting outdoor time may not have a negative impact on academic performance.
Article
Ophthalmology
Tianni Jia, Daniel Tilia, Fiona Stapleton, Eric Papas, Yi Zhen, Fabian Conrad, Jacqueline Tan
Summary: This study examined whether refraction and spectacle prescription using 0.05D-steps can improve the proportion of eyes achieving duochrome equality and provide better visual outcomes compared to 0.25D-steps. The results showed that refraction and spectacle prescription using 0.05D-steps led to a higher proportion of eyes achieving duochrome equality and better visual outcomes in various acuity-based measurements. Participants also expressed a preference for spectacles in 0.05D-steps.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Ophthalmology
Thomas Naduvilath, Xiangui He, Xun Xu, Padmaja Sankaridurg
Summary: This study aimed to investigate the impact of refractive error, age, gender, and parental myopia on axial elongation in Chinese children and provide normative data for the population. The results showed that axial elongation decreased with age, with different effects depending on the refractive error group. Myopic children had higher axial elongation compared to emmetropic and hyperopic children, but these differences decreased as they grew older.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Padmaja Sankaridurg, David A. Berntsen, Mark A. Bullimore, Pauline Cho, Ian Flitcroft, Timothy J. Gawne, Kate L. Gifford, Monica Jong, Pauline Kang, Lisa A. Ostrin, Jacinto Santodomingo-Rubido, Christine Wildsoet, James S. Wolffsohn
Summary: Myopia is a complex and evolving field, with ongoing research providing new insights and strategies for myopia control. The International Myopia Institute (IMI) has published white papers and updated evidence, summarizing key findings from the past two years. Studies in animal models have explored the influence of light on eye growth and potential treatments for myopia. In children, the concept of premyopia and early myopia control implementation is gaining attention. Various clinical trials have demonstrated the efficacy and safety of different treatments, such as spectacle lens designs, contact lenses, and pharmaceutical options. The ethics of including control arms in clinical trials and the IMI recommendations for trial protocols are also discussed.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Meeting Abstract
Ophthalmology
Rebecca Weng, Huy Dinh Minh Tran, Daniel P. Spiegel, Bjorn Drobe, Thomas John Naduvilath, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Padmaja Sankaridurg, Huy Dinh Minh Tran, Thomas John Naduvilath, Thao Ha, Tuan Diep Tran, Krupa Philip, Rebecca Weng, Minas Coroneo, Yen Hai Tran
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Dean Psarakis, Craig Woods, Thomas John Naduvilath, Nina Tahhan, Senuri Karunaratne, Divya Jagadeesh, Arthur Back, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Xiao Nicole Liu, Thomas John Naduvilath, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Huy Dinh Minh Tran, Yen Hai Tran, Thao Ha, Tuan Diep Tran, Thomas John Naduvilath, Krupa Philip, Rebecca Weng, Monica Jong, Minas Coroneo, Padmaja Sankaridurg
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Article
Neurosciences
Ryan P. Silk, Hanagh R. Winter, Ouria Dkhissi-Benyahya, Carmella Evans -Molina, Alan W. Stitt, Vijay K. Tiwari, David A. Simpson, Eleni Beli
Summary: This study investigates whether diabetes affects the daily rhythm of gene expression in the retina. The results show that diabetic mice exhibited phase advancement in the expression of certain genes compared to non-diabetic mice. The study also identified oxygen-sensing mechanisms and HIF1alpha as potential upstream regulators. These findings provide important insights into the development of diabetic retinopathy.
Article
Neurosciences
Krishnamachari S. Prahalad, Daniel R. Coates
Summary: Visual stimuli presented around the time of a saccade can be perceived differently by the visual system, including a reduction in the harmful impact of flankers. This study investigated the effects of microsaccades on crowded stimuli placed 20 arc minutes from the center of gaze. The findings suggest two separate pre-saccadic benefits, one that regularizes the crowding zone and another that specifically benefits microsaccade targets surrounded by tangential flankers.
Article
Neurosciences
Chandrika Ravisankar, Christopher W. Tyler, Clifton M. Schor, Shrikant R. Bharadwaj
Summary: This study revealed that less than one-third of adults with normal binocular vision were able to successfully free-fuse random-dot image pairs and identify the embedded stereoscopic shapes. The successful participants showed a dissociation of vergence and accommodative responses, while the unsuccessful ones either exhibited strong vergence and accommodation or weak vergence and strong accommodation. Task performance of the unsuccessful cluster improved significantly with pharmacological paralysis of accommodation. A minority of participants also learned to dissociate one direction of their vergence and accommodation crosslinks with repeated free-fusion trials, optimizing their task performance.